Drug & supplement interaction

Elemi + Glecaprevir, Pibrentasvir

Glecaprevir, Pibrentasvir brand name: Mavyret.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Elemi and Glecaprevir, Pibrentasvir in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Glecaprevir, Pibrentasvir states a food rule worth keeping to.

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Interaction report

Elemi and Glecaprevir, Pibrentasvir

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Glecaprevir, Pibrentasvir and Elemi in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Elemi at all — not against Glecaprevir, Pibrentasvir, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Elemi safety at a glance

Elemi overall Use caution Generally used topically or aromatically with dilution; ingesting the essential oil is not considered safe.
Pregnancy Avoid Not enough safety data, so avoid during pregnancy.
Breastfeeding Avoid Not enough safety data, so avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Glecaprevir, Pibrentasvir and Elemi? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Glecaprevir, Pibrentasvir’s Own FDA Label Lists

This is not an interaction — none of it involves Elemi. These are the most notable effects listed in the ADVERSE REACTIONS section of Glecaprevir, Pibrentasvir’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 5 of them are worth acting on rather than waiting out — marked below.

  • Yellowing of the skin or eyes Worth acting on
  • Kidney problems Worth acting on
  • A severe allergic reaction Worth acting on
  • Liver problems Worth acting on
  • A higher chance of infection Worth acting on
  • Tiredness mentioned in 23.5% of FDA reports for Glecaprevir, Pibrentasvir
  • Headache mentioned in 20.2% of FDA reports for Glecaprevir, Pibrentasvir
  • Itching mentioned in 6.0% of FDA reports for Glecaprevir, Pibrentasvir
  • Stomach pain
  • Nausea mentioned in 10.4% of FDA reports for Glecaprevir, Pibrentasvir

Showing the 10 most notable of 13 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Glecaprevir, Pibrentasvir. Read the label on DailyMed › Where a percentage is shown, it is the share of 10,923 voluntary FDA FAERS reports for Glecaprevir, Pibrentasvir that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Elemi’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Elemi side to compare — that is a limit of the record, not a statement that Elemi has no side effects.

How to take them

Some Glecaprevir, Pibrentasvir Products Have a Food Rule — Elemi Should Not Break It

At least one FDA label for a product containing Glecaprevir, Pibrentasvir says to take it with food. If you take Elemi on an empty stomach out of habit, keep them separate — and take Glecaprevir, Pibrentasvir with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Glecaprevir, Pibrentasvir products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Recommended dosage in adults: Three tablets taken at the same time orally once daily (total daily dose: glecaprevir 300 mg and pibrentasvir 120 mg) with food.

From the Dosage and Administration section of the FDA label we read for Glecaprevir, Pibrentasvir — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Glecaprevir, Pibrentasvir

This page covers Elemi only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Glecaprevir, Pibrentasvir page lists 144 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 103 moderate · 38 minor.

From our pharmacist’s overview on the Glecaprevir, Pibrentasvir page

“Mavyret (glecaprevir and pibrentasvir) is a short course of pills meant to cure hepatitis C, so I read its supplement list with real caution. Nearly everything on it can shift how much of the drug reaches your blood, mostly through the CYP3A4 enzyme or the P-glycoprotein transporter that handles it.”

Reviewed by 2 · Jul 18, 2026

Open the Glecaprevir, Pibrentasvir interaction page

One more smart check

Taking Elemi as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Elemi, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Elemi. Even though Elemi itself has no known interaction with Glecaprevir, Pibrentasvir, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Elemi and Glecaprevir, Pibrentasvir Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Elemi
Steady interest

#1,279 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Glecaprevir, Pibrentasvir
Steady interest

#2,708 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Elemi is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Elemi reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Elemi and Glecaprevir, Pibrentasvir records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Elemi

What is Elemi?

  • Skin care and wound soothing
  • Aromatherapy for relaxation
  • Cough and chest congestion
  • Muscle and joint discomfort
  • Antimicrobial use (topical)

Elemi is a fragrant tree resin from the Philippines, used mainly as an essential oil in aromatherapy and topical skin and balm products. Solid human evidence for any health benefit is lacking, and like other essential oils it should never be swallowed and should be diluted before skin use. Talk to a pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have sensitive skin.

Canarium luzonicum · Burseraceae · Oleoresin (gum resin) and the essential oil distilled from it · Essential oil, resin, and ingredient in salves, balms, and incense

An interaction check asks whether these two react with each other — it does not ask whether Elemi is a good idea for someone in your situation. Here is what our Elemi record says about it on its own.

Elemi: dosing

There is no established or standardized dose for elemi. For aromatherapy and topical use, the right amount depends on the product and how it is blended. Essential oils are typically diluted to a low percentage in a carrier oil before being applied to skin.Follow the directions on the specific product label, and do not assume more is better.

From our Elemi monograph — the full record covers uses, side effects and every documented interaction.

Read the full Elemi monograph & all interactions
Medication

About Glecaprevir and Pibrentasvir

What Is Glecaprevir and Pibrentasvir Used For?

Brand name: Mavyret

Mavyret treats acute or chronic hepatitis C virus (HCV) infection caused by genotypes 1, 2, 3, 4, 5, or 6 in adults and children 3 years and older who have no cirrhosis or have compensated cirrhosis (mild liver scarring that is still functioning).

Mavyret is also approved for adults and children 3 years and older with genotype 1 HCV who were previously treated with either an NS5A inhibitor or an NS3/4A protease inhibitor (two earlier classes of hepatitis C drugs) — but not both at the same time.

See full Glecaprevir and Pibrentasvir drug information
Keep checking

Other Drugs & Elemi

Browse every other medication we’ve checked against Elemi — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Elemi against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Elemi list.

See the full Elemi interactions page
See every supplement checked against Glecaprevir, Pibrentasvir, ranked by severity
Evidence & sources

Elemi References

The 1 sources that drive our Elemi monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Elemi is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Aromatherapy — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Elemi and Glecaprevir, Pibrentasvir Together: Common Questions

Is it safe to take Elemi with Glecaprevir, Pibrentasvir?
We do not list a known interaction between Elemi and Glecaprevir, Pibrentasvir. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Elemi and Glecaprevir, Pibrentasvir at the same time of day?
At least one FDA label for a product containing Glecaprevir, Pibrentasvir says to take it with food. If you take Elemi on an empty stomach out of habit, keep them separate and take Glecaprevir, Pibrentasvir with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Glecