Avens + Varenicline
Varenicline brand names: Chantix, Champix, Tyrvaya.
We found no known interaction between Avens and Varenicline in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Varenicline states a food rule worth keeping to.
Avens and Varenicline
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Varenicline and Avens in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Avens at all — not against Varenicline, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Avens safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Avens in Pregnancy & Breastfeeding
When used orally because avens seems to have an effect on the menstrual cycle; avoid using.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
Some Varenicline Products Have a Food Rule — Avens Should Not Break It
At least one FDA label for a product containing Varenicline says to take it with food. If you take Avens on an empty stomach out of habit, keep them separate — and take Varenicline with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Varenicline products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
Varenicline tablets should be taken orally after eating and with a full glass of water.
From the Dosage and Administration section of the FDA label we read for Varenicline — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
See Every Supplement That Interacts With Varenicline
This page covers Avens only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Varenicline page lists 20 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Beer (moderate), Coffee Charcoal (moderate), European Mandrake (moderate) and Glucomannan (moderate).
By severity: 1 major · 10 moderate · 9 minor.
From our pharmacist’s overview on the Varenicline page
“For anyone taking varenicline (Chantix, Champix, Tyrvaya) to quit smoking, this list earns real caution rather than a quick skim. Activated charcoal is the single entry rated major; it binds many medicines in the gut and can pull varenicline's blood levels down, and losing that support mid-quit is a genuine setback.”
Reviewed by 2 · Jul 18, 2026
Taking Avens as Part of a Dietary Supplement Product? Check It for Interactions
We hold 8 real supplement products containing Avens, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Avens. Even though Avens itself has no known interaction with Varenicline, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Avens and Varenicline Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#696 of 1,452 supplements looked up here in the last 7 days
#674 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Avens reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Avens and Varenicline records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Avens
What is Avens?
- Diarrhea
- Indigestion and dyspepsia
- Gas (flatulence)
- Sore throat and mouth rinses
- Mild inflammation
Avens is a traditional European herb whose root and leaves are rich in tannins and have long been used as a tea for diarrhea and digestive upset. Solid human research is lacking, so its benefits are unproven. If you choose to try it, use it short-term, follow the product label, and check first with your pharmacist or doctor.
Geum urbanum · Rosaceae · Dried aerial (flowering) parts and roots · Tea (infusion), decoction, dried herb, root powder, tincture
An interaction check asks whether these two react with each other — it does not ask whether Avens is a good idea for someone in your situation. Here is what our Avens record says about it on its own.
Avens: dosing
There is no officially established or standardized dose for Avens. Traditional sources describe steeping a small amount of dried herb in hot water as a tea, or briefly boiling the dried root to make a decoction.Because product strengths vary widely, the safest approach is to follow the directions on the product label and not exceed them.
From our Avens monograph — the full record covers uses, side effects and every documented interaction.
About Varenicline
What Is Varenicline Used For?
Brand names: Chantix, Champix, Tyrvaya
Varenicline tablets — sold under brand names including Chantix — are used to help adults quit smoking. They work as part of a structured smoking cessation program.
Tyrvaya (varenicline solution) nasal spray is a separate product used to treat the signs and symptoms of dry eye disease. It is not used for smoking cessation.
Most-Reported Side Effects for Varenicline
From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Avens
Browse every other medication we’ve checked against Avens — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Avens against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Ivermectin ›
- Testosterone ›
- Losartan Potassium ›
- Abemaciclib ›
- Aspirin ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Escitalopram ›
- Rivaroxaban ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Methamphetamine ›
- Tirzepatide ›
- Tadalafil ›
- Ibuprofen ›
- Valacyclovir ›
- Warfarin Sodium ›
- Hydroxyurea ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Amitriptyline ›
- Propranolol ›
- Lisdexamfetamine ›
- Metformin ›
- Amoxicillin ›
- Isotretinoin ›
- Lisinopril ›
- Methotrexate ›
- Amlodipine Besylate ›
- Bendamustine ›
- Amphetamine ›
- Bupropion ›
- Doxycycline ›
- Fluoxetine ›
- Azithromycin ›
- Acyclovir ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Levothyroxine, Liothyronine ›
- Acetaminophen, Codeine ›
- Naproxen ›
- Quetiapine ›
- Clonazepam ›
- Omeprazole ›
- Duloxetine ›
- Letrozole ›
- Methylene Blue ›
- Citalopram ›
- Buspirone ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Avens list.
Avens References
The 1 references that drive our Avens monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Avens and Varenicline Together: Common Questions
Is it safe to take Avens with Varenicline?
Should I take Avens and Varenicline at the same time of day?
Does Varenicline interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.