Sertindole

70 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Metoclopramide Injection Metoclopramide Nasal Spray Cetirizine Ophthalmic Levofloxacin Injection Oxaliplatin Injection Goserelin Implant
2 Contraindicated 67 Major 1 Moderate
All (70) Contraindicated (2) Major (67) Moderate (1)

Major

Sertindole Histrelin Implant Supprelin Increased risk of QT interval prolongation Details Sertindole Hydromorphone Injection Dilaudid Increased risk of respiratory and CNS depression Details Sertindole Hydromorphone Rectal available generically Increased risk of respiratory and CNS depression Details Sertindole Hydroxychloroquine Plaquenil Increased risk of QT interval prolongation Details Sertindole Inotuzumab Ozogamicin Injection Besponsa Increased risk of QT interval prolongation Details Sertindole Ivabradine Corlanor Increased risk of QT prolongation Details Sertindole Ketoconazole Topical Extina® Foam Increased risk of QT interval prolongation Details Sertindole Lacosamide Injection Motpoly An increased risk of CNS depression Details Sertindole Lefamulin Xenleta Increased risk of QT interval prolongation Details Sertindole Lenvatinib Lenvima Increased risk of QT-interval prolongation Details Sertindole Levodopa Oral Inhalation Inbrija An increased risk of CNS depression Details Sertindole Levofloxacin Levaquin Increased risk of QT interval prolongation Details Sertindole Levofloxacin Injection Levaquin Increased risk of QT interval prolongation Details Sertindole Lithium Carbonate Lithobid Weakness, dyskinesias, increased extrapyramidal symptoms, encephalopathy, and brain damage Details Sertindole Loperamide Diamode An increased risk of QT interval prolongation, which may increase risk of cardiotoxicity (torsade de pointes, cardiac arrest) Details Sertindole Mefloquine Lariam® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Sertindole Metronidazole Flagyl An increased risk of QT interval prolongation Details Sertindole Metronidazole Injection Flagyl An increased risk of QT interval prolongation Details Sertindole Metronidazole Topical MetroCream® An increased risk of QT interval prolongation Details Sertindole Metronidazole Vaginal MetroGel® Vaginal An increased risk of QT interval prolongation Details Sertindole Morphine Injection Astramorph® PF Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Sertindole Moxifloxacin Avelox Increased risk of QT interval prolongation Details Sertindole Moxifloxacin Injection Avelox Increased risk of QT interval prolongation Details Sertindole Moxifloxacin Ophthalmic Moxeza® Increased risk of QT interval prolongation Details Sertindole Nalbuphine Injection Nubain® Increased risk of respiratory and CNS depression Details Sertindole Octreotide Bynfezia An increased risk of cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Sertindole Octreotide Injection Bynfezia An increased risk of cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Sertindole Olodaterol Oral Inhalation Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details Sertindole Oxaliplatin Injection Eloxatin® Increased risk of QT-interval prolongation Details

Moderate

Sertindole Clonidine Transdermal Patch Catapres An increased risk of sedation and somnolence Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.