Mometasone Nasal Spray

41 interactions 260 cited references
Also sold as: Nasonex Nasonex®
About Mometasone Nasal Spray

Mometasone nasal spray is used to prevent and relieve symptoms of sneezing, runny, stuffy, or itchy nose caused by hay fever or other allergies. It is also used to treat nasal polyps (swelling of the lining of the nose). Mometasone nasal spray should not be used to treat symptoms (e.g., sneezing, stuffy, runny, itchy n… Read the full Mometasone Nasal Spray drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mifepristone Desmopressin Aspirin Atazanavir Bemiparin Carbamazepine
2 Contraindicated 23 Major 16 Moderate
All (41) Contraindicated (2) Major (23) Moderate (16)

Moderate

Mometasone Nasal Spray Auranofin Ridaura Increased risk of auranofin-related adverse effects Details Mometasone Nasal Spray Clarithromycin Biaxin Increased mometasone plasma concentrations Details Mometasone Nasal Spray Gallium Ga 68 Dotatate Increased risk of false negative imaging Details Mometasone Nasal Spray Indapamide An increased risk of hypokalemia Details Mometasone Nasal Spray Indinavir Increased mometasone plasma concentrations Details Mometasone Nasal Spray Insulin Afrezza Reduced blood glucose lowering effect of insulin Details Mometasone Nasal Spray Insulin Lispro, Recombinant Admelog May decrease blood glucose lowering effect of insulin lispro Details Mometasone Nasal Spray Ketoconazole Extina Increased mometasone plasma concentrations Details Mometasone Nasal Spray Metformin Fortamet® An increased risk of hyperglycemia and potential loss of glycemic control Details Mometasone Nasal Spray Nefazodone Increased mometasone plasma concentrations Details Mometasone Nasal Spray Nelfinavir Viracept Increased mometasone plasma concentrations Details Mometasone Nasal Spray Olodaterol Striverdi An increased risk of hypokalemia Details Mometasone Nasal Spray Rotavirus Vaccine, Live An inadequate immunological response to the vaccine Details Mometasone Nasal Spray Saquinavir Increased mometasone plasma concentrations Details Mometasone Nasal Spray Telithromycin Increased mometasone plasma concentrations Details Mometasone Nasal Spray Testosterone Androderm Increased risk of edema Details

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