Ramipril

Name: Ramipril Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

64 interactions 1 explained in plain English

Also sold as: Altace Altace® Vostally

About Ramipril

Ramipril is an ACE inhibitor used to treat high blood pressure and reduce heart attack and stroke risk. Read the full Ramipril drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Aliskiren Digoxin Methotrexate Injection Melphalan Methotrexate Irbesartan

1 Contraindicated 18 Major 45 Moderate

All (64) Contraindicated (1) Major (18) Moderate (45)

Moderate

Ramipril Metformin Fortamet® An increased risk of hypoglycemia Details Ramipril Miglitol Glyset® An increased risk of hypoglycemia Details Ramipril Nabumetone Relafen Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Ramipril Naproxen Aleve Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Ramipril Nateglinide Starlix® An increased risk of hypoglycemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.