Mitapivat
295 interactions 80 cited referencesMitapivat is used to treat hemolytic anemia (a blood disorder that occurs when red blood cells are destroyed faster than they can be made in the body) in people with pyruvate kinase deficiency. Mitapivat is in a class of medications called pyruvate kinase activators. It works by increasing pyruvate kinase available to… Read the full Mitapivat drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Mitapivat Fentanyl Transdermal Patch Duragesic® Reduced CYP3A substrate exposure Details Mitapivat Finerenone Kerendia Reduced finerenone exposure and reduced efficacy of finerenone Details Mitapivat Ibrexafungerp Brexafemme Reduced CYP3A substrate exposure Details Mitapivat Ibrutinib Imbruvica Reduced CYP3A substrate exposure Details Mitapivat Infigratinib Truseltiq Reduced CYP3A substrate exposure Details Mitapivat Ivabradine Corlanor Reduced CYP3A substrate exposure Details Mitapivat Ketoconazole Topical Extina® Foam Increased mitapivat exposure and an increased risk of mitapivat-related adverse reactions Details Mitapivat Lefamulin Xenleta Increased mitapivat exposure Details Mitapivat Lenacapavir Injection Sunlenca Reduced lenacapavir exposure which may result in the loss of therapeutic effect and development of resistance to lenacapavir, incr... Details Mitapivat Lenacapavir Oral Sunlenca Reduced lenacapavir exposure which may result in the loss of therapeutic effect and development of resistance to lenacapavir, incr... Details Mitapivat Leniolisib Joenja Reduced leniolisib exposure and reduced efficacy of leniolisib Details Mitapivat Letermovir Injection Prevymis Increased mitapivat exposure Details Mitapivat Levonorgestrel After banger Reduced hormonal contraceptive exposure Details Mitapivat Levonorgestrel Intrauterine System Kyleena Reduced hormonal contraceptive exposure Details Mitapivat Lovastatin Altocor® Reduced CYP3A substrate exposure Details Mitapivat Lumateperone Caplyta Reduced lumateperone exposure Details Mitapivat Lurasidone Latuda Reduced CYP3A substrate exposure Details Mitapivat Maraviroc Selzentry Reduced CYP3A substrate exposure Details Mitapivat Medroxyprogesterone Amen® Reduced hormonal contraceptive exposure Details Mitapivat Medroxyprogesterone Injection Depo-Provera Reduced hormonal contraceptive exposure Details Mitapivat Midazolam Nasal Spray Nayzilam Reduced CYP3A substrate exposure Details Mitapivat Midazolam Injection Nayzilam Reduced CYP3A substrate exposure Details Mitapivat Midostaurin Rydapt Reduced CYP3A substrate exposure Details Mitapivat Adagrasib Krazati Increased mitapivat exposure and an increased risk of mitapivat-related adverse reactions Details Mitapivat Alfentanil Reduced CYP3A substrate exposure Details Mitapivat Amprenavir Increased mitapivat exposure Details Mitapivat Apalutamide Erleada Reduced mitapivat exposure and reduced efficacy of mitapivat Details Mitapivat Aprepitant Aponvie Increased mitapivat exposure Details Mitapivat Artemether Reduced artemether/lumefantrine exposure, reduced efficacy of artemether/lumefantrine, loss of antimalarial efficacy, reduced CYP3... Details Mitapivat Astemizole Reduced CYP3A substrate exposure Details Mitapivat Atazanavir Reyataz Increased mitapivat exposure and reduced CYP3A4 substrate exposure Details Mitapivat Atrasentan Reduced atrasentan exposure and reduced efficacy of atrasentan Details Mitapivat Berotralstat Orladeyo Increased mitapivat exposure Details Mitapivat Boceprevir Increased mitapivat exposure and an increased risk of mitapivat-related adverse reactions Details Mitapivat Bosentan Reduced mitapivat exposure and reduced efficacy of mitapivat Details Mitapivat Buspirone Bucapsol Reduced CYP3A substrate exposure Details Mitapivat Carbamazepine Carbatrol Reduced mitapivat exposure and reduced efficacy of mitapivat Details Mitapivat Cenobamate Xcopri Reduced mitapivat exposure and reduced efficacy of mitapivat Details Mitapivat Ceritinib Zykadia Increased mitapivat exposure, an increased risk of mitapivat-related adverse reactions and reduced CYP3A substrate exposure Details Mitapivat Ciprofloxacin Increased mitapivat exposure DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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