Penicillin G Procaine Injection

39 interactions 152 cited references
Also sold as: Bactracillin G Bicillin Duracillin A-S ® Norocillin Pfizerpen A-S®
About Penicillin G Procaine Injection

Penicillin G procaine injection is used to treat certain infections caused by bacteria. Penicillin G procaine injection should not be used to treat gonorrhea (a sexually transmitted disease) or early in the treatment of certain serious infections. Penicillin G procaine injection is in a class of medications called peni… Read the full Penicillin G Procaine Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Chlortetracycline Cholera Vaccine, Live Demeclocycline Desogestrel Dienogest Doxycycline
27 Major 1 Moderate 11 Minor
All (39) Major (27) Moderate (1) Minor (11)

Major

Penicillin G Procaine Injection Chlortetracycline Decreased antibacterial effectiveness Details Penicillin G Procaine Injection Cholera Vaccine, Live Reduced immune response to the cholera vaccine Details Penicillin G Procaine Injection Demeclocycline Declomycin® Decreased antibacterial effectiveness Details Penicillin G Procaine Injection Desogestrel Decreased contraceptive effectiveness Details Penicillin G Procaine Injection Dienogest Decreased contraceptive effectiveness Details Penicillin G Procaine Injection Doxycycline Acticlate Decreased antibacterial effectiveness Details Penicillin G Procaine Injection Drospirenone Decreased contraceptive effectiveness Details Penicillin G Procaine Injection Eravacycline Xerava Decreased antibacterial effectiveness Details Penicillin G Procaine Injection Estradiol Delestrogen Decreased contraceptive effectiveness Details Penicillin G Procaine Injection Ethinyl Estradiol Decreased contraceptive effectiveness Details Penicillin G Procaine Injection Ethynodiol Decreased contraceptive effectiveness Details Penicillin G Procaine Injection Gestodene Decreased contraceptive effectiveness Details Penicillin G Procaine Injection Levonorgestrel After banger Decreased contraceptive effectiveness Details Penicillin G Procaine Injection Lymecycline Decreased antibacterial effectiveness Details Penicillin G Procaine Injection Meclocycline Decreased antibacterial effectiveness Details Penicillin G Procaine Injection Mestranol Decreased contraceptive effectiveness Details Penicillin G Procaine Injection Methacycline Decreased antibacterial effectiveness Details Penicillin G Procaine Injection Minocycline Amzeeq Decreased antibacterial effectiveness Details Penicillin G Procaine Injection Nomegestrol Decreased contraceptive effectiveness Details Penicillin G Procaine Injection Norethindrone Aygestin Decreased contraceptive effectiveness Details Penicillin G Procaine Injection Norgestimate Decreased contraceptive effectiveness Details Penicillin G Procaine Injection Norgestrel Decreased contraceptive effectiveness Details Penicillin G Procaine Injection Oxytetracycline Decreased antibacterial effectiveness Details Penicillin G Procaine Injection Rolitetracycline Decreased antibacterial effectiveness Details Penicillin G Procaine Injection Sarecycline Seysara Decreased antibacterial effectiveness Details Penicillin G Procaine Injection Tetracycline Achromycin V® Decreased antibacterial effectiveness Details Penicillin G Procaine Injection Tigecycline Tygacil Decreased antibacterial effectiveness Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.