Drug & supplement interaction

Butylated Hydroxytoluene (bht) + Tinidazole

Tinidazole brand name: Tindamax.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Butylated Hydroxytoluene (bht) and Tinidazole in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Tinidazole states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

Know someone taking this? Share
Interaction report

Butylated Hydroxytoluene (bht) and Tinidazole

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tinidazole and Butylated Hydroxytoluene (bht) in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Butylated Hydroxytoluene (bht) at all — not against Tinidazole, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Butylated Hydroxytoluene (bht) safety at a glance

Butylated Hydroxyt... overall Use caution Approved as a food preservative in small amounts, but using concentrated BHT as a supplement is not well studied and may be harmful.
Pregnancy Likely Safe When used orally as a food additive. Read the full pregnancy detail
Breastfeeding Likely Safe When used orally as a food additive. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tinidazole and Butylated Hydroxytoluene (bht)? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Butylated Hydroxytoluene (bht) and Tinidazole May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Confusion Worth acting on Additional detail

    Butylated Hydroxytoluene (bht)

    “Orally, BHT can cause severe gastritis characterized by severe epigastric pain, nausea, and vomiting. Symptoms may progress to weakness, dizziness, confusion, slurred speech, unsteady gait, and loss of consciousness. BHT is highly lipid soluble. It may cross the blood brain barrier, causing psychotropic symptoms. BHT has been associated with development of cancer;”

    Butylated Hydroxytoluene (bht) · Natural Medicines adverse-effect record, reported in cancer.

    5 sources cited
    1. 10303. Shlian DM, Goldstone J. Toxicity of butylated hydroxytoluene. N Engl J Med 1986;314:648-9. DOI
    2. 10698. Grogan MW. Toxicity from BHT ingestion. West J Med 1986;145:245-6.
    3. 10699. Shlian DM, Goldstone J. More on BHT toxicity. West J Med 1986;145:699.
    4. 10292. Williams GM, Iatropoulos MJ, Whysner J. Safety assessment of butylated hydroxyanisole and butylated hydroxytoluene as antioxidant food additives. Food Chem Toxicol 1999;37:1027-38.. PubMed
    5. 10293. Botterweck AA, Verhagen H, Goldbohm RA, et al. Intake of butylated hydroxyanisole and butylated hydroxytoluene and stomach cancer risk: results from analyses in the Netherlands Cohort Study. Food Chem Toxicol 2000;38:599-605.. PubMed

    Tinidazole

    Listed in the ADVERSE REACTIONS section of the FDA label for Tinidazole. Read the label on DailyMed ›

  • Stomach upset / Dizziness / Vomiting / Nausea Additional detail

    Butylated Hydroxytoluene (bht)

    Recorded for Butylated Hydroxytoluene (bht) in the same Natural Medicines adverse-effect record shown under Confusion above.

    Tinidazole

    Listed in the ADVERSE REACTIONS section of the FDA label for Tinidazole. Read the label on DailyMed ›

Reported for Butylated Hydroxytoluene (bht) but not commonly for Tinidazole: fainting.

Effects for Tinidazole come from the ADVERSE REACTIONS section of its FDA label; effects for Butylated Hydroxytoluene (bht) come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Butylated Hydroxytoluene (bht) in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When used orally as a food additive.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Tinidazole Products Have a Food Rule — Butylated Hydroxytoluene (bht) Should Not Break It

At least one FDA label for a product containing Tinidazole says to take it with food. If you take Butylated Hydroxytoluene (bht) on an empty stomach out of habit, keep them separate — and take Tinidazole with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Tinidazole products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

2 DOSAGE AND ADMINISTRATION 2 DOSAGE AND ADMINISTRATION Trichomoniasis: a single 2 g oral dose taken with food.

From the Dosage and Administration section of the FDA label we read for Tinidazole — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Tinidazole

This page covers Butylated Hydroxytoluene (bht) only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tinidazole page lists 140 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 96 moderate · 41 minor.

From our pharmacist’s overview on the Tinidazole page

“Tinidazole (Tindamax) is a short antibiotic course, often for parasitic or vaginal infections, and its supplement list is one I would genuinely slow down for. Each of the three major-rated pairings can wreck treatment in its own way: St.”

Reviewed by 2 · Jul 18, 2026

Open the Tinidazole interaction page

How much people look this up

Where Butylated Hydroxytoluene (bht) and Tinidazole Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Butylated Hydroxytoluene (bht)
Steady interest

#1,318 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tinidazole
Steady interest

#1,428 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Butylated Hydroxytoluene (bht) reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Butylated Hydroxytoluene (bht) and Tinidazole records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Butylated Hydroxytoluene (bht)

What is Butylated Hydroxytoluene (bht)?

