Praziquantel

Name: Praziquantel Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

6 interactions

Also sold as: Biltricide Biltricide® Droncit Giarcidia

About Praziquantel

Praziquantel is used to treat schistosoma (infection with a type of worm that lives in the bloodstream) and liver fluke (infection with a type of worm that lives in or near the liver). Praziquantel is in a class of medications called anthelmintics. It works by killing the worms. Read the full Praziquantel drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Dexamethasone Injection Dexamethasone Ophthalmic Ketoconazole Topical Letermovir Injection Nafcillin Injection

2 Contraindicated 3 Major 1 Moderate

All (6) Contraindicated (2) Major (3) Moderate (1)

Major

Praziquantel Ketoconazole Topical Extina® Foam Increased praziquantel exposure Details Praziquantel Letermovir Injection Prevymis Increased CYP3A substrate exposure Details Praziquantel Nafcillin Injection Unipen® Injection Reduced praziquantel exposure and reduced efficacy of praziquantel Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.