ChloraPrep Generic: When Will It Be Available?
This page is aggregated from FDA records, court filings and company announcements. Coded and designed by Dr. Brian Staiger, PharmD, BCPS
Updated October 9, 2026 How we build our data
ChloraPrep Generic at a Glance
Four quick answers from FDA records and our estimate.
- When is the first generic expected? TBD no date yet What opens the door is not settled yet
- Has the FDA approved a generic? Unknown No FDA Orange Book record under this name
- When does the brand’s protection end? Unknown Not in the FDA record we could read
- Can you buy a generic today? Not yet No company lists one for sale
There is no expected month yet for generic chlorhexidine gluconate and isopropyl alcohol. None is for sale yet.
Will the generic cost less?
Usually, but no company is recorded as having applied to make one yet, and a single company usually brings only a modest drop. See the price pattern
What should I do now?
Keep taking ChloraPrep as prescribed. When a generic arrives, your pharmacy may switch you to it automatically, and it may look different. What a generic means for you
Our month is only an estimate based on available information, so we never name a day.
ChloraPrep by the Numbers
- Reason
- Not yet clearNo generic application is on record yet. The month follows the patents and protections on record, which a challenge or a deal can end early.
- How sure
- Not rated Too early to rate.
- Price competition
- None filed yet No filers on record
- Brand sales
- Sales not reported
Who Is Lined Up to Make Generic Chlorhexidine Gluconate and Isopropyl Alcohol
Three steps stand between a brand and a generic you can buy: a company applies to the FDA, the FDA approves it, and the company starts selling it.
Applied to the FDA
No company is recorded as having applied to the FDA to make a generic ChloraPrep yet.
Approved by the FDA
We could not find ChloraPrep’s own record in the FDA Orange Book under this name, so the approved generic makers are not shown.
For Sale in Pharmacies
Not yet. No company lists a generic chlorhexidine gluconate and isopropyl alcohol for sale with the FDA.
Sources: how many companies have applied, from court records and company announcements; approved generics from the FDA Orange Book; what is for sale from the FDA NDC Directory. The FDA does not disclose an application before it approves it (21 CFR 314.430).
ChloraPrep Price: What Pharmacies Pay and What Generics Usually Do
What a Generic Could Cost
How we estimate it. The national survey of what pharmacies pay (NADAC) has no recent price for ChloraPrep, so we cannot show dollars. Here is the FDA’s finding of how far the price pharmacies pay usually falls as generic companies join: about 31% with one company, 44% with two, 73% with four and over 95% with six or more (the typical drop for every drug whose first generic came out from 2015 to 2017).
Median prices pharmacies paid for the generic (invoice prices), compared with the brand’s price before generic entry, from FDA’s 2019 analysis “Generic Competition and Drug Prices”. At the manufacturer’s price FDA found steeper drops (about 39%, 54%, 79% and over 95%), the figures quoted elsewhere on this tracker. A typical pattern, not a price quote for this medicine.
ChloraPrep NDC Codes and Packages
Each ChloraPrep package sold today has its own NDC, the product number printed on the box and on the pharmacy label. Open one to see that package’s details, what pharmacies pay for it and its patent timeline.
| NDC | Product | Package | Company |
|---|---|---|---|
| 51662-1675-01 | ISOPROPYL ALCOHOL .7 mL/mL / CHLORHEXIDINE GLUCONATE 20 mg/mL solution | applicator of 1.75 mL | HF Acquisition Co LLC, DBA HealthFirst |
Source: the FDA NDC Directory, current listings only. Some codes belong to companies that repackage ChloraPrep: it is the same medicine in a different package.
What a Generic ChloraPrep Means for You
Nothing Changes Until It Is in Pharmacies
Until a generic is actually for sale, keep filling ChloraPrep as usual. When one arrives, there is nothing you need to sign up for.
Your Pharmacy May Switch You Automatically
Every state lets pharmacists fill a brand-name prescription with an FDA-approved generic rated as equivalent to it, and about 19 states require them to, unless your prescriber writes “dispense as written” or “brand medically necessary” on the prescription. Some states ask the pharmacist to tell you, or to get your OK first. A study of every state’s law has the details.
It Will Probably Look Different
US trademark law does not let a generic look exactly like the brand, so the color, shape or markings usually change. The active ingredient, strength and form are the same. An “authorized generic,” made by or for the brand’s own company, can look identical. The FDA explains.
Your Insurance May Change Too
Once a lower-cost version is available, many insurance plans charge more for the brand, or stop covering it. Your plan’s drug list (formulary) says how.
Until a generic is on US pharmacy shelves, be careful with websites that offer “generic ChloraPrep”. The FDA warns that unlicensed online pharmacies sell counterfeit and unapproved medicines; its BeSafeRx page shows how to check a pharmacy.
Questions people ask about ChloraPrep
Is there a generic for ChloraPrep right now?
No. As of October 9, 2026 no generic chlorhexidine gluconate and isopropyl alcohol is listed for sale in the FDA NDC Directory.
When will ChloraPrep go generic?
There is no expected month yet. No generic application is on record yet. The month follows the patents and protections on record, which a challenge or a deal can end early.
Will generic chlorhexidine gluconate and isopropyl alcohol be the same as ChloraPrep?
Yes in the ways that matter: the same active ingredient, strength and form, with proof that it reaches your blood the same way. Inactive ingredients can differ, which is why some people notice a different look or taste.
How much will the generic cost?
Nobody can say for sure before launch. No company is recorded as having applied to the FDA to make one yet, and a single company usually brings only a modest drop.
Changes to This Projection
- First generic expected a date that is not known yet on this month’s schedule. A line is added here whenever a monthly update moves the month, the reason or how sure it is.
Every change to the expected month is logged here with the month we saw it.
Also Going Generic
- VyondysGolodirsenJune 2028
- JubliaEfinaconazole2030 to 2031
- Spy Agent GreenIndocyanine Green2030 to 2031
- OpsynviMacitentan and TadalafilSeptember 2031
- AsteproAzelastine HydrochlorideTBD no date yet
- EmendAprepitantTBD no date yet
About ChloraPrep
- Generic name chlorhexidine gluconate and isopropyl alcohol
- How it is taken On the skin
- More drugs Brand-name drugs starting with C
- Have a question? A pharmacist answers, free. Ask about ChloraPrep
Sources. The expected month: FDA Paragraph IV Patent Certifications list, federal court records, company announcements and securities filings (settlement dates, launch plans, sales). The record on this page: FDA Orange Book, FDA NDC Directory, FDA, Generic Competition and Drug Prices (2019). Updated October 9, 2026. Information, not medical advice.