Mitapivat
295 interactions 80 cited referencesMitapivat is used to treat hemolytic anemia (a blood disorder that occurs when red blood cells are destroyed faster than they can be made in the body) in people with pyruvate kinase deficiency. Mitapivat is in a class of medications called pyruvate kinase activators. It works by increasing pyruvate kinase available to… Read the full Mitapivat drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Mitapivat Cisapride Propulsid® Reduced CYP3A substrate exposure Details Mitapivat Clarithromycin Biaxin Increased mitapivat exposure and an increased risk of mitapivat-related adverse reactions Details Mitapivat Clofazimine Increased mitapivat exposure Details Mitapivat Cobicistat Tybost Increased mitapivat exposure and an increased risk of mitapivat-related adverse reactions Details Mitapivat Conivaptan Vaprisol Increased mitapivat exposure and reduced CYP3A4 substrate exposure Details Mitapivat Crinecerfont Reduced crinecerfont exposure and reduced efficacy of crinecerfont Details Mitapivat Crizotinib Xalkori Increased mitapivat exposure and reduced CYP3A4 substrate exposure Details Mitapivat Cyclosporine Atopica Increased P-gp substrate exposure; reduced CYP3A substrate exposure Details Mitapivat Dabrafenib Tafinlar Altered (increased/reduced) mitapivat exposure Details Mitapivat Daridorexant Reduced CYP3A substrate exposure Details Mitapivat Darifenacin Enablex Reduced CYP3A substrate exposure Details Mitapivat Darunavir Increased mitapivat exposure and reduced CYP3A4 substrate exposure Details Mitapivat Defactinib Reduced defactinib exposure and reduced efficacy of defactinib Details Mitapivat Desogestrel Reduced hormonal contraceptive exposure Details Mitapivat Deutivacaftor Reduced deutivacaftor exposure and reduced efficacy of deutivacaftor Details Mitapivat Dienogest Reduced hormonal contraceptive exposure Details Mitapivat Dihydroergotamine Brekiya Reduced CYP3A substrate exposure Details Mitapivat Diltiazem Cardizem Increased mitapivat exposure Details Mitapivat Dipyrone Reduced mitapivat exposure and reduced efficacy of mitapivat Details Mitapivat Dordaviprone Reduced dordaviprone exposure and reduced efficacy of dordaviprone Details Mitapivat Dronedarone Multaq Increased mitapivat exposure and reduced CYP3A4 substrate exposure Details Mitapivat Drospirenone Reduced hormonal contraceptive exposure Details Mitapivat Duvelisib Copiktra Increased mitapivat exposure Details Mitapivat Efavirenz Reduced mitapivat exposure and reduced efficacy of mitapivat Details Mitapivat Elagolix Orilissa Reduced mitapivat exposure and reduced efficacy of mitapivat Details Mitapivat Eletriptan Relpax Reduced CYP3A substrate exposure Details Mitapivat Elinzanetant Lynkuet Reduced elinzanetant exposure and reduced efficacy of elinzanetant Details Mitapivat Elvitegravir Reduced CYP3A substrate exposure Details Mitapivat Ensartinib Reduced ensartinib exposure Details Mitapivat Enzalutamide Xtandi Reduced mitapivat exposure and reduced efficacy of mitapivat Details Mitapivat Eplerenone Inspra Reduced CYP3A substrate exposure Details Mitapivat Ergotamine Ergomar Reduced CYP3A substrate exposure Details Mitapivat Erythromycin Erythrocin Stearate Increased mitapivat exposure Details Mitapivat Estetrol Reduced hormonal contraceptive exposure Details Mitapivat Ethinyl Estradiol Reduced hormonal contraceptive exposure Details Mitapivat Ethynodiol Reduced hormonal contraceptive exposure Details Mitapivat Etonogestrel Nexplanon Reduced hormonal contraceptive exposure Details Mitapivat Etravirine Intelence Reduced mitapivat exposure and reduced efficacy of mitapivat Details Mitapivat Fedratinib Inrebic Increased mitapivat exposure Details Mitapivat Fentanyl Reduced CYP3A substrate exposure DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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