Sulfinpyrazone

69 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Abrocitinib Defibrotide Injection Sertraline Fondaparinux Melphalan Injection Enoxaparin Injection
2 Contraindicated 49 Major 16 Moderate 2 Minor
All (69) Contraindicated (2) Major (49) Moderate (16) Minor (2)

Moderate

Sulfinpyrazone Acetaminophen And Codeine Capital® & Codeine Explained Increased hepatotoxicity in acetaminophen overdose Details Sulfinpyrazone Acetaminophen Acephen Increased hepatotoxicity in acetaminophen overdose Details Sulfinpyrazone Acetaminophen Injection Acephen Increased hepatotoxicity in acetaminophen overdose Details Sulfinpyrazone Acetaminophen Rectal Acephen Increased hepatotoxicity in acetaminophen overdose Details Sulfinpyrazone Aspirin Acuprin® A reduction in uricosuric effect and an increased risk of bleeding Details Sulfinpyrazone Aspirin Rectal Aspirin A reduction in uricosuric effect and an increased risk of bleeding Details Sulfinpyrazone Capsaicin Arthricare for Women Moisturizing Increased risk of bleeding Details Sulfinpyrazone Capsaicin Topical Aspercreme Warming® Increased risk of bleeding Details Sulfinpyrazone Capsaicin Transdermal Patch Aspercreme Warming® Patch Increased risk of bleeding Details Sulfinpyrazone Glimepiride Amaryl Increased blood glucose lowering effect and increased risk of hypoglycemia Details Sulfinpyrazone Hydrocortisone Ala-Cort Reduced hydrocortisone exposure Details Sulfinpyrazone Hydrocortisone Injection A-Hydrocort® Reduced hydrocortisone exposure Details Sulfinpyrazone Ibritumomab Injection Zevalin® An increased risk of bleeding and hemorrhage Details Sulfinpyrazone Icosapent Ethyl Vascepa An increased risk of bleeding Details Sulfinpyrazone Iloprost Aurlumyn Increased risk of bleeding Details Sulfinpyrazone Lecanemab-Irmb Injection Leqembi An increased risk of amyloid related imaging abnormalities or intracerebral hemorrhage Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.