Phenytoin

Major

Phenytoin Omeprazole Gastrobim Explained Increased phenytoin exposure or fosphenytoin (prodrug of phenytoin), an increased risk of phenytoin or fosphenytoin toxicity (atax... Details Phenytoin Amitriptyline Elavil Explained An increased risk of phenytoin exposure and reduced TCA exposure Details Phenytoin Sertraline Explained Increased risk of phenytoin toxicity and reduced efficacy of sertraline Details Phenytoin Buprenorphine Belbuca Explained Reduced buprenorphine exposure and reduced efficacy of buprenorphine Details Phenytoin Relugolix Orgovyx Explained Reduced relugolix exposure and reduced efficacy of relugolix Details Phenytoin Simvastatin Flolipid Explained Reduced simvastatin exposure Details Phenytoin Abemaciclib Verzenio Explained Decreased abemaciclib plasma concentration Details Phenytoin Acalabrutinib Calquence Reduced acalabrutinib exposure Details Phenytoin Albendazole Albendamax Reduced albendazole active metabolite exposure Details Phenytoin Alpelisib Piqray Reduced alpelisib exposure and reduced efficacy of alpelisib Details Phenytoin Apixaban Eliquis Explained Reduced apixaban exposure, reduced efficacy of apixaban and an increased risk of stroke and other thromboembolic events Details Phenytoin Apremilast Otezla Reduced apremilast exposure and an reduced efficacy of apremilast Details Phenytoin Aripiprazole Injection Abilify Reduced ARIPiprazole exposure Details Phenytoin Asciminib Scemblix Reduced asciminib exposure, reduced efficacy of asciminib, an increased phenytoin or fosphenytoin (prodrug of phenytoin) exposure... Details Phenytoin Aspirin Acuprin® Altered phenytoin or fosphenytoin (prodrug of phenytoin) exposure and an increased risk of phenytoin or fosphenytoin toxicity Details Phenytoin Aspirin Rectal Aspirin Altered phenytoin or fosphenytoin (prodrug of phenytoin) exposure and an increased risk of phenytoin or fosphenytoin toxicity Details Phenytoin Atogepant Qulipta Reduced atogepant exposure Details Phenytoin Avapritinib Ayvakit Reduced avapritinib exposure and reduced efficacy of avapritinib Details Phenytoin Azathioprine Azasan An increased risk of hepatotoxicity Details Phenytoin Belumosudil Rezurock Explained Reduced belumosudil exposure and reduced efficacy of belumosudil Details Phenytoin Betrixaban Bevyxxa® Decreased betrixaban exposure Details Phenytoin Atorvastatin Atorvaliq Reduced atorvastatin exposure and reduced efficacy of atorvastatin Details Phenytoin Cariprazine Vraylar Explained Effects on the cariprazine exposure has not been evaluated and the net effect is unclear Details Phenytoin Abiraterone Abirtega Reduced abiraterone exposure and reduced efficacy of abiraterone Details Phenytoin Afatinib Gilotrif Decreased afatinib exposure Details Phenytoin Aficamten Reduced aficamten exposure and reduced efficacy of aficamten Details Phenytoin Amlodipine Amvaz® Reduced amLODIPine exposure Details Phenytoin Axitinib Inlyta Reduced axitinib exposure Details Phenytoin Beclomethasone Nasal Spray Beconase Reduced corticosteroid exposure Details Phenytoin Beclomethasone Oral Inhalation Beclovent® Reduced corticosteroid exposure Details Phenytoin Bedaquiline Sirturo Reduced bedaquiline exposure and reduced efficacy of bedaquiline Details Phenytoin Bendamustine Injection Belrapzo Reduced bendamustine exposure and reduced efficacy of bendamustine Details Phenytoin Bleomycin Blenoxane® Reduced phenytoin or fosphenytoin (prodrug of phenytoin) exposure Details Phenytoin Bortezomib Boruzu Reduced bortezomib exposure Details Phenytoin Bosutinib Bosulif Reduced bosutinib exposure and reduced efficacy of bosutinib Details Phenytoin Brexpiprazole Rexulti Reduced brexpiprazole exposure Details Phenytoin Brigatinib Alunbrig Reduced brigatinib efficacy Details Phenytoin Budesonide Entocort Reduced corticosteroid exposure Details Phenytoin Budesonide Nasal Spray Rhinocort Reduced corticosteroid exposure Details Phenytoin Budesonide Oral Inhalation Pulmicort Reduced corticosteroid exposure Details