Drug & supplement interaction

American Adder's Tongue + Sargramostim

Sargramostim brand name: Leukine.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between American Adder's Tongue and Sargramostim in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

American Adder's Tongue and Sargramostim

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Sargramostim and American Adder's Tongue in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for American Adder's Tongue at all — not against Sargramostim, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

American Adder's Tongue safety at a glance

American Adder's T... overall Use caution Human safety data is very limited, and the plant can cause stomach upset or vomiting when eaten.
Pregnancy Avoid There is not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid There is not enough safety information, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Sargramostim and American Adder's Tongue? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Sargramostim’s Own FDA Label Lists

This is not an interaction — none of it involves American Adder's Tongue. These are the most notable effects listed in the ADVERSE REACTIONS section of Sargramostim’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Low magnesium Worth acting on
  • Trouble swallowing Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • High blood sugar Worth acting on
  • Fainting Worth acting on
  • Shortness of breath Worth acting on mentioned in 6.6% of FDA reports for Sargramostim
  • Chest pain Worth acting on
  • A low platelet count Worth acting on
  • Kidney problems Worth acting on
  • Anemia Worth acting on

Showing the 10 most notable of 45 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Sargramostim. Read the label on DailyMed › Where a percentage is shown, it is the share of 1,675 voluntary FDA FAERS reports for Sargramostim that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. American Adder's Tongue’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no American Adder's Tongue side to compare — that is a limit of the record, not a statement that American Adder's Tongue has no side effects.

How much people look this up

Where American Adder's Tongue and Sargramostim Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement American Adder's Tongue
Steady interest

#1,420 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Sargramostim
Top half

#955 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. American Adder's Tongue is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every American Adder's Tongue reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The American Adder's Tongue and Sargramostim records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About American Adder's Tongue

What is American Adder's Tongue?

American Adder's Tongue
  • Skin ulcers and wounds
  • Swollen glands
  • Minor skin irritation
  • Folk remedy for nausea (as an emetic)

American Adder's Tongue (Erythronium americanum) is a woodland lily used in traditional folk medicine, mainly as a crushed-leaf poultice for skin ulcers and wounds. There is very little modern scientific evidence to support any of its uses, and safety information is limited, so it should be used cautiously and avoided in pregnancy and breastfeeding.

Erythronium americanum · Liliaceae · Leaves and tubers (corms) · Crushed fresh leaves (poultice), juice, tea, tincture

An interaction check asks whether these two react with each other — it does not ask whether American Adder's Tongue is a good idea for someone in your situation. Here is what our American Adder's Tongue record says about it on its own.

American Adder's Tongue: dosing

There is no established or standardized dose for American Adder's Tongue. Because it has not been studied in modern clinical research, no safe and effective amount has been identified.If a product is sold commercially, follow the directions on the label and do not exceed them. Avoid eating raw leaves or corms, as this can cause vomiting.

From our American Adder's Tongue monograph — the full record covers uses, side effects and every documented interaction.

Read the full American Adder's Tongue monograph & all interactions
Medication

About Sargramostim

What Is Sargramostim Used For?

Brand name: Leukine

Leukine (sargramostim) is used in several serious medical situations where the body's white blood cell production has been knocked down. It is approved to speed up the recovery of infection-fighting neutrophils after chemotherapy for acute myeloid leukemia (AML) in adults 55 and older, and to help bone marrow recover after autologous or allogeneic bone marrow transplants in adults and children aged 2 and older.

Leukine is also used to mobilize stem cells from bone marrow into the bloodstream so they can be collected before an autologous transplant, and to treat delayed or failed bone marrow recovery after transplant. Additionally, Leukine is approved to improve survival in adults and children (from birth through age 17) who have been exposed to dangerously high doses of radiation (a condition called Hematopoietic Syndrome of Acute Radiation Syndrome, or H-ARS).

Most-Reported Side Effects for Sargramostim

From FAERS, the FDA’s public side-effect reporting system (1,675 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fever 153 reports
Nausea 118 reports
Dyspnea 110 reports
Hypotension 110 reports
Fatigue 94 reports
See full Sargramostim drug information
Keep checking

Other Drugs & American Adder's Tongue

Browse every other medication we’ve checked against American Adder's Tongue — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked American Adder's Tongue against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full American Adder's Tongue list.

See the full American Adder's Tongue interactions page
See every supplement checked against Sargramostim, ranked by severity
Evidence & sources

American Adder's Tongue References

The 2 sources that drive our American Adder's Tongue monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. American Adder's Tongue is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  2. Using Dietary Supplements Wisely — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking American Adder's Tongue and Sargramostim Together: Common Questions

Is it safe to take American Adder's Tongue with Sargramostim?
We do not list a known interaction between American Adder's Tongue and Sargramostim. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

American Adder's Tongue monograph Uses, safety profile, and every drug interaction in one place Sargramostim drug information The full plain-English guide to this medication Sargramostim supplement interactions Every supplement checked against Sargramostim, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Sargramostim and American Adder's Tongue?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.