Nebivolol

220 interactions 1 explained in plain English 373 cited references
Also sold as: Bystolic Bystolic®
About Nebivolol

Nebivolol is a beta blocker used to treat high blood pressure, either alone or combined with other medications. Read the full Nebivolol drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mavorixafor Cinacalcet Clonidine Olodaterol Oral Inhalation Indacaterol Oral Inhalation Bupropion
1 Contraindicated 59 Major 160 Moderate
All (220) Contraindicated (1) Major (59) Moderate (160)

Moderate

Nebivolol Liraglutide Injection Saxenda Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Nebivolol Lixisenatide Injection Adlyxin® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Nebivolol Meclofenamate Meclodium® Reduced antihypertensive effect Details Nebivolol Mefenamic Acid Ponstel® Reduced antihypertensive effect Details Nebivolol Meloxicam Alloxate Reduced antihypertensive effect Details Nebivolol Meloxicam Injection Alloxate Reduced antihypertensive effect Details Nebivolol Metformin Fortamet® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Nebivolol Methimazole Felanorm Altered metabolism of the beta-adrenergic blocker Details Nebivolol Methyldopa Aldomet® Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Nebivolol Miglitol Glyset® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Nebivolol Nabumetone Relafen Reduced antihypertensive effect Details Nebivolol Naproxen Aleve Reduced antihypertensive effect Details Nebivolol Nateglinide Starlix® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Nebivolol Aceclofenac Reduced antihypertensive effect Details Nebivolol Acemetacin Reduced antihypertensive effect Details Nebivolol Acetyldigoxin Increased risk of bradycardia and possible digitalis glycoside toxicity Details Nebivolol Albiglutide Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Nebivolol Amtolmetin Guacil Reduced antihypertensive effect Details Nebivolol Asenapine Saphris An increased risk of hypotension Details Nebivolol Atazanavir Reyataz An increased risk of PR interval prolongation Details Nebivolol Bromfenac Bromsite Reduced antihypertensive effect Details Nebivolol Bufexamac Reduced antihypertensive effect Details Nebivolol Bunazosin An exaggerated hypotensive response to the first dose of the alpha blocker Details Nebivolol Carbimazole Altered metabolism of the beta-adrenergic blocker Details Nebivolol Celecoxib Celebrex Reduced antihypertensive effect Details Nebivolol Chlorpropamide Diabinese® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Nebivolol Choline Salicylate Reduced antihypertensive effect Details Nebivolol Cimetidine Tagamet Increased nebivolol plasma levels Details Nebivolol Clonixin Reduced antihypertensive effect Details Nebivolol Deslanoside Increased risk of bradycardia and possible digitalis glycoside toxicity Details Nebivolol Dexibuprofen Reduced antihypertensive effect Details Nebivolol Dexketoprofen Reduced antihypertensive effect Details Nebivolol Diclofenac Aleve Arthritis Pain Reduced antihypertensive effect Details Nebivolol Diflunisal Dolobid Reduced antihypertensive effect Details Nebivolol Digitoxin Increased risk of bradycardia and possible digitalis glycoside toxicity Details Nebivolol Dipyrone Reduced antihypertensive effect Details Nebivolol Droxicam Reduced antihypertensive effect Details Nebivolol Dulaglutide Trulicity Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Nebivolol Etofenamate Reduced antihypertensive effect Details Nebivolol Etoricoxib Reduced antihypertensive effect Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.