Androstenetrione + Disulfiram
Disulfiram brand name: Antabuse.
We found no known interaction between Androstenetrione and Disulfiram in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Androstenetrione and Disulfiram
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Disulfiram and Androstenetrione in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Androstenetrione safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Disulfiram
Interactions in our licensed database are recorded against drug classes, not just single drug names. Disulfiram is filed under 4 classifications — including cytochrome p450 2c9 (cyp2c9) inhibitors, seizure threshold lowering drugs, oral drugs. Androstenetrione has documented interactions with 1 drug class — the most serious being androgens (minor) — and none of Disulfiram’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Androstenetrione Does Interact With Other Medications
Androstenetrione has 9 minor known drug interactions in our database — Disulfiram isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Androstenetrione
We haven’t checked that one against Androstenetrione yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Androstenetrione. Pick one to open its full report.
Androstenetrione in Pregnancy & Breastfeeding
When used orally. There is no scientifically reliable information about using androstenetrione during pregnancy or lactation. Promoters indicate that it can increase testosterone levels. If this is true, this product may not be safe due to the adverse effects associated with elevated testosterone levels; avoid using.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
Questions About Androstenetrione or Disulfiram
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Androstenetrione or Disulfiram, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Disulfiram
This page covers Androstenetrione only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Disulfiram page lists 45 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Bach Flower Remedies (major), Beer (major), Wine (major) and Biofeedback (moderate).
By severity: 4 major · 30 moderate · 11 minor.
Taking Androstenetrione as Part of a Dietary Supplement Product? Check It for Interactions
We hold 2 real supplement products containing Androstenetrione, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Androstenetrione. Even though Androstenetrione itself has no known interaction with Disulfiram, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Androstenetrione and Disulfiram Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,104 of 1,452 supplements looked up here in the last 7 days
#1,304 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Androstenetrione is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Androstenetrione reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Androstenetrione and Disulfiram records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Androstenetrione
What is Androstenetrione?
- Boosting testosterone
- Lowering estrogen
- Bodybuilding and muscle building
- Post-cycle support for steroid users
- Athletic performance
Androstenetrione (6-OXO) is a synthetic compound marketed to raise testosterone by blocking the enzyme that turns testosterone into estrogen. Solid human evidence that it offers real benefits is lacking, and it can cause hormone-related side effects, so most people should avoid it and talk with a healthcare provider first.
Synthetic compound (not from a plant) · Capsules, tablets
An interaction check asks whether these two react with each other — it does not ask whether Androstenetrione is a good idea for someone in your situation. Here is what our Androstenetrione record says about it on its own.
Androstenetrione: dosing
There is no established, standardized dose for androstenetrione, and no dose has been proven safe and effective. Different products contain different amounts.Because of the hormone-related risks and weak evidence, we cannot recommend a specific amount.
From our Androstenetrione monograph — the full record covers uses, side effects and every documented interaction.
About Disulfiram
What Is Disulfiram Used For?
Brand name: Antabuse
Disulfiram is used as part of a treatment program for people with chronic alcoholism who want to stop drinking. It works by making the body react very unpleasantly to alcohol, which helps reinforce the commitment to stay sober.
It is not a cure for alcoholism, and it works best when combined with counseling, motivation, and support. Used alone, without those supports, it is unlikely to make a lasting difference.
Most-Reported Side Effects for Disulfiram
From FAERS, the FDA’s public side-effect reporting system (1,124 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Androstenetrione
Browse every other medication we’ve checked against Androstenetrione — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
9 interactions
No interaction 2,820 drugs checked — show the list
We also checked Androstenetrione against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Warfarin ›
- Methylphenidate ›
- Sertraline ›
- Ivermectin ›
- Losartan Potassium ›
- Abemaciclib ›
- Aspirin ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Tadalafil ›
- Tirzepatide ›
- Methamphetamine ›
- Ibuprofen ›
- Warfarin Sodium ›
- Valacyclovir ›
- Hydroxyurea ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Propranolol ›
- Amitriptyline ›
- Lisdexamfetamine ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Amlodipine Besylate ›
- Bendamustine ›
- Methotrexate ›
- Bupropion ›
- Amphetamine ›
- Doxycycline ›
- Fluoxetine ›
- Azithromycin ›
- Acyclovir ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Levothyroxine, Liothyronine ›
- Clonazepam ›
- Quetiapine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Duloxetine ›
- Methylene Blue ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
Showing the 60 most looked-up of 2,820 medications checked with no known interaction — see the full Androstenetrione list.
Androstenetrione References
The 3 sources that drive our Androstenetrione monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Androstenetrione is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.
- Dietary Supplements for Exercise and Athletic Performance — NIH Office of Dietary Supplements Source
- Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
- Herbs at a Glance — NIH NCCIH Source
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Disulfiram Is Linked to Lower Levels of One Nutrient
Natural Medicines records Disulfiram as a medicine that can lower these. This is not an interaction with Androstenetrione — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Disulfiram nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Androstenetrione and Disulfiram Together: Common Questions
Is it safe to take Androstenetrione with Disulfiram?
How was the Androstenetrione and Disulfiram combination checked?
Does Androstenetrione interact with any other medications?
Does Disulfiram interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Disulfiram and Androstenetrione?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.