Sulpiride

82 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Metoclopramide Nasal Spray Cabergoline Metoclopramide Injection Levodopa Oral Inhalation Oxaliplatin Injection Cetirizine Ophthalmic
4 Contraindicated 77 Major 1 Moderate
All (82) Contraindicated (4) Major (77) Moderate (1)

Major

Sulpiride Gatifloxacin Ophthalmic Zymar® An increased risk of QT interval prolongation Details Sulpiride Gemifloxacin Factive An increased risk of QT interval prolongation Details Sulpiride Glasdegib Daurismo Increased risk of QT interval prolongation Details Sulpiride Goserelin Implant Zoladex Increased risk of QT interval prolongation Details Sulpiride Granisetron Transdermal Patch Sancuso An increased risk of QT interval prolongation Details Sulpiride Granisetron Injection Granisol An increased risk of QT interval prolongation Details Sulpiride Histrelin Implant Supprelin Increased risk of QT interval prolongation Details Sulpiride Hydromorphone Injection Dilaudid Increased risk of respiratory and CNS depression Details Sulpiride Hydromorphone Rectal available generically Increased risk of respiratory and CNS depression Details Sulpiride Hydroxychloroquine Plaquenil An increased risk of QT interval prolongation Details Sulpiride Inotuzumab Ozogamicin Injection Besponsa Increased risk of QT interval prolongation Details Sulpiride Ivabradine Corlanor An increased risk of QT interval prolongation Details Sulpiride Ketoconazole Topical Extina® Foam An increased risk of QT interval prolongation Details Sulpiride Lacosamide Injection Motpoly An increased risk of CNS depression Details Sulpiride Lefamulin Xenleta Increased risk of QT interval prolongation Details Sulpiride Lenvatinib Lenvima Increased risk of QT-interval prolongation Details Sulpiride Levofloxacin Levaquin An increased risk of QT interval prolongation Details Sulpiride Levofloxacin Injection Levaquin An increased risk of QT interval prolongation Details Sulpiride Lithium Carbonate Lithobid Weakness, dyskinesias, increased extrapyramidal symptoms, encephalopathy, and brain damage Details Sulpiride Loperamide Diamode An increased risk of QT interval prolongation, which may increase risk of cardiotoxicity (torsade de pointes, cardiac arrest) Details Sulpiride Mefloquine Lariam® An increased risk of QT interval prolongation Details Sulpiride Metronidazole Flagyl An increased risk of QT interval prolongation Details Sulpiride Metronidazole Injection Flagyl An increased risk of QT interval prolongation Details Sulpiride Metronidazole Topical MetroCream® An increased risk of QT interval prolongation Details Sulpiride Metronidazole Vaginal MetroGel® Vaginal An increased risk of QT interval prolongation Details Sulpiride Morphine Injection Astramorph® PF Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Sulpiride Moxifloxacin Avelox An increased risk of QT interval prolongation Details Sulpiride Moxifloxacin Injection Avelox An increased risk of QT interval prolongation Details Sulpiride Moxifloxacin Ophthalmic Moxeza® An increased risk of QT interval prolongation Details Sulpiride Nalbuphine Injection Nubain® Increased risk of respiratory and CNS depression Details Sulpiride Octreotide Bynfezia An increased risk of QT interval prolongation Details Sulpiride Octreotide Injection Bynfezia An increased risk of QT interval prolongation Details Sulpiride Ofloxacin Floxin® An increased risk of QT interval prolongation Details Sulpiride Ofloxacin Ophthalmic Ocuflox An increased risk of QT interval prolongation Details Sulpiride Ofloxacin Otic Floxin® Otic An increased risk of QT interval prolongation Details Sulpiride Olodaterol Oral Inhalation Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details Sulpiride Oxaliplatin Injection Eloxatin® Increased risk of QT-interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.