Drug & supplement interaction

Cha De Bugre + Ponatinib

Ponatinib brand name: Iclusig.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 27, 2026
The bottom line No known interaction

We found no known interaction between Cha De Bugre and Ponatinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Cha De Bugre and Ponatinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ponatinib and Cha De Bugre in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Cha De Bugre at all — not against Ponatinib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Cha De Bugre safety at a glance

Cha De Bugre overall Use caution Limited human safety data and possible stimulant effects mean it should be used cautiously.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid Safety while breastfeeding is unknown, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ponatinib and Cha De Bugre? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Ponatinib’s Own FDA Label Lists

This is not an interaction — none of it involves Cha De Bugre. These are the most notable effects listed in the ADVERSE REACTIONS section of Ponatinib’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • A change in thyroid levels Worth acting on
  • Dehydration Worth acting on
  • Bleeding in the gut Worth acting on
  • A heart attack Worth acting on
  • Blood clots Worth acting on
  • Pancreatitis Worth acting on
  • Heart failure Worth acting on
  • High blood sugar Worth acting on
  • An irregular heartbeat Worth acting on
  • A severe skin reaction Worth acting on

Showing the 10 most notable of 49 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Ponatinib. Read the label on DailyMed › Cha De Bugre’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Cha De Bugre side to compare — that is a limit of the record, not a statement that Cha De Bugre has no side effects.

Everything else you take

See Every Supplement That Interacts With Ponatinib

This page covers Cha De Bugre only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ponatinib page lists 168 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).

By severity: 6 major · 124 moderate · 38 minor.

From our pharmacist’s overview on the Ponatinib page

“Ordinary grapefruit can drive up blood levels of ponatinib (Iclusig), the targeted leukemia medicine this page covers, because it blocks the CYP3A4 enzyme that clears the drug. St.”

Reviewed by 2 · Jul 18, 2026

Open the Ponatinib interaction page

One more smart check

Taking Cha De Bugre as Part of a Dietary Supplement Product? Check It for Interactions

We hold 62 real supplement products containing Cha De Bugre, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Cha De Bugre. Even though Cha De Bugre itself has no known interaction with Ponatinib, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Cha De Bugre and Ponatinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Cha De Bugre
Steady interest

#855 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ponatinib
Steady interest

#1,979 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources.
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Cha De Bugre and Ponatinib records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Cha De Bugre

What is Cha De Bugre?

  • Weight loss
  • Appetite control
  • Mild diuretic (water retention)
  • Cellulite
  • Energy and stimulation

Cha De Bugre is a Brazilian herbal tea traditionally used for weight loss and appetite control, but solid human research supporting these uses is lacking. Because it may have caffeine-like stimulant effects and its safety has not been well studied, talk with your pharmacist or doctor before trying it, and avoid it during pregnancy and breastfeeding.

Cordia salicifolia · Boraginaceae · Leaves · Tea, capsules, liquid extract

An interaction check asks whether these two react with each other — it does not ask whether Cha De Bugre is a good idea for someone in your situation. Here is what our Cha De Bugre record says about it on its own.

Cha De Bugre: dosing

There is no well-established or standardized dose for Cha De Bugre. The strength of teas, capsules, and extracts can vary widely from product to product.If you choose to use it, follow the directions on the product label and do not exceed the suggested amount.

From our Cha De Bugre monograph — the full record covers uses, side effects and every documented interaction.

Read the full Cha De Bugre monograph & all interactions
Medication

About Ponatinib

What Is Ponatinib Used For?

Brand name: Iclusig

Iclusig (ponatinib) is used to treat adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) — either newly diagnosed (in combination with chemotherapy) or in patients for whom no other kinase inhibitors are appropriate, or who have a specific mutation called T315I. It is also used for adults with chronic myeloid leukemia (CML), including chronic phase, accelerated phase, and blast phase CML, in situations where prior treatments have not worked or are not tolerated, or where the T315I mutation is present.

Iclusig is not recommended for patients newly diagnosed with chronic phase CML who have not yet tried other treatments.

See full Ponatinib drug information
Keep checking

Other Drugs & Cha De Bugre

Browse every other medication we’ve checked against Cha De Bugre — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Cha De Bugre against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Cha De Bugre list.

See the full Cha De Bugre interactions page
See every supplement checked against Ponatinib, ranked by severity
Sources

Sources & How We Checked

We checked Cha De Bugre against Ponatinib in the Natural Medicines interaction database and found no documented interaction on file. The medication overview comes from MedlinePlus, and supplement label details from the NIH Dietary Supplement Label Database.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Cha De Bugre monograph › Uses, safety, and every drug interaction in one place Ponatinib supplement interactions › Every supplement checked against Ponatinib, ranked by severity Ponatinib drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Cha De Bugre and Ponatinib Together: Common Questions

Is it safe to take Cha De Bugre with Ponatinib?
We do not list a known interaction between Cha De Bugre and Ponatinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Ponatinib interact with any supplements?
Yes. Ponatinib has documented interactions with 168 supplements in our database — Cha De Bugre is not one of them. The Ponatinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Ponatinib and Cha De Bugre?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.