Thalidomide

Name: Thalidomide Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

8 interactions

Also sold as: Thalomid Thalomid®

About Thalidomide

Thalidomide is used along with dexamethasone to treat multiple myeloma in people who have been recently found to have this disease. It is also used alone or with other medications to treat and prevent skin symptoms of erythema nodosum leprosum (ENL; episodes of skin sores, fever, and nerve damage that occur in people w… Read the full Thalidomide drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Dexamethasone Injection Dexamethasone Ophthalmic Docetaxel Docetaxel Injection

4 Major 4 Moderate

All (8) Major (4) Moderate (4)

Moderate

Thalidomide Cyclosporine Injection Atopica Increased cycloSPORINE A metabolism and clearance Details Thalidomide Cyclosporine Ophthalmic Cequa Increased cycloSPORINE A metabolism and clearance Details Thalidomide Midazolam Nasal Spray Nayzilam Increased midazolam metabolism and clearance Details Thalidomide Midazolam Injection Nayzilam Increased midazolam metabolism and clearance Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.