Mifepristone

225 interactions 13 explained in plain English
Also sold as: Korlym Mifeprex
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Contraindicated

Mifepristone Everolimus Afinitor Increased everolimus exposure and an increased miFEPRIStone exposure Details Mifepristone Fentanyl Transdermal Patch Duragesic® Increased fentaNYL exposure and risk of adverse events Details Mifepristone Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Mifepristone Fludrocortisone Acetate Florinef® An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Flunisolide Nasal Spray Nasalide® An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Flunisolide Oral Inhalation AeroBid® Inhaler System An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Fluocinolone Capex An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Fluocinolone Topical Capex® Shampoo An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Fluocinonide Vanos An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Fluocinonide Topical Dermacin® An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Flurandrenolide Topical Cordran An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Halcinonide Topical Halog An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Halobetasol Topical Duobrii (as a combination product containing Halobetasol, Tazarotene) An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Hydrocortisone Ala-Cort Increased CYP3A4 substrate exposure and an increased risk of autoimmune disorders and acute adrenal insufficiency, that may lead t... Details Mifepristone Hydrocortisone Injection A-Hydrocort® Increased CYP3A4 substrate exposure and an increased risk of autoimmune disorders and acute adrenal insufficiency, that may lead t... Details Mifepristone Ivabradine Corlanor Increased ivabradine exposure, an increased risk of ivabradine-related adverse effects and an increased risk of QT prolongation Details Mifepristone Ketoconazole Topical Extina® Foam Increased miFEPRIStone exposure, increased ketoconazole exposure, an increased risk of ketoconazole-related adverse reactions and... Details Mifepristone Loteprednol Etabonate Alrex An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Loteprednol Ophthalmic Alrex An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Lovastatin Altocor® Increased lovastatin exposure and an increased risk of lovastatin-related adverse effects, such as, myopathy and rhabdomyolysis Details Mifepristone Lurasidone Latuda Increased lurasidone exposure Details Mifepristone Midostaurin Rydapt Increased CYP3A4 substrate with NTI exposure Details Mifepristone Mometasone Asmanex An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Mometasone Nasal Spray Nasonex An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Mometasone Oral Inhalation Asmanex An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Mometasone Topical Elocon® An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details Mifepristone Naloxegol Movantik Increased naloxegol exposure and an increased risk of naloxegol-related adverse effects Details Mifepristone Neratinib Nerlynx Increased CYP3A4 substrate with NTI exposure Details Mifepristone Olaparib Lynparza Increased olaparib exposure and an increased miFEPRIStone exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.