Timolol

Name: Timolol Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

60 interactions 3 explained in plain English

Also sold as: Betimol Blocadren® Istalol Timoptic

About Timolol

Timolol is a beta blocker used to treat high blood pressure, prevent migraines, and improve survival after a heart attack. Read the full Timolol drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Sertraline Albuterol Oral Inhalation Abiraterone Clonidine Transdermal Patch Indacaterol Oral Inhalation Lacosamide Injection

8 Major 52 Moderate

All (60) Major (8) Moderate (52)

Moderate

Timolol Meclofenamate Meclodium® Reduced antihypertensive effect Details Timolol Mefenamic Acid Ponstel® Reduced antihypertensive effect Details Timolol Meloxicam Alloxate Reduced antihypertensive effect Details Timolol Meloxicam Injection Alloxate Reduced antihypertensive effect Details Timolol Metformin Fortamet® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Timolol Methimazole Felanorm Altered metabolism of the beta-adrenergic blocker Details Timolol Methyldopa Aldomet® Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Timolol Miglitol Glyset® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Timolol Nabumetone Relafen Reduced antihypertensive effect Details Timolol Naproxen Aleve Reduced antihypertensive effect Details Timolol Nateglinide Starlix® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Timolol Nifedipine Adalat® An increased risk of congestive heart failure, severe hypotension or exacerbation of angina Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.