Drug & supplement interaction

Arenaria Rubra + Elbasvir, Grazoprevir

Elbasvir, Grazoprevir brand name: Zepatier.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Arenaria Rubra and Elbasvir, Grazoprevir in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Arenaria Rubra and Elbasvir, Grazoprevir

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Elbasvir, Grazoprevir and Arenaria Rubra in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Arenaria Rubra safety at a glance

Arenaria Rubra overall Not established Human safety data are very limited, so use cautiously and under professional guidance.
Pregnancy Avoid There is not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid Safety while breastfeeding is unknown, so avoid use to be safe.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Elbasvir, Grazoprevir and Arenaria Rubra? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Elbasvir, Grazoprevir

Interactions in our licensed database are recorded against drug classes, not just single drug names. Elbasvir, Grazoprevir is filed under 4 classifications — including organic anion transporter 3 (oat3) substrates, organic anion transporter 1 (oat1) substrates, cytochrome p450 3a4 (cyp3a4) substrates. Arenaria Rubra has documented interactions with 1 drug class — the most serious being acetylcholinesterase (ache) inhibitors (moderate) — and none of Elbasvir, Grazoprevir’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Arenaria Rubra Does Interact With Other Medications

Arenaria Rubra has 17 moderate known drug interactions in our database — Elbasvir, Grazoprevir isn’t one of them. If you take anything else, check it against the full list below.

Moderate 17 No known interaction 2,813 (incl. Elbasvir, Grazoprevir)
Taking anything else?

Check Another of Your Medications Against Arenaria Rubra

Covers the 2,830 medications we’ve checked against Arenaria Rubra. Pick one to open its full report.

What to actually watch for

What Elbasvir, Grazoprevir’s Own FDA Label Lists

This is not an interaction — none of it involves Arenaria Rubra. These are the most notable effects listed in the ADVERSE REACTIONS section of Elbasvir, Grazoprevir’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 7 of them are worth acting on rather than waiting out — marked below.

  • Low mood Worth acting on
  • Kidney problems Worth acting on
  • Anemia Worth acting on
  • Shortness of breath Worth acting on
  • A severe allergic reaction Worth acting on
  • Liver problems Worth acting on
  • A higher chance of infection Worth acting on
  • Tiredness mentioned in 22.6% of FDA reports for Elbasvir, Grazoprevir
  • Mood changes or irritability
  • Trouble sleeping mentioned in 7.3% of FDA reports for Elbasvir, Grazoprevir

Showing the 10 most notable of 17 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Elbasvir, Grazoprevir. Read the label on DailyMed › Where a percentage is shown, it is the share of 4,243 voluntary FDA FAERS reports for Elbasvir, Grazoprevir that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Arenaria Rubra’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Arenaria Rubra side to compare — that is a limit of the record, not a statement that Arenaria Rubra has no side effects.

Everything else you take

See Every Supplement That Interacts With Elbasvir, Grazoprevir

This page covers Arenaria Rubra only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Elbasvir, Grazoprevir page lists 140 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 96 moderate · 41 minor.

From our pharmacist’s overview on the Elbasvir, Grazoprevir page

“Zepatier (elbasvir and grazoprevir) is a fixed-course hepatitis C cure, and success depends on holding steady drug levels through every week of treatment, so this list deserves genuine care. Three of the 140 ingredients on file rate major.”

Reviewed by 2 · Jul 18, 2026

Open the Elbasvir, Grazoprevir interaction page

How much people look this up

Where Arenaria Rubra and Elbasvir, Grazoprevir Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Arenaria Rubra
Top half

#636 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Elbasvir, Grazoprevir
Steady interest

#2,201 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Arenaria Rubra is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Arenaria Rubra reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Arenaria Rubra and Elbasvir, Grazoprevir records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Arenaria Rubra

What is Arenaria Rubra?

Arenaria Rubra
  • Urinary and bladder complaints
  • Kidney stones ("stone-breaking")
  • Mild diuretic
  • Traditional digestive support
  • Antioxidant interest

Arenaria rubra (Spergularia rubra) is a small herb used in folk medicine, mainly for urinary and kidney complaints. Modern evidence is very limited and comes mostly from laboratory studies, so its benefits in people are not proven. Talk with a pharmacist or doctor before using it, especially if you have a medical condition or are pregnant.

Spergularia rubra · Caryophyllaceae · Above-ground parts (aerial parts) · Tea (infusion), dried herb, liquid extracts

An interaction check asks whether these two react with each other — it does not ask whether Arenaria Rubra is a good idea for someone in your situation. Here is what our Arenaria Rubra record says about it on its own.

Arenaria Rubra: dosing

There is no established or standardized dose for Arenaria rubra. Reliable dosing studies in humans are lacking, so a safe and effective amount has not been defined.If you choose to use a commercial product, follow the directions on the label and do not exceed the recommended amount.

From our Arenaria Rubra monograph — the full record covers uses, side effects and every documented interaction.

Read the full Arenaria Rubra monograph & all interactions
Medication

About Elbasvir and Grazoprevir

What Is Elbasvir and Grazoprevir Used For?

Brand name: Zepatier

Zepatier treats chronic hepatitis C virus (HCV) genotype 1 or genotype 4 infection in adults and children 12 years of age and older (or weighing at least 30 kg). It works for people who have never been treated before as well as those who have tried certain other treatments.

Depending on the specific genotype and treatment history, Zepatier may be prescribed on its own or combined with another antiviral medicine called ribavirin. Your prescriber will determine the right combination and length of treatment for your situation.

See full Elbasvir and Grazoprevir drug information
Keep checking

Other Drugs & Arenaria Rubra

Browse every other medication we’ve checked against Arenaria Rubra — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
17Moderate
0Minor
2,812No known interaction
17 Moderate 2,812 No interaction
Moderate

17 interactions

No interaction 2,812 drugs checked — show the list

We also checked Arenaria Rubra against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,812 medications checked with no known interaction — see the full Arenaria Rubra list.

See the full Arenaria Rubra interactions page
See every supplement checked against Elbasvir, Grazoprevir, ranked by severity
Evidence & sources

Arenaria Rubra References

The 2 sources that drive our Arenaria Rubra monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Arenaria Rubra is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Using Dietary Supplements Wisely — NIH National Center for Complementary and Integrative Health Source
  2. Herbal Medicine — MedlinePlus (NIH) Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Arenaria Rubra and Elbasvir, Grazoprevir Together: Common Questions

Is it safe to take Arenaria Rubra with Elbasvir, Grazoprevir?
We do not list a known interaction between Arenaria Rubra and Elbasvir, Grazoprevir. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Arenaria Rubra and Elbasvir, Grazoprevir combination checked?
Interactions in our licensed database are recorded against drug classes. Elbasvir, Grazoprevir is filed under 4 classifications, and Arenaria Rubra has documented interactions with 1 drug class — none of Elbasvir, Grazoprevir's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Arenaria Rubra interact with any other medications?
Yes. Arenaria Rubra has 17 documented drug interactions in our database — Elbasvir, Grazoprevir is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Elbasvir, Grazoprevir interact with any supplements?
Yes. Elbasvir, Grazoprevir has documented interactions with 140 supplements in our database — Arenaria Rubra is not one of them. The Elbasvir, Grazoprevir interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Arenaria Rubra monograph Uses, safety profile, and every drug interaction in one place Elbasvir and Grazoprevir drug information The full plain-English guide to this medication Elbasvir, Grazoprevir supplement interactions Every supplement checked against Elbasvir, Grazoprevir, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Elbasvir, Grazoprevir and Arenaria Rubra?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.