Drug & supplement interaction

Ajuga Nipponensis + Daratumumab

Daratumumab brand name: Darzalex.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Ajuga Nipponensis and Daratumumab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Ajuga Nipponensis and Daratumumab

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Daratumumab and Ajuga Nipponensis in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Ajuga Nipponensis at all — not against Daratumumab, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Ajuga Nipponensis safety at a glance

Ajuga Nipponensis overall Not established There is not enough reliable human data to judge its safety.
Pregnancy Avoid Safety has not been studied, so it is best avoided during pregnancy.
Breastfeeding Avoid No safety data exists for breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Daratumumab and Ajuga Nipponensis? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Ajuga Nipponensis and Daratumumab May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Diarrhea / Nausea reported in 4.4% of FDA reports for Daratumumab Additional detail

    Ajuga Nipponensis

    “Orally, Ajuga nipponensis has been reported to cause diarrhea, nausea, and vomiting.”

    Ajuga Nipponensis · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 14070. Liao SC, Chiu TF, Chen JC, Lin CC. Ajuga nipponensis Makino poisoning. Clin Toxicol (Phila) 2005;43:583-5.

    Daratumumab

    Listed in the ADVERSE REACTIONS section of the FDA label for Daratumumab, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

Reported for Ajuga Nipponensis but not commonly for Daratumumab: kidney problems and vomiting.

Effects for Daratumumab come from the ADVERSE REACTIONS section of its FDA label; effects for Ajuga Nipponensis come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 42,488 voluntary FDA FAERS reports for Daratumumab that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

How much people look this up

Where Ajuga Nipponensis and Daratumumab Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Ajuga Nipponensis
Steady interest

#1,241 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Daratumumab
Steady interest

#2,063 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Ajuga Nipponensis reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Ajuga Nipponensis and Daratumumab records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Ajuga Nipponensis

What is Ajuga Nipponensis?

Ajuga Nipponensis
  • Cough and respiratory symptoms
  • Sore throat
  • Fever
  • Inflammation
  • Traditional general wellness

Ajuga nipponensis is a perennial plant from East Asia used in traditional medicine for cough and respiratory complaints. There is very little human research to confirm any health benefits, so its effectiveness and safety remain largely unknown. Talk to a pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or taking other medicines.

Ajuga nipponensis · Lamiaceae · Whole plant, leaves, and aerial parts · Dried herb, tea, traditional decoctions, extracts

An interaction check asks whether these two react with each other — it does not ask whether Ajuga Nipponensis is a good idea for someone in your situation. Here is what our Ajuga Nipponensis record says about it on its own.

Ajuga Nipponensis: dosing

There is no established or standardized dose for Ajuga nipponensis. Scientists have not determined a safe and effective amount for any condition.If you choose to use a product that contains it, follow the directions on the label and do not exceed them.

From our Ajuga Nipponensis monograph — the full record covers uses, side effects and every documented interaction.

Read the full Ajuga Nipponensis monograph & all interactions
Medication

About Daratumumab Injection

What Is Daratumumab Injection Used For?

Brand name: Darzalex

Darzalex is used to treat adult patients with multiple myeloma (a cancer of plasma cells in the bone marrow). It is used in several different settings: for people newly diagnosed who cannot have a stem cell transplant, for those who are eligible for a stem cell transplant, and for those whose myeloma has come back or stopped responding to earlier treatments.

Darzalex can be used alone or in combination with other medicines such as lenalidomide, bortezomib, pomalidomide, carfilzomib, thalidomide, melphalan, prednisone, and/or dexamethasone. The specific combination depends on where a patient is in their treatment journey and which prior therapies they have received.

Most-Reported Side Effects for Daratumumab

From FAERS, the FDA’s public side-effect reporting system (42,488 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Plasma cell myeloma 3,971 reports
Infusion related reaction 2,703 reports
Pneumonia 2,104 reports
Neutropenia 2,097 reports
Fatigue 1,962 reports
See full Daratumumab Injection drug information
Keep checking

Other Drugs & Ajuga Nipponensis

Browse every other medication we’ve checked against Ajuga Nipponensis — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Ajuga Nipponensis against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Ajuga Nipponensis list.

See the full Ajuga Nipponensis interactions page
See every supplement checked against Daratumumab, ranked by severity
Evidence & sources

Ajuga Nipponensis References

The 1 references that drive our Ajuga Nipponensis monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Liao SC, Chiu TF, Chen JC, Lin CC. Ajuga nipponensis Makino poisoning. Clin Toxicol (Phila) 2005;43:583-5.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Ajuga Nipponensis and Daratumumab Together: Common Questions

Is it safe to take Ajuga Nipponensis with Daratumumab?
We do not list a known interaction between Ajuga Nipponensis and Daratumumab. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Ajuga Nipponensis and Daratumumab have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Ajuga Nipponensis monograph Uses, safety profile, and every drug interaction in one place Daratumumab Injection drug information The full plain-English guide to this medication Daratumumab supplement interactions Every supplement checked against Daratumumab, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Daratumumab and Ajuga Nipponensis?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.