Mifepristone
225 interactions 13 explained in plain English
Also sold as:
Korlym
Mifeprex
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Hydrocortisone
Neratinib
Ciclesonide Oral Inhalation
Diflorasone Topical
Clindamycin Topical
Desonide
Contraindicated
Mifepristone Everolimus Afinitor Increased everolimus exposure and an increased miFEPRIStone exposure Details Mifepristone Fentanyl Transdermal Patch Duragesic® Increased fentaNYL exposure and risk of adverse events Details Mifepristone Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Mifepristone Fludrocortisone Acetate Florinef® An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Flunisolide Nasal Spray Nasalide® An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Flunisolide Oral Inhalation AeroBid® Inhaler System An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Fluocinolone Capex An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Fluocinolone Topical Capex® Shampoo An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Fluocinonide Vanos An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Fluocinonide Topical Dermacin® An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Flurandrenolide Topical Cordran An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Halcinonide Topical Halog An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Halobetasol Topical Duobrii (as a combination product containing Halobetasol, Tazarotene) An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Hydrocortisone Ala-Cort Increased CYP3A4 substrate exposure and an increased risk of autoimmune disorders and acute adrenal insufficiency, that may lead t... Details Mifepristone Hydrocortisone Injection A-Hydrocort® Increased CYP3A4 substrate exposure and an increased risk of autoimmune disorders and acute adrenal insufficiency, that may lead t... Details Mifepristone Ivabradine Corlanor Increased ivabradine exposure, an increased risk of ivabradine-related adverse effects and an increased risk of QT prolongation Details Mifepristone Ketoconazole Topical Extina® Foam Increased miFEPRIStone exposure, increased ketoconazole exposure, an increased risk of ketoconazole-related adverse reactions and... Details Mifepristone Loteprednol Etabonate Alrex An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Loteprednol Ophthalmic Alrex An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Lovastatin Altocor® Increased lovastatin exposure and an increased risk of lovastatin-related adverse effects, such as, myopathy and rhabdomyolysis Details Mifepristone Lurasidone Latuda Increased lurasidone exposure Details Mifepristone Midostaurin Rydapt Increased CYP3A4 substrate with NTI exposure Details Mifepristone Mometasone Asmanex An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Mometasone Nasal Spray Nasonex An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Mometasone Oral Inhalation Asmanex An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Mometasone Topical Elocon® An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Naloxegol Movantik Increased naloxegol exposure and an increased risk of naloxegol-related adverse effects Details Mifepristone Neratinib Nerlynx Increased CYP3A4 substrate with NTI exposure Details Mifepristone Olaparib Lynparza Increased olaparib exposure and an increased miFEPRIStone exposure DetailsMajor
Mifepristone Acetaminophen And Codeine Capital® & Codeine Explained Increased codeine and morphine exposure Details Mifepristone Omeprazole Gastrobim Explained Increased CYP3A4 substrate exposure Details Mifepristone Amitriptyline Elavil Explained An increased risk of QT interval prolongation Details Mifepristone Sertraline Explained Increased sertraline exposure and an increased risk of QT interval prolongation Details Mifepristone Buprenorphine Belbuca Explained An increased risk of QT interval prolongation, increased buprenorphine exposure and an increased risk of buprenorphine-related adv... Details Mifepristone Relugolix Orgovyx Explained Increased relugolix exposure and an increased risk of QT interval prolongation Details Mifepristone Alpelisib Piqray Increased CYP3A4 substrate exposure Details Mifepristone Amisulpride Injection Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Mifepristone Apixaban Eliquis Explained Increased apixaban exposure and an increased risk of bleeding Details Mifepristone Arsenic Trioxide Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Mifepristone Aripiprazole Injection Abilify Increased ARIPiprazole exposure and an increased risk of QT interval prolongation DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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