  • Antioxidant supplement
  • Antiviral (popular self-treatment for herpes-type viruses)
  • Food and supplement preservative
  • General 'anti-aging' use

Butylated hydroxytoluene (BHT) is a man-made antioxidant used mainly as a preservative in foods, cosmetics, and supplements. Some people take it as a supplement hoping for antiviral or anti-aging effects, but human evidence for these uses is very weak, and taking concentrated BHT carries real safety concerns. Talk with a pharmacist or doctor before using it as a supplement.

Synthetic compound (not from a plant) · Capsules, tablets, liquid drops, powder

An interaction check asks whether these two react with each other — it does not ask whether Butylated Hydroxytoluene (bht) is a good idea for someone in your situation. Here is what our Butylated Hydroxytoluene (bht) record says about it on its own.

Butylated Hydroxytoluene (bht): dosing

There is no established or proven safe supplement dose of BHT. It is not a standardized medical treatment, and doses found in supplements vary widely.If you choose to use a BHT product, follow the directions on the label and do not exceed them.

From our Butylated Hydroxytoluene (bht) monograph — the full record covers uses, side effects and every documented interaction.

Read the full Butylated Hydroxytoluene (bht) monograph & all interactions
Medication

About Tinidazole

What Is Tinidazole Used For?

Brand name: Tindamax

Tinidazole tablets treat four types of infections: trichomoniasis (a sexually transmitted infection), giardiasis (a parasitic gut infection), amebiasis (including intestinal infection and amebic liver abscess), and bacterial vaginosis (a vaginal bacterial imbalance). Treatment of giardiasis and amebiasis is approved for adults and children older than three years of age. Bacterial vaginosis is an approved use in adult women.

Because trichomoniasis is sexually transmitted, sexual partners must be treated at the same time to prevent re-infection. Tinidazole should only be used for confirmed or strongly suspected bacterial or parasitic infections — using it unnecessarily can contribute to antibiotic resistance.

See full Tinidazole drug information
Keep checking

Other Drugs & Butylated Hydroxytoluene (bht)

Browse every other medication we’ve checked against Butylated Hydroxytoluene (bht) — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Butylated Hydroxytoluene (bht) References

The 6 references that drive our Butylated Hydroxytoluene (bht) monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Williams GM, Iatropoulos MJ, Whysner J. Safety assessment of butylated hydroxyanisole and butylated hydroxytoluene as antioxidant food additives. Food Chem Toxicol 1999;37:1027-38.. PubMed
  2. Botterweck AA, Verhagen H, Goldbohm RA, et al. Intake of butylated hydroxyanisole and butylated hydroxytoluene and stomach cancer risk: results from analyses in the Netherlands Cohort Study. Food Chem Toxicol 2000;38:599-605.. PubMed
  3. Freeman DJ, Wenerstrom G, Spruance SL. Treatment of recurrent herpes simplex labialis with topical butylated hydroxytoluene. Clin Pharmacol Ther 1985;38:56-9.. PubMed
  4. Shlian DM, Goldstone J. Toxicity of butylated hydroxytoluene. N Engl J Med 1986;314:648-9. DOI
  5. Grogan MW. Toxicity from BHT ingestion. West J Med 1986;145:245-6.
  6. Shlian DM, Goldstone J. More on BHT toxicity. West J Med 1986;145:699.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Butylated Hydroxytoluene (bht) and Tinidazole Together: Common Questions

Is it safe to take Butylated Hydroxytoluene (bht) with Tinidazole?
We do not list a known interaction between Butylated Hydroxytoluene (bht) and Tinidazole. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Butylated Hydroxytoluene (bht) and Tinidazole have any of the same side effects?
Yes — our sources link each of them separately to 5 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Should I take Butylated Hydroxytoluene (bht) and Tinidazole at the same time of day?
At least one FDA label for a product containing Tinidazole says to take it with food. If you take Butylated Hydroxytoluene (bht) on an empty stomach out of habit, keep them separate and take Tinidazole with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Tinidazole products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Tinidazole interact with any supplements?
Yes. Tinidazole has documented interactions with 140 supplements in our database — Butylated Hydroxytoluene (bht) is not one of them. The Tinidazole interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Tinidazole and Butylated Hydroxytoluene (bht)?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.