Sertindole

70 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Metoclopramide Injection Metoclopramide Nasal Spray Cetirizine Ophthalmic Levofloxacin Injection Oxaliplatin Injection Goserelin Implant
2 Contraindicated 67 Major 1 Moderate
All (70) Contraindicated (2) Major (67) Moderate (1)

Contraindicated

Sertindole Metoclopramide Injection Gimoti An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Sertindole Metoclopramide Nasal Spray Gimoti An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details

Major

Sertindole Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of respiratory and CNS depression Details Sertindole Amitriptyline Elavil Explained An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Sertindole Sertraline Explained An increased risk of QT interval prolongation Details Sertindole Buprenorphine Belbuca Explained An increased risk of QT interval prolongation and an increased risk of CNS and respiratory depression Details Sertindole Relugolix Orgovyx Explained Increased risk of QT interval prolongation Details Sertindole Amisulpride Injection Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Sertindole Arsenic Trioxide Trisenox Prolongation of the QTc interval and/or torsades de pointes Details Sertindole Aripiprazole Injection Abilify An increased risk of QT interval prolongation Details Sertindole Arsenic Trioxide Injection Trisenox Prolongation of the QTc interval and/or torsades de pointes Details Sertindole Asenapine Transdermal Patch Secuado Increased risk of QT interval prolongation Details Sertindole Azithromycin AzaSite An increased risk of QT interval prolongation and torsade de pointes Details Sertindole Cabergoline Dostinex® Reduced efficacy of cabergoline and reduced efficacy of dopamine-2 receptors Details Sertindole Anagrelide Agrylin Increased risk of QT interval prolongation Details Sertindole Bedaquiline Sirturo Increased risk of QT interval prolongation Details Sertindole Butorphanol Injection Butorphic Increased risk of respiratory and CNS depression Details Sertindole Butorphanol Nasal Spray Stadol® NS Increased risk of respiratory and CNS depression Details Sertindole Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Sertindole Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Sertindole Chloroquine Aralen® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Sertindole Dasatinib Phyrago An increased risk of QT interval prolongation Details Sertindole Degarelix Injection Firmagon Increased risk of QT interval prolongation Details Sertindole Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Sertindole Diazepam Nasal Spray Valtoco Increased risk of CNS depression Details Sertindole Diazepam Rectal Diastat Increased risk of CNS depression Details Sertindole Disopyramide Norpace An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Sertindole Dofetilide Tikosyn An increased risk of QT interval prolongation, and an increased risk of torsades de pointes Details Sertindole Dolasetron Anzemet An increased risk of cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Sertindole Dolasetron Injection Anzemet An increased risk of cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Sertindole Encorafenib Braftovi Increased risk of QT interval prolongation Details Sertindole Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Sertindole Esketamine Nasal Spray Spravato Increased risk of sedation Details Sertindole Fentanyl Transdermal Patch Duragesic® Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Sertindole Flecainide Tambocor® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Sertindole Foscarnet Injection Foscavir An increased risk of cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Sertindole Fostemsavir Rukobia Increased risk of torsade de pointes Details Sertindole Gemifloxacin Factive An increased risk of cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Sertindole Glasdegib Daurismo Increased risk of QT interval prolongation Details Sertindole Goserelin Implant Zoladex Increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.