Avens Drug Interactions, Uses, Safety & More
What is this page for?
First and foremost: how Avens interacts with medications. The heart of this page is the interaction list — every drug Avens is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Avens is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Avens against your medication
Add one medicationDrugs that interact with Avens
0 medications have a known interaction with Avens, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Avens. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Avens combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Avens: Uses, Safety & Side Effects
Avens is a traditional European herb whose root and leaves are rich in tannins and have long been used as a tea for diarrhea and digestive upset. Solid human research is lacking, so its benefits are unproven. If you choose to try it, use it short-term, follow the product label, and check first with your pharmacist or doctor.

- Scientific name
- Geum urbanum
- Family
- Rosaceae
- Part used
- Dried aerial (flowering) parts and roots
- Common forms
- Tea (infusion), decoction, dried herb, root powder, tincture
- Diarrhea
- Indigestion and dyspepsia
- Gas (flatulence)
- Sore throat and mouth rinses
- Mild inflammation
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
Generally used in food-like amounts, but human safety data are very limited.
When used orally because avens seems to have an effect on the menstrual cycle; avoid using.
Read the full pregnancy detailInsufficient reliable information available; avoid using.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Avens (Geum urbanum) is a small perennial plant in the rose family. It grows wild in woodlands and shady spots across Europe, parts of Asia, and has spread to other regions. It is also known by names like Benedict's Herb, Bennet's Root, Colewort, and Blessed Herb.
Both the leafy flowering parts and the roots have been used in traditional European herbal medicine. The root has a faintly clove-like smell because it contains a compound called eugenol. People most often prepare Avens as a tea or a stronger boiled root preparation.
Historically, it was used for stomach and bowel complaints, as a gargle for sore throats, and as a general tonic. Today it is a fairly uncommon herb and is not a mainstream supplement.
Uses & effectiveness
Avens has a long history of traditional use, but high-quality human studies are essentially lacking. This means we cannot say it is proven to work for any condition.
People have used Avens for:
- Diarrhea — its tannins are astringent and may help firm up loose stools, but this is based on tradition and lab reasoning, not strong clinical trials.
- Indigestion, gas, and stomach upset — used traditionally as a digestive tea.
- Sore throat and mouth irritation — used as a gargle or rinse.
- Mild inflammation — some laboratory studies suggest certain root compounds have anti-inflammatory activity, but this has not been confirmed in people.
Overall, the evidence is weak and mostly preliminary. Most claims come from tradition, lab (test-tube) experiments, or animal research rather than well-designed human trials.
How it works
Avens contains tannins (including ellagitannins), ellagic acid derivatives, procyanidins, resins, a volatile oil, and eugenol. Tannins are astringent, meaning they bind to proteins and can tighten tissues. This astringent action is the usual explanation for why a tannin-rich tea might ease diarrhea or soothe an irritated throat.
Laboratory studies have looked at compounds from Avens root, such as gemin A, and found possible anti-inflammatory and antioxidant effects in cell-based experiments. Eugenol is known to have mild antimicrobial and numbing-type properties.
It is important to know that these mechanisms come mostly from test-tube and animal research. Showing an effect in a lab does not prove the herb will help when a person drinks it as a tea.
Safety & precautions
Avens has been used as a food-like herbal tea for a long time, and short-term use of normal amounts is generally thought to be reasonably well tolerated. However, modern safety studies in humans are very limited, so we cannot call it clearly safe.
Because it is high in tannins, large amounts or long-term use could irritate the stomach and may interfere with how your body absorbs certain nutrients like iron. People with ulcers or sensitive stomachs should be cautious.
Pregnancy: There is not enough reliable information, so pregnant women should avoid Avens. Breastfeeding: Safety is unknown, so it is best to avoid it while nursing. Children, and people with liver or kidney problems, should not use it without medical advice.
If you have a known allergy to plants in the rose family, be cautious. Always talk with your pharmacist or doctor before starting any herbal product.
Side effects
Reported side effects are not well documented because formal studies are scarce. Based on its tannin content, possible effects include stomach upset, nausea, or constipation, especially with strong preparations or frequent use.
Allergic reactions are possible, particularly in people sensitive to other rose-family plants. Stop using it and seek medical care if you notice rash, itching, swelling, or trouble breathing.
Because human data are so limited, treat any unexpected symptom seriously and stop the herb if you feel unwell.
Dosing
There is no officially established or standardized dose for Avens. Traditional sources describe steeping a small amount of dried herb in hot water as a tea, or briefly boiling the dried root to make a decoction.
Because product strengths vary widely, the safest approach is to follow the directions on the product label and not exceed them. Use it short-term rather than daily for long periods.
Always check with a pharmacist or doctor before using Avens, especially if you take medicines, are older, or have a health condition.
Avens & Pregnancy
Avens & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 1 references that drive our Avens monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Brands that make products with Avens
2 brands in our database make a supplement containing Avens.
Supplement products with Avens
8 products in our database contain Avens. Open any to see its full ingredient list and every drug interaction we check.
Avens: Common Questions
Does Avens interact with prescription medications?
How are Avens interactions rated?
Is it safe to take Avens with my medications?
Where does this Avens interaction information come from?
What is Avens used for?
Is Avens safe to take?
Can I use Avens during pregnancy or breastfeeding?
How is Avens usually taken?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Products that contain Avens
A rotating sample of real supplements in our database that list Avens — open any to see its full ingredients and every drug interaction we check.
- Benedict's Herb Mint Flavor by TerraVita
- Benedict's Herb Vanilla Flavor by TerraVita
- Benedict's Herb Strawberry Flavor by TerraVita
- Benedict's Herb Powder by TerraVita Premium Collection
- Benedict's Herb Chocolate Flavor by TerraVita
- Benedict's Herb by TerraVita
- Benedict's Herb 450 mg by TerraVita Premium Collection
- Benedict's Herb Powder by TerraVita Premium Collection
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