Oxprenolol

Name: Oxprenolol Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

59 interactions 2 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Albuterol Oral Inhalation Clonidine Transdermal Patch Indacaterol Oral Inhalation Lacosamide Injection Methylergonovine Olodaterol Oral Inhalation

6 Major 53 Moderate

All (59) Major (6) Moderate (53)

Moderate

Oxprenolol Lixisenatide Injection Adlyxin® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Oxprenolol Meclofenamate Meclodium® Reduced antihypertensive effect Details Oxprenolol Mefenamic Acid Ponstel® Reduced antihypertensive effect Details Oxprenolol Meloxicam Alloxate Reduced antihypertensive effect Details Oxprenolol Meloxicam Injection Alloxate Reduced antihypertensive effect Details Oxprenolol Metformin Fortamet® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Oxprenolol Methimazole Felanorm Altered metabolism of the beta-adrenergic blocker Details Oxprenolol Methyldopa Aldomet® Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Oxprenolol Miglitol Glyset® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Oxprenolol Nabumetone Relafen Reduced antihypertensive effect Details Oxprenolol Naproxen Aleve Reduced antihypertensive effect Details Oxprenolol Nateglinide Starlix® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Oxprenolol Nifedipine Adalat® An increased risk of congestive heart failure, severe hypotension or exacerbation of angina Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.