Clematis Recta + Palovarotene
Palovarotene brand name: Sohonos.
We found no known interaction between Clematis Recta and Palovarotene in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Palovarotene states a food rule worth keeping to.
Clematis Recta and Palovarotene
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Palovarotene and Clematis Recta in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Clematis Recta at all — not against Palovarotene, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Clematis Recta safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Clematis Recta in Pregnancy & Breastfeeding
When the fresh plant is used orally. There is insufficient reliable information available for the safety of the dried plant; avoid using.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
Some Palovarotene Products Have a Food Rule — Clematis Recta Should Not Break It
At least one FDA label for a product containing Palovarotene says to take it with food. If you take Clematis Recta on an empty stomach out of habit, keep them separate — and take Palovarotene with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Palovarotene products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
Refer to Table 1 in Full Prescribing Information for complete pediatric dosing ( 2.2 ) Take SOHONOS with food preferably at same time each day ( 2.3 ).
From the Dosage and Administration section of the FDA label we read for Palovarotene — where that label names a specific product, the instruction is that product's. See the Palovarotene drug page ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
See Every Supplement That Interacts With Palovarotene
This page covers Clematis Recta only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Palovarotene page lists 138 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).
By severity: 3 major · 94 moderate · 41 minor.
From our pharmacist’s overview on the Palovarotene page
“Palovarotene (Sohonos) treats fibrodysplasia ossificans progressiva, a rare disease where soft tissue gradually turns to bone, and because it is cleared almost entirely by one liver enzyme, CYP3A4, supplement choices genuinely matter here. Three of the 138 ingredients on record rate major: grapefruit can drive palovarotene levels and i…”
Reviewed by 2 · Jul 18, 2026
Where Clematis Recta and Palovarotene Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#986 of 1,452 supplements looked up here in the last 7 days
#1,791 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Clematis Recta reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Clematis Recta and Palovarotene records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Clematis Recta
What is Clematis Recta?
- Skin complaints and eruptions
- Swollen or tender lymph glands
- Urinary discomfort
- Nerve pain
- Men's groin and testicular discomfort (traditional homeopathic use)
Clematis recta is a flowering plant in the buttercup family that is mostly sold today as a homeopathic remedy. The fresh plant is toxic and irritating, and there is no reliable human evidence that it treats any condition, so it should be used cautiously and only under professional guidance.
Clematis recta · Ranunculaceae · Fresh leaves and stems (aerial parts), usually gathered before flowering · Homeopathic pellets, dilutions, and mother tinctures; rarely as topical preparations
An interaction check asks whether these two react with each other — it does not ask whether Clematis Recta is a good idea for someone in your situation. Here is what our Clematis Recta record says about it on its own.
Clematis Recta: dosing
There is no established standard dose for Clematis recta. The raw plant is not recommended at all because it is toxic and irritating.When sold as a homeopathic remedy, it comes in standardized dilutions and potencies set by the manufacturer.
From our Clematis Recta monograph — the full record covers uses, side effects and every documented interaction.
About Palovarotene
What Is Palovarotene Used For?
Brand name: Sohonos
Palovarotene (brand name Sohonos) is used to reduce the volume of new heterotopic ossification, which is bone growing where it shouldn't, in people with fibrodysplasia ossificans progressiva (FOP).
It is approved for adults and for children aged 8 years and older for females and 10 years and older for males.
Most-Reported Side Effects for Palovarotene
From FAERS, the FDA’s public side-effect reporting system (57 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Clematis Recta
Browse every other medication we’ve checked against Clematis Recta — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Clematis Recta against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Abemaciclib ›
- Ivermectin ›
- Testosterone ›
- Sertraline ›
- Losartan Potassium ›
- Acetaminophen ›
- Aspirin ›
- Rosuvastatin ›
- Escitalopram ›
- Metoprolol ›
- Clopidogrel ›
- Rivaroxaban ›
- Atorvastatin ›
- Isotretinoin ›
- Warfarin Sodium ›
- Tirzepatide ›
- Amlodipine Besylate ›
- Ibuprofen ›
- Methamphetamine ›
- Docusate ›
- Tadalafil ›
- Hydroxyurea ›
- Valacyclovir ›
- Metformin ›
- Sumatriptan ›
- Prednisone ›
- Semaglutide ›
- Amitriptyline ›
- Lisdexamfetamine ›
- Amphetamine ›
- Levothyroxine, Liothyronine ›
- Propranolol ›
- Methotrexate ›
- Amoxicillin ›
- Lisinopril ›
- Bupropion ›
- Fluoxetine ›
- Azithromycin ›
- Bendamustine ›
- Pregabalin ›
- Doxycycline ›
- Gabapentin ›
- Dextroamphetamine ›
- Lamotrigine ›
- Acyclovir ›
- Naproxen ›
- Acetaminophen, Aspirin, Caffeine ›
- Quetiapine ›
- Clonazepam ›
- Buspirone ›
- Omeprazole ›
- Duloxetine ›
- Letrozole ›
- Citalopram ›
- Methylene Blue ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Clematis Recta list.
Clematis Recta References
The 1 references that drive our Clematis Recta monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Clematis Recta and Palovarotene Together: Common Questions
Is it safe to take Clematis Recta with Palovarotene?
Should I take Clematis Recta and Palovarotene at the same time of day?
Does Palovarotene interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Palovarotene and Clematis Recta?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.