Drug & supplement interaction

Canada Balsam + Cabotegravir Sodium

Cabotegravir Sodium brand name: Vocabria.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Canada Balsam and Cabotegravir Sodium in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Canada Balsam and Cabotegravir Sodium

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Cabotegravir Sodium and Canada Balsam in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Canada Balsam at all — not against Cabotegravir Sodium, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Canada Balsam safety at a glance

Canada Balsam overall Use caution Mainly used topically; resins and their oils can irritate skin and there is limited safety data for internal use.
Pregnancy Avoid Not enough safety information is available, so it is best avoided during pregnancy.
Breastfeeding Avoid There is no reliable safety data, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Cabotegravir Sodium and Canada Balsam? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Cabotegravir Sodium’s Own FDA Label Lists

This is not an interaction — none of it involves Canada Balsam. These are the most notable effects listed in the ADVERSE REACTIONS section of Cabotegravir Sodium’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 3 of them are worth acting on rather than waiting out — marked below.

  • Liver problems Worth acting on mentioned in 4.0% of FDA reports for Cabotegravir Sodium
  • A higher chance of infection Worth acting on
  • An allergic reaction Worth acting on
  • Bloating or gas
  • Back pain
  • Drowsiness
  • Reduced appetite
  • Muscle pain
  • Fever
  • Tiredness mentioned in 3.6% of FDA reports for Cabotegravir Sodium

Showing the 10 most notable of 17 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Cabotegravir Sodium. Read the label on DailyMed › Where a percentage is shown, it is the share of 1,558 voluntary FDA FAERS reports for Cabotegravir Sodium that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Canada Balsam’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Canada Balsam side to compare — that is a limit of the record, not a statement that Canada Balsam has no side effects.

Everything else you take

See Every Supplement That Interacts With Cabotegravir Sodium

This page covers Canada Balsam only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Cabotegravir Sodium page lists 29 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Breadfruit (moderate), Brussels Sprout (moderate), Cabbage (moderate) and Calcium D-glucarate (moderate).

By severity: 1 major · 18 moderate · 10 minor.

From our pharmacist’s overview on the Cabotegravir Sodium page

“Cabotegravir (Vocabria) is an HIV medicine, and keeping its blood level steady is what keeps the virus suppressed, so I read this list of 29 interacting supplements with genuine concern. The one major entry is activated charcoal, a popular detox remedy that soaks up drugs in the gut and cuts how much reaches you.”

Reviewed by 2 · Jul 18, 2026

Open the Cabotegravir Sodium interaction page

How much people look this up

Where Canada Balsam and Cabotegravir Sodium Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Canada Balsam
Steady interest

#1,333 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Cabotegravir Sodium
Top 25%

#349 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources.
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Canada Balsam and Cabotegravir Sodium records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Canada Balsam

What is Canada Balsam?

  • Topical wound and skin care
  • Soothing coughs and colds (traditional)
  • Antiseptic and antimicrobial uses
  • Aromatherapy and fragrance
  • Minor aches and irritations

Canada Balsam is the sticky oleoresin from the balsam fir tree, traditionally used on the skin and in folk cold remedies, and also widely used as a fragrance and a clear cement in microscopy and optics. There is very little high-quality human research supporting any health benefit, so it should be viewed as a traditional remedy rather than a proven treatment. Use it cautiously, mainly externally, and check with a pharmacist or doctor before using it medicinally.

Abies balsamea · Pinaceae · Oleoresin (resin) collected from the trunk; sometimes needles and bark · Resin (raw oleoresin), essential oil, salves and ointments, and as an ingredient in some traditional preparations

An interaction check asks whether these two react with each other — it does not ask whether Canada Balsam is a good idea for someone in your situation. Here is what our Canada Balsam record says about it on its own.

Canada Balsam: dosing

There is no established or standardized medicinal dose for Canada Balsam. It has not been studied enough in people to know a safe and effective amount.If you use a commercial product, such as a salve or an essential oil blend, follow the directions on the label.

From our Canada Balsam monograph — the full record covers uses, side effects and every documented interaction.

Read the full Canada Balsam monograph & all interactions
Medication

About Cabotegravir

What Is Cabotegravir Used For?

Brand name: Vocabria

Vocabria (cabotegravir) tablets are used in combination with rilpivirine (Edurant) to treat HIV-1 infection in adults and adolescents aged 12 and older who weigh at least 35 kg and whose HIV is already virologically suppressed (virus levels undetectable or very low on their current regimen). Vocabria tablets serve as a short-term oral lead-in — taken for roughly one month — before switching to long-acting injectable therapy.

Cabotegravir tablets are also used as an oral lead-in for HIV-1 pre-exposure prophylaxis (PrEP) — helping HIV-negative adults and adolescents (weighing at least 35 kg) confirm they tolerate the drug before starting injectable PrEP. Both uses require confirmed HIV-negative status before starting.

Most-Reported Side Effects for Cabotegravir Sodium

From FAERS, the FDA’s public side-effect reporting system (1,558 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Viral load increased 109 reports
Injection site pain 105 reports
Virologic failure 64 reports
Hepatitis b 63 reports
Pathogen resistance 61 reports
See full Cabotegravir drug information
Keep checking

Other Drugs & Canada Balsam

Browse every other medication we’ve checked against Canada Balsam — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Sources

Sources & How We Checked

We checked Canada Balsam against Cabotegravir Sodium in the Natural Medicines interaction database and found no documented interaction on file. The medication overview comes from MedlinePlus, and supplement label details from the NIH Dietary Supplement Label Database.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Canada Balsam and Cabotegravir Sodium Together: Common Questions

Is it safe to take Canada Balsam with Cabotegravir Sodium?
We do not list a known interaction between Canada Balsam and Cabotegravir Sodium. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Cabotegravir Sodium interact with any supplements?
Yes. Cabotegravir Sodium has documented interactions with 29 supplements in our database — Canada Balsam is not one of them. The Cabotegravir Sodium interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Cabotegravir Sodium and Canada Balsam?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.