Drug & supplement interaction

Bulbous Buttercup + Tinzaparin

Tinzaparin brand name: Innohep.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Bulbous Buttercup and Tinzaparin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Bulbous Buttercup and Tinzaparin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tinzaparin and Bulbous Buttercup in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Bulbous Buttercup at all — not against Tinzaparin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Bulbous Buttercup safety at a glance

Bulbous Buttercup overall Avoid The fresh plant is toxic and irritating; only highly diluted homeopathic forms are used, and these are unproven.
Pregnancy Likely Unsafe When used orally or topically; avoid using. Read the full pregnancy detail
Breastfeeding Likely Unsafe When used orally or topically; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tinzaparin and Bulbous Buttercup? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Bulbous Buttercup Itself Has Been Linked To

This is not an interaction — nothing below involves Tinzaparin. It is the side-effect record for Bulbous Buttercup on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Bulbous Buttercup, this list is the first place to look.

  • Diarrhea Additional detail

    “Orally, ingestion of bulbous buttercup can cause severe irritation of the urinary and gastrointestinal tracts, with colic and diarrhea (18).

    Topically, skin contact can cause blisters and burns that are difficult to heal (18).”

    Bulbous Buttercup · Natural Medicines adverse-effect record, reported in burns.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    “Orally, ingestion of bulbous buttercup may cause severe irritation of the gastrointestinal tract, with colic and diarrhea (18).”

    Bulbous Buttercup · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Everything above comes from the Natural Medicines adverse-effect record for Bulbous Buttercup — expand a row for the licensed statement it rests on. We haven’t matched Tinzaparin to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Tinzaparin.

Special populations

Bulbous Buttercup in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Unsafe

When used orally or topically; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Tinzaparin

This page covers Bulbous Buttercup only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tinzaparin page lists 218 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Danshen (major), Piracetam (major), Aconite (moderate) and Allspice (moderate).

By severity: 3 major · 190 moderate · 25 minor.

From our pharmacist’s overview on the Tinzaparin page

“Someone giving themselves tinzaparin (Innohep) injections is usually recovering from a blood clot in the leg or lung, or trying to prevent one, and that is exactly why this list of 218 supplements deserves real seriousness rather than a shrug. Nearly all of them, 202 in fact, push in one direction: extra bleeding risk on top of a drug…”

Reviewed by 2 · Jul 18, 2026

Open the Tinzaparin interaction page

One more smart check

Taking Bulbous Buttercup as Part of a Dietary Supplement Product? Check It for Interactions

We hold 4 real supplement products containing Bulbous Buttercup, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Bulbous Buttercup. Even though Bulbous Buttercup itself has no known interaction with Tinzaparin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Bulbous Buttercup and Tinzaparin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Bulbous Buttercup
Steady interest

#1,320 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tinzaparin
Top 25%

#352 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Bulbous Buttercup reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Bulbous Buttercup and Tinzaparin records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Bulbous Buttercup

What is Bulbous Buttercup?

  • Nerve pain and shingles-related discomfort (homeopathic use)
  • Muscle and chest wall pain
  • Skin blistering and eruptions (traditional)
  • Rheumatic aches (folk use)

Bulbous buttercup is a wild flowering plant that is toxic and irritating when fresh, and it is used today mainly in heavily diluted homeopathic remedies. There is no solid scientific evidence that it treats any medical condition, and the raw plant can cause serious skin and digestive harm, so it should not be eaten or applied directly.

Ranunculus bulbosus · Ranunculaceae · Whole fresh plant, leaves, and flowers (mainly used in homeopathic preparations) · Homeopathic dilutions (pellets, liquid), rarely topical folk preparations

An interaction check asks whether these two react with each other — it does not ask whether Bulbous Buttercup is a good idea for someone in your situation. Here is what our Bulbous Buttercup record says about it on its own.

Bulbous Buttercup: dosing

There is no established safe or effective dose of bulbous buttercup for any health condition. The raw plant should not be taken at all.If a homeopathic product is used, follow the directions on the label, since potencies and dosing vary widely between products.

From our Bulbous Buttercup monograph — the full record covers uses, side effects and every documented interaction.

Read the full Bulbous Buttercup monograph & all interactions
Keep checking

Other Drugs & Bulbous Buttercup

Browse every other medication we’ve checked against Bulbous Buttercup — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Bulbous Buttercup References

The 1 references that drive our Bulbous Buttercup monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Bulbous Buttercup and Tinzaparin Together: Common Questions

Is it safe to take Bulbous Buttercup with Tinzaparin?
We do not list a known interaction between Bulbous Buttercup and Tinzaparin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Tinzaparin interact with any supplements?
Yes. Tinzaparin has documented interactions with 218 supplements in our database — Bulbous Buttercup is not one of them. The Tinzaparin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Tinzaparin and Bulbous Buttercup?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.