Herb & supplement monograph

Avens Drug Interactions, Uses, Safety & More

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Interaction report

Drugs that interact with Avens

0 medications have a known interaction with Avens, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Avens. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Avens combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Avens: Uses, Safety & Side Effects

The bottom line

Avens is a traditional European herb whose root and leaves are rich in tannins and have long been used as a tea for diarrhea and digestive upset. Solid human research is lacking, so its benefits are unproven. If you choose to try it, use it short-term, follow the product label, and check first with your pharmacist or doctor.

Avens
Scientific name
Geum urbanum
Family
Rosaceae
Part used
Dried aerial (flowering) parts and roots
Common forms
Tea (infusion), decoction, dried herb, root powder, tincture
People commonly use it for
  • Diarrhea
  • Indigestion and dyspepsia
  • Gas (flatulence)
  • Sore throat and mouth rinses
  • Mild inflammation

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Generally used in food-like amounts, but human safety data are very limited.

PregnancyPossibly Unsafe

When used orally because avens seems to have an effect on the menstrual cycle; avoid using.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Avens (Geum urbanum) is a small perennial plant in the rose family. It grows wild in woodlands and shady spots across Europe, parts of Asia, and has spread to other regions. It is also known by names like Benedict's Herb, Bennet's Root, Colewort, and Blessed Herb.

Both the leafy flowering parts and the roots have been used in traditional European herbal medicine. The root has a faintly clove-like smell because it contains a compound called eugenol. People most often prepare Avens as a tea or a stronger boiled root preparation.

Historically, it was used for stomach and bowel complaints, as a gargle for sore throats, and as a general tonic. Today it is a fairly uncommon herb and is not a mainstream supplement.

Uses & effectiveness

Avens has a long history of traditional use, but high-quality human studies are essentially lacking. This means we cannot say it is proven to work for any condition.

People have used Avens for:

  • Diarrhea — its tannins are astringent and may help firm up loose stools, but this is based on tradition and lab reasoning, not strong clinical trials.
  • Indigestion, gas, and stomach upset — used traditionally as a digestive tea.
  • Sore throat and mouth irritation — used as a gargle or rinse.
  • Mild inflammation — some laboratory studies suggest certain root compounds have anti-inflammatory activity, but this has not been confirmed in people.

Overall, the evidence is weak and mostly preliminary. Most claims come from tradition, lab (test-tube) experiments, or animal research rather than well-designed human trials.

How it works

Avens contains tannins (including ellagitannins), ellagic acid derivatives, procyanidins, resins, a volatile oil, and eugenol. Tannins are astringent, meaning they bind to proteins and can tighten tissues. This astringent action is the usual explanation for why a tannin-rich tea might ease diarrhea or soothe an irritated throat.

Laboratory studies have looked at compounds from Avens root, such as gemin A, and found possible anti-inflammatory and antioxidant effects in cell-based experiments. Eugenol is known to have mild antimicrobial and numbing-type properties.

It is important to know that these mechanisms come mostly from test-tube and animal research. Showing an effect in a lab does not prove the herb will help when a person drinks it as a tea.

Safety & precautions

Avens has been used as a food-like herbal tea for a long time, and short-term use of normal amounts is generally thought to be reasonably well tolerated. However, modern safety studies in humans are very limited, so we cannot call it clearly safe.

Because it is high in tannins, large amounts or long-term use could irritate the stomach and may interfere with how your body absorbs certain nutrients like iron. People with ulcers or sensitive stomachs should be cautious.

Pregnancy: There is not enough reliable information, so pregnant women should avoid Avens. Breastfeeding: Safety is unknown, so it is best to avoid it while nursing. Children, and people with liver or kidney problems, should not use it without medical advice.

If you have a known allergy to plants in the rose family, be cautious. Always talk with your pharmacist or doctor before starting any herbal product.

Side effects

Reported side effects are not well documented because formal studies are scarce. Based on its tannin content, possible effects include stomach upset, nausea, or constipation, especially with strong preparations or frequent use.

Allergic reactions are possible, particularly in people sensitive to other rose-family plants. Stop using it and seek medical care if you notice rash, itching, swelling, or trouble breathing.

Because human data are so limited, treat any unexpected symptom seriously and stop the herb if you feel unwell.

Dosing

There is no officially established or standardized dose for Avens. Traditional sources describe steeping a small amount of dried herb in hot water as a tea, or briefly boiling the dried root to make a decoction.

Because product strengths vary widely, the safest approach is to follow the directions on the product label and not exceed them. Use it short-term rather than daily for long periods.

Always check with a pharmacist or doctor before using Avens, especially if you take medicines, are older, or have a health condition.

Pregnancy & Breastfeeding

Avens & Pregnancy

Possibly Unsafe

When used orally because avens seems to have an effect on the menstrual cycle; avoid using.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

Avens & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 1 references that drive our Avens monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Brand directory

Brands that make products with Avens

2 brands in our database make a supplement containing Avens.

Pharmacist Counseling Corner

Avens: Common Questions

Does Avens interact with prescription medications?
We do not currently list any known drug interactions for Avens. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Avens interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Avens with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Avens interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Avens used for?
It is a traditional European herb used mainly as a tea for diarrhea, indigestion, gas, and sore throats. These uses come from tradition, and strong scientific proof is lacking.
Is Avens safe to take?
Short-term use of normal tea amounts is generally thought to be reasonably well tolerated, but human safety data are very limited. Because it is high in tannins, avoid large or long-term doses and check with your pharmacist first.
Can I use Avens during pregnancy or breastfeeding?
No. There isn't enough reliable safety information, so it's best to avoid Avens if you are pregnant or breastfeeding.
How is Avens usually taken?
It is most often taken as a tea made from the dried leaves and flowers, or as a stronger decoction made by boiling the root. Follow the product label, since there is no standardized dose.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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