Oxacillin
18 interactions
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 11, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Demeclocycline
Doxycycline Injection
Eravacycline Injection
Estradiol
Estradiol Topical
Estradiol Transdermal Patch
Major
Oxacillin Demeclocycline Declomycin® Decreased antibacterial effectiveness Details Oxacillin Doxycycline Injection Acticlate Decreased antibacterial effectiveness Details Oxacillin Eravacycline Injection Xerava Decreased antibacterial effectiveness Details Oxacillin Estradiol Delestrogen Decreased contraceptive effectiveness Details Oxacillin Estradiol Topical Divigel Decreased contraceptive effectiveness Details Oxacillin Estradiol Transdermal Patch Alora® Decreased contraceptive effectiveness Details Oxacillin Hydroxychloroquine Plaquenil An increased risk of seizures Details Oxacillin Levonorgestrel After banger Decreased contraceptive effectiveness Details Oxacillin Levonorgestrel Intrauterine System Kyleena Decreased contraceptive effectiveness Details Oxacillin Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Oxacillin Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Oxacillin Minocycline Amzeeq Decreased antibacterial effectiveness Details Oxacillin Minocycline Topical Amzeeq Decreased antibacterial effectiveness DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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