Tiaprofenic Acid

91 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketorolac Ophthalmic Ketorolac Ketorolac Nasal Spray Ketorolac Injection Melphalan Injection Pemetrexed Injection
4 Contraindicated 59 Major 28 Moderate
All (91) Contraindicated (4) Major (59) Moderate (28)

Moderate

Tiaprofenic Acid Lisinopril Prinivil Explained Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Tiaprofenic Acid Atenolol Tenormin Explained Reduced antihypertensive effect Details Tiaprofenic Acid Acebutolol Sectral® Reduced antihypertensive effect Details Tiaprofenic Acid Benazepril Lotensin Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Tiaprofenic Acid Azilsartan Edarbi Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Tiaprofenic Acid Betaxolol Betoptic S Reduced antihypertensive effect Details Tiaprofenic Acid Betaxolol Ophthalmic Betoptic® Reduced antihypertensive effect Details Tiaprofenic Acid Bisoprolol Zebeta® Reduced antihypertensive effect Details Tiaprofenic Acid Captopril Capoten® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Tiaprofenic Acid Desmopressin Nasal Concentraid® Increased risk of water intoxication with hyponatremia Details Tiaprofenic Acid Enalapril Epaned Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Tiaprofenic Acid Eprosartan Teveten® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Tiaprofenic Acid Esmolol Brevibloc Reduced antihypertensive effect Details Tiaprofenic Acid Fosinopril Monopril® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Tiaprofenic Acid Irbesartan Avapro Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Tiaprofenic Acid Labetalol Normodyne® Reduced antihypertensive effect Details Tiaprofenic Acid Levobunolol Ophthalmic AKBeta® Reduced antihypertensive effect Details Tiaprofenic Acid Levofloxacin Levaquin An increased risk of seizures Details Tiaprofenic Acid Levofloxacin Injection Levaquin An increased risk of seizures Details Tiaprofenic Acid Losartan Arbli Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Tiaprofenic Acid Moexipril Univasc® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Tiaprofenic Acid Nadolol Corgard Reduced antihypertensive effect Details Tiaprofenic Acid Nebivolol Bystolic Reduced antihypertensive effect Details Tiaprofenic Acid Ofloxacin Floxin® An increased risk of seizures Details Tiaprofenic Acid Ofloxacin Ophthalmic Ocuflox An increased risk of seizures Details Tiaprofenic Acid Ofloxacin Otic Floxin® Otic An increased risk of seizures Details Tiaprofenic Acid Penbutolol Levatol® Reduced antihypertensive effect Details Tiaprofenic Acid Perindopril Aceon Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.