Olinvyk Generic: When Will Generic Oliceridine Be Available?

This page is aggregated from FDA records, court filings and company announcements. Coded and designed by Dr. Brian Staiger, PharmD, BCPS

Updated October 9, 2026 How we build our data

Olinvyk Generic at a Glance

Four quick answers from FDA records and our estimate.

When is the first generic expected? October 2034 About 8 years away Why then?
Has the FDA approved a generic? Not yet None in the FDA’s records yet Why not yet?
When does the brand’s protection end? March 2032 The last of 5 listed patents
Can you buy a generic today? Not yet No company lists one for sale

Dr. Brian Staiger Explains

PharmD, BCPS · Clinical pharmacist

Generic oliceridine is expected to be available in October 2034, about 8 years away. None is for sale yet.

Why October 2034?

It is when Olinvyk’s patent 9,309,234 ends. That patent covers the active ingredient, the product’s formulation and a way of using it, and once it ends, generics can go on sale as soon as the FDA approves them. We rate it probable: more likely than not, but it can still move.

Why hasn’t the FDA approved a generic yet?

That is normal before a launch. The FDA usually can’t give a generic its final approval while a patent or exclusivity still blocks it, so final approval often comes close to the day the generic can be sold. No company holds a “tentative” approval yet either (the FDA’s word for a generic that is ready but still blocked).

Will the generic cost less?

Usually, but no company is recorded as having applied to make one yet, and a single company usually brings only a modest drop. See the price pattern

What should I do now?

Keep taking Olinvyk as prescribed. When a generic arrives, your pharmacy may switch you to it automatically, and it may look different. What a generic means for you

Our month is only an estimate based on available information, so we never name a day.

Olinvyk by the Numbers

Reason: Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure: Probable More likely than not, but it can still move.
Price competition: None filed yet No filers on record
Brand sales: Sales not reported

FDA approved 2020 October 2020 FDA Orange Book
Patents listed 5 last runs to March 2032 FDA Orange Book

Olinvyk’s Road to a Generic

Olinvyk has had the market to itself since the FDA approved it in October 2020 (Trevena Inc). Its 5 listed patents run to March 2032.

The first generic of Olinvyk is expected in October 2034.

Why that month: patent 9,309,234, on the active ingredient, the product’s formulation and a way of using it, ends then.

Brand alone on the market Since FDA approval, October 2020

Patent 8,835,488 Expires March 2032

Patent 9,309,234 Expires March 2032 The patent behind the expected month of generic availability

Patent 9,642,842 Expires March 2032

Patent 11,077,098 Expires March 2032

Patent 11,931,350 Expires March 2032

Brand alone on the market Patent on the active ingredient Patent on the formulation First generic expected Swipe the chart sideways to see every year.

Each bar runs from the brand’s approval to the day that protection ends. The green band is our projection for the first generic: a month, never a day, because legal dates move and a generic reaches shelves days to weeks after it is allowed. Sources: FDA Orange Book; the expected month from court records and company announcements.

Olinvyk Patents and FDA Protections

Every patent and exclusivity the FDA Orange Book lists for Olinvyk’s own applications. A protection running past the expected month does not mean the date is wrong: a settlement or a court ruling can let a generic in before a patent ends, and a patent on one formulation or use does not block every generic.

The one that matters for a generic launch: patent 9,309,234, which ends in March 2032; the first generic is expected after it, in October 2034, about 8 years away.

Patents listed with the FDA (5)
Patent	What it covers	Protects until	Status
8,835,488	The active ingredient; the product’s formulation; a way of using it (U-2986)	March 2032	Active
9,309,234 Sets the expected month of generic availability	The active ingredient; the product’s formulation; a way of using it (U-2986)	March 2032	Active
9,642,842	The product’s formulation; a way of using it (U-2986)	March 2032	Active
11,077,098	The active ingredient; the product’s formulation; a way of using it (U-2986)	March 2032	Active
11,931,350	The active ingredient; a way of using it (U-2986)	March 2032	Active

Source: FDA Orange Book, application 210730. Patent numbers open the patent on Google Patents.

Who Is Lined Up to Make Generic Oliceridine

Three steps stand between a brand and a generic you can buy: a company applies to the FDA, the FDA approves it, and the company starts selling it.

Applied to the FDA

No company is recorded as having applied to the FDA to make a generic Olinvyk yet.

Approved by the FDA

Not yet. The FDA has not approved a generic oliceridine. Final approval often comes close to the day a generic can be sold.

For Sale in Pharmacies

Not yet. No company lists a generic oliceridine for sale with the FDA.

Sources: how many companies have applied, from court records and company announcements; approved generics from the FDA Orange Book; tentative approvals from Drugs@FDA; what is for sale from the FDA NDC Directory. The FDA does not disclose an application before it approves it (21 CFR 314.430).

Olinvyk Price: What Pharmacies Pay and What Generics Usually Do

What a Generic Could Cost

How we estimate it. The national survey of what pharmacies pay (NADAC) has no recent price for Olinvyk, so we cannot show dollars. Here is the FDA’s finding of how far the price pharmacies pay usually falls as generic companies join: about 31% with one company, 44% with two, 73% with four and over 95% with six or more (the typical drop for every drug whose first generic came out from 2015 to 2017).

