Miconazole Vaginal

37 interactions 192 cited references
Also sold as: Lagicam Monistat Monistat® 1 Combination Pack Dual-Pak® Monistat® 3 Combination Pack® Monistat® 3 Suppositories Monistat® 7 Combination Pack® Monistat® 7 Cream Monistat® 7 Suppositories Vagistat
About Miconazole Vaginal

Vaginal miconazole is used to treat vaginal yeast infections in adults and children 12 years of age and older. Miconazole is in a class of antifungal medications called imidazoles. It works by stopping the growth of fungi that cause infection. Read the full Miconazole Vaginal drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Miconazole Vaginal Amiodarone Nexterone Increased amiodarone exposure Details Miconazole Vaginal Carvedilol Coreg Increased carvedilol concentrations and an increased risk of bradycardia or heart block Details Miconazole Vaginal Celecoxib Celebrex Increased celecoxib exposure Details Miconazole Vaginal Cilostazol Pletal® Increased cilostazol exposure Details Miconazole Vaginal Domperidone Increased domperidone exposure and an increased risk of QT interval prolongation Details Miconazole Vaginal Erdafitinib Balversa Increased erdafitinib exposure Details Miconazole Vaginal Escitalopram Lexapro Increased risk of serotonin syndrome (hypertension, tachycardia, hyperthermia, myoclonus, mental status changes) Details Miconazole Vaginal Etonogestrel Nexplanon Increased etonogestrel exposure Details Miconazole Vaginal Fosphenytoin Cerebyx Increased phenytoin or fosphenytoin (prodrug of phenytoin) exposure and an increased risk of phenytoin or fosphenytoin toxicity (a... Details Miconazole Vaginal Glimepiride Amaryl Severe hypoglycemia Details Miconazole Vaginal Ifosfamide Ifex Decreased ifosfamide effectiveness Details Miconazole Vaginal Meloxicam Alloxate Increased meloxicam exposure and reduced meloxicam metabolic clearance Details Miconazole Vaginal Methadone Diskets Increased methadone exposure and an increased risk of opioid adverse effects Details Miconazole Vaginal Naloxegol Movantik Increased naloxegol exposure Details Miconazole Vaginal Olaparib Lynparza Increased olaparib exposure Details Miconazole Vaginal Phenobarbital Fidoquel Increased PHENobarbital exposure and an increased risk of PHENobarbital-related adverse effects Details Miconazole Vaginal Phenytoin Dilantin Increased phenytoin or fosphenytoin (prodrug of phenytoin) exposure and an increased risk of phenytoin or fosphenytoin toxicity (a... Details Miconazole Vaginal Piperaquine Increased exposure of piperaquine Details Miconazole Vaginal Primidone Mysoline Increased PHENobarbital exposure and an increased risk of PHENobarbital-related adverse effects Details Miconazole Vaginal Simeprevir Olysio® Increased simeprevir exposure Details Miconazole Vaginal Voriconazole Vfend Increased voriconazole exposure Details Miconazole Vaginal Warfarin Coumadin Increased warfarin exposure, an increased INR and an increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.