Quinidine

91 interactions 8 explained in plain English
Also sold as: Cardioquin® Cin-Quin® Duraquin® Quinact® Quinaglute® Quinalan® Quinatime® Quinidex® Quinora®
About Quinidine

Quinidine is an antiarrhythmic medication used to treat certain types of irregular heartbeats. Read the full Quinidine drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Lefamulin Ketoconazole Topical Colchicine Oxaliplatin Injection Dofetilide Goserelin Implant
3 Contraindicated 80 Major 8 Moderate
All (91) Contraindicated (3) Major (80) Moderate (8)

Major

Quinidine Gatifloxacin Ophthalmic Zymar® An increased risk of QT interval prolongation Details Quinidine Gemifloxacin Factive An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Quinidine Glasdegib Daurismo Increased risk of QT interval prolongation Details Quinidine Goserelin Implant Zoladex Increased risk of QT interval prolongation Details Quinidine Granisetron Transdermal Patch Sancuso An increased risk of QT interval prolongation Details Quinidine Granisetron Injection Granisol An increased risk of QT interval prolongation Details Quinidine Histrelin Implant Supprelin Increased risk of QT interval prolongation Details Quinidine Hydroxychloroquine Plaquenil Increased risk of QT interval prolongation Details Quinidine Inotuzumab Ozogamicin Injection Besponsa Increased risk of QT interval prolongation Details Quinidine Isradipine DynaCirc® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Quinidine Ivabradine Corlanor Increased risk of QT prolongation Details Quinidine Lacosamide Injection Motpoly An increased risk of AV block, bradycardia, and ventricular tachyarrhythmia Details Quinidine Lanreotide Injection Somatuline Altered exposure to CYP3A4 substrate Details Quinidine Lenvatinib Lenvima Increased risk of QT-interval prolongation Details Quinidine Letermovir Injection Prevymis Increased CYP3A substrate exposure Details Quinidine Levofloxacin Levaquin Increased risk of QT interval prolongation Details Quinidine Levofloxacin Injection Levaquin Increased risk of QT interval prolongation Details Quinidine Loperamide Diamode Increased loperamide exposure, an increased risk of loperamide-related adverse reactions, an increased risk of QT interval prolong... Details Quinidine Mefloquine Lariam® Increased risk of QT prolongation Details Quinidine Metoclopramide Injection Gimoti Increased metoclopramide exposure and risk of increased adverse events Details Quinidine Metoclopramide Nasal Spray Gimoti Increased metoclopramide exposure and risk of increased adverse events Details Quinidine Metronidazole Flagyl An increased risk of QT interval prolongation Details Quinidine Metronidazole Injection Flagyl An increased risk of QT interval prolongation Details Quinidine Metronidazole Topical MetroCream® An increased risk of QT interval prolongation Details Quinidine Metronidazole Vaginal MetroGel® Vaginal An increased risk of QT interval prolongation Details Quinidine Mexiletine Mexitil® Increased mexiletine bioavailability and an increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest... Details Quinidine Mitapivat Aqvesme Reduced CYP3A substrate exposure Details Quinidine Morphine Injection Astramorph® PF Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Quinidine Moxifloxacin Avelox Increased risk of QT interval prolongation Details Quinidine Moxifloxacin Injection Avelox Increased risk of QT interval prolongation Details Quinidine Moxifloxacin Ophthalmic Moxeza® Increased risk of QT interval prolongation Details Quinidine Nebivolol Bystolic Increased exposure to nebivolol Details Quinidine Nifedipine Adalat® Increased NIFEdipine exposure and reduced quiNIDine exposure Details Quinidine Octreotide Bynfezia An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Quinidine Octreotide Injection Bynfezia An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Quinidine Ofloxacin Floxin® An increased risk of QT interval prolongation Details Quinidine Ofloxacin Ophthalmic Ocuflox An increased risk of QT interval prolongation Details Quinidine Ofloxacin Otic Floxin® Otic An increased risk of QT interval prolongation Details Quinidine Olodaterol Oral Inhalation Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details Quinidine Oxaliplatin Injection Eloxatin® Increased risk of QT-interval prolongation Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.