Schizandra

18 interactions 3 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Colchicine Finerenone Nifedipine Loperamide Lumateperone Methylergonovine
1 Contraindicated 14 Major 3 Moderate
All (18) Contraindicated (1) Major (14) Moderate (3)

Major

Schizandra Relugolix Orgovyx Explained Increased relugolix exposure Details Schizandra Cariprazine Vraylar Explained Increased cariprazine and its major active metabolite (didesmethylcariprazine (DDCAR)) exposure Details Schizandra Amlodipine Amvaz® Increased amLODIPine exposure and an increased risk of hypotension and edema Details Schizandra Brexpiprazole Rexulti Increased brexpiprazole exposure Details Schizandra Digoxin Cardoxin® Increased digoxin exposure Details Schizandra Dihydroergotamine Injection DHE-45® Injection Increased dihydroergotamine exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Schizandra Dihydroergotamine Nasal Spray Migranal Increased dihydroergotamine exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Schizandra Everolimus Afinitor Increased everolimus exposure Details Schizandra Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Schizandra Loperamide Diamode An increased loperamide exposure and an increased risk of loperamide-related adverse reactions Details Schizandra Lumateperone Caplyta Increased lumateperone exposure and increased risk of lumateperone-related adverse reactions Details Schizandra Methylergonovine Methergine Increased methylergonovine exposure and an increased risk of vasospasm, cerebral ischemia and/or ischemia of extremities Details Schizandra Mitapivat Aqvesme Increased mitapivat exposure Details Schizandra Nifedipine Adalat® Increased NIFEdipine exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.