Simethicone

Name: Simethicone Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

1 interactions

Also sold as: Alka-Seltzer® Anti-Gas Bicarsim Colic Drops Colicon® Degas® Flatulex® Drops Gas Aide Gas Aide® Gas-X Gas-X® Genasyme® Little Tummys Maalox® Anti-Gas Majorcon® Mi-Acid Gas Relief Micon-80® Mylanta® Gas Mylaval® Mylicon Mylicon® Mytab® Gas Pepto Gas Phazyme Phazyme® SonoRx®

About Simethicone

Simethicone is an anti-gas medication used to relieve uncomfortable pressure, fullness, and bloating caused by gas. Read the full Simethicone drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

1 Moderate

All (1) Moderate (1)

Moderate

Simethicone Levothyroxine Ermeza Decreased levothyroxine efficacy Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.