Canada Balsam + Hydroxychloroquine
Hydroxychloroquine brand name: Plaquenil.
We found no known interaction between Canada Balsam and Hydroxychloroquine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Hydroxychloroquine states a food rule worth keeping to.
Canada Balsam and Hydroxychloroquine
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Hydroxychloroquine and Canada Balsam in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Canada Balsam at all — not against Hydroxychloroquine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Canada Balsam safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Some Hydroxychloroquine Products Have a Food Rule — Canada Balsam Should Not Break It
At least one FDA label for a product containing Hydroxychloroquine says to take it with food. If you take Canada Balsam on an empty stomach out of habit, keep them separate — and take Hydroxychloroquine with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Hydroxychloroquine products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
Rheumatoid Arthritis in Adults ( 2.3 ): Initial dosage: 400 mg to 600 mg daily Chronic dosage: 200 mg once daily or 400 mg once daily (or in two divided doses) Systemic Lupus Erythematosus in Adults ( 2.4 ): 200 mg once daily or 400 mg once daily (or in two divided doses) Chronic Discoid Lupus Erythematosus in Adults ( 2.5 ): 200 mg once daily or 400 mg once daily (or in two divided doses) 2.1 Imp
From the Dosage and Administration section of the FDA label we read for Hydroxychloroquine — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
Questions About Canada Balsam or Hydroxychloroquine
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Canada Balsam or Hydroxychloroquine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Hydroxychloroquine
This page covers Canada Balsam only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Hydroxychloroquine page lists 32 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).
By severity: 7 major · 16 moderate · 9 minor.
From our pharmacist’s overview on the Hydroxychloroquine page
“Hydroxychloroquine (Plaquenil) can stretch the QT interval on its own, the pause between heartbeats that, prolonged too far, can trigger a dangerous rhythm. Thirteen of the supplements and herbs on this page add to that same effect, grapefruit in large amounts among them, and that overlap is why this list calls for genuine care rather…”
Reviewed by 2 · Jul 18, 2026
Where Canada Balsam and Hydroxychloroquine Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,365 of 1,452 supplements looked up here in the last 7 days
#694 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources.
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Canada Balsam and Hydroxychloroquine records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Canada Balsam
What is Canada Balsam?
- Topical wound and skin care
- Soothing coughs and colds (traditional)
- Antiseptic and antimicrobial uses
- Aromatherapy and fragrance
- Minor aches and irritations
Canada Balsam is the sticky oleoresin from the balsam fir tree, traditionally used on the skin and in folk cold remedies, and also widely used as a fragrance and a clear cement in microscopy and optics. There is very little high-quality human research supporting any health benefit, so it should be viewed as a traditional remedy rather than a proven treatment. Use it cautiously, mainly externally, and check with a pharmacist or doctor before using it medicinally.
Abies balsamea · Pinaceae · Oleoresin (resin) collected from the trunk; sometimes needles and bark · Resin (raw oleoresin), essential oil, salves and ointments, and as an ingredient in some traditional preparations
An interaction check asks whether these two react with each other — it does not ask whether Canada Balsam is a good idea for someone in your situation. Here is what our Canada Balsam record says about it on its own.
Canada Balsam: dosing
There is no established or standardized medicinal dose for Canada Balsam. It has not been studied enough in people to know a safe and effective amount.If you use a commercial product, such as a salve or an essential oil blend, follow the directions on the label.
From our Canada Balsam monograph — the full record covers uses, side effects and every documented interaction.
About Hydroxychloroquine
What Is Hydroxychloroquine Used For?
Brand name: Plaquenil
Hydroxychloroquine tablets are used to treat uncomplicated malaria and to help prevent malaria in areas where the parasite has not developed resistance to it — in both adults and children. It is also used in adults to treat rheumatoid arthritis, systemic lupus erythematosus (SLE), and chronic discoid lupus erythematosus.
There are important limits: it is not recommended for complicated or drug-resistant malaria, malaria acquired in regions where resistance is known, or to prevent malaria relapses caused by P. vivax or P. ovale. Its use for the autoimmune conditions (rheumatoid arthritis and lupus) is approved for adults only.
Other Drugs & Canada Balsam
Browse every other medication we’ve checked against Canada Balsam — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Canada Balsam against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Aspirin ›
- Abemaciclib ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Tadalafil ›
- Tirzepatide ›
- Methamphetamine ›
- Ibuprofen ›
- Valacyclovir ›
- Warfarin Sodium ›
- Hydroxyurea ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Isotretinoin ›
- Lisinopril ›
- Amlodipine Besylate ›
- Methotrexate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Doxycycline ›
- Fluoxetine ›
- Acyclovir ›
- Azithromycin ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Levothyroxine, Liothyronine ›
- Clonazepam ›
- Quetiapine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Duloxetine ›
- Methylene Blue ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Canada Balsam list.
Sources & How We Checked
We checked Canada Balsam against Hydroxychloroquine in the Natural Medicines interaction database and found no documented interaction on file. The medication overview comes from MedlinePlus, and supplement label details from the NIH Dietary Supplement Label Database.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference for vitamins, herbs and supplements — the basis for our interaction data.
- MedlinePlus, U.S. National Library of Medicine — NIH consumer drug information, used for the medication overviews.
- NIH Dietary Supplement Label Database (DSLD) — Official supplement product labels.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Taking Canada Balsam and Hydroxychloroquine Together: Common Questions
Is it safe to take Canada Balsam with Hydroxychloroquine?
Should I take Canada Balsam and Hydroxychloroquine at the same time of day?
Does Hydroxychloroquine interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Still Have a Question About Hydroxychloroquine and Canada Balsam?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.