Brandbefore generics

1 makerabout 31% less

2 makersabout 44% less

4 makersabout 73% less

6+ makersover 95% less

Median prices pharmacies paid for the generic (invoice prices), compared with the brand’s price before generic entry, from FDA’s 2019 analysis “Generic Competition and Drug Prices”. At the manufacturer’s price FDA found steeper drops (about 39%, 54%, 79% and over 95%), the figures quoted elsewhere on this tracker. A typical pattern, not a price quote for this medicine.

Olinvyk Strengths and Forms

Strength	Form	How it is taken	Approved	Status
1MG/ML (1MG/ML)	Solution	Intravenous	October 2020	Discontinued reference product
2MG/2ML (1MG/ML)	Solution	Intravenous	October 2020	Discontinued reference product
30MG/30ML (1MG/ML)	Solution	Intravenous	October 2020	Discontinued reference product

Source: FDA Orange Book, Trevena Inc. Listed for sale today by Trevena, Inc. (FDA NDC Directory).

Olinvyk NDC Codes and Packages

Each Olinvyk package sold today has its own NDC, the product number printed on the box and on the pharmacy label. Open one to see that package’s details, what pharmacies pay for it and its patent timeline.

Olinvyk packages (5)
NDC	Product	Package	Company
71308-0301-10	30 mg/30mL injection, solution	carton of 10 vials of 30 mL	Trevena, Inc.
71308-0011-10	OLICERIDINE 1 mg/mL injection, solution	carton of 10 vials of 1 mL	Trevena, Inc.
71308-0011-10	OLICERIDINE 1 mg/mL injection, solution	carton of 10 vials of 1 mL	Trevena, Inc.
71308-0021-10	OLICERIDINE 2 mg/2mL injection, solution	carton of 10 vials of 2 mL	Trevena, Inc.
71308-0021-10	OLICERIDINE 2 mg/2mL injection, solution	carton of 10 vials of 2 mL	Trevena, Inc.

Source: the FDA NDC Directory, current listings only. Only packages sold under Olinvyk’s own FDA approval (NDA 210730) are listed, never a generic. Some codes belong to companies that repackage Olinvyk: it is the same medicine in a different package.

What a Generic Olinvyk Means for You

Nothing Changes Until It Is in Pharmacies

Until a generic is actually for sale, keep filling Olinvyk as usual. When one arrives, there is nothing you need to sign up for.

Your Pharmacy May Switch You Automatically

Every state lets pharmacists fill a brand-name prescription with an FDA-approved generic rated as equivalent to it, and about 19 states require them to, unless your prescriber writes “dispense as written” or “brand medically necessary” on the prescription. Some states ask the pharmacist to tell you, or to get your OK first. A study of every state’s law has the details.

It Will Probably Look Different

US trademark law does not let a generic look exactly like the brand, so the color, shape or markings usually change. The active ingredient, strength and form are the same. An “authorized generic,” made by or for the brand’s own company, can look identical. The FDA explains.

Your Insurance May Change Too

Once a lower-cost version is available, many insurance plans charge more for the brand, or stop covering it. Your plan’s drug list (formulary) says how.

Until a generic is on US pharmacy shelves, be careful with websites that offer “generic Olinvyk”. The FDA warns that unlicensed online pharmacies sell counterfeit and unapproved medicines; its BeSafeRx page shows how to check a pharmacy.

Ask a pharmacist about Olinvyk

Questions people ask about Olinvyk

Is there a generic for Olinvyk right now?

No. As of October 9, 2026 no generic oliceridine is listed for sale in the FDA NDC Directory.

When will Olinvyk go generic?

October 2034 is the expected month, and that is probable but not certain. It is when Olinvyk’s patent 9,309,234 ends. That patent covers the active ingredient, the product’s formulation and a way of using it, and once it ends, generics can go on sale as soon as the FDA approves them.

Will generic oliceridine be the same as Olinvyk?

Yes in the ways that matter: the same active ingredient, strength and form, with proof that it reaches your blood the same way. Inactive ingredients can differ, which is why some people notice a different look or taste.

How much will the generic cost?

Nobody can say for sure before launch. No company is recorded as having applied to the FDA to make one yet, and a single company usually brings only a modest drop.

Has the FDA approved a generic Olinvyk?

Not yet. The FDA Orange Book lists no approved generic version of Olinvyk.

When does the Olinvyk patent expire?

The FDA Orange Book lists 5 patents for Olinvyk; the last runs to March 2032. The one behind the expected month is patent 9,309,234, which ends in March 2032. A patent date is not the launch date: settlements and court rulings often bring a generic earlier, and FDA approval or a company’s own plans can make it later. The expected month on this page (October 2034) weighs all of that.

Changes to This Projection

October 2026First generic expected October 2034 on this month’s schedule. A line is added here whenever a monthly update moves the month, the reason or how sure it is.

Every change to the expected month is logged here with the month we saw it.

Also Going Generic

All upcoming generics

About Olinvyk

Generic name oliceridine
How it is taken Into a vein (IV)
Company Trevena Inc
Hard to copy Inhalers, injectables, patches and other hard-to-copy products. Fewer companies attempt them and dates slip more often.
More drugs Brand-name drugs starting with O
Have a question? A pharmacist answers, free. Ask about Olinvyk

Sources. The expected month: FDA Paragraph IV Patent Certifications list, federal court records, company announcements and securities filings (settlement dates, launch plans, sales). The record on this page: FDA Orange Book, Drugs@FDA (tentative approvals), FDA NDC Directory, FDA, Generic Competition and Drug Prices (2019). Updated October 9, 2026. Information, not medical advice.