Ofloxacin Ophthalmic

Name: Ofloxacin Ophthalmic Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

337 interactions 674 cited references

Also sold as: Ocuflox Ocuflox®

About Ofloxacin Ophthalmic

Ophthalmic ofloxacin ophthalmic is used to treat bacterial infections of the eye, including conjunctivitis (pink eye) and ulcers of the cornea. Ofloxacin is in a class of medications called quinolone antibiotics. It works by killing bacterial cells that cause infection. Read the full Ofloxacin Ophthalmic drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Mesoridazine Pimozide Piperaquine Saquinavir Bepridil

12 Contraindicated 240 Major 84 Moderate 1 Minor

All (337) Contraindicated (12) Major (240) Moderate (84) Minor (1)

Moderate

Ofloxacin Ophthalmic Tolmetin Tolectin 600 An increased risk of seizures Details Ofloxacin Ophthalmic Typhoid Vaccine, Live Vivotif A decreased immunological response to the typhoid vaccine Details Ofloxacin Ophthalmic Valdecoxib An increased risk of seizures Details Ofloxacin Ophthalmic Zinc Decreased efficacy of ofloxacin Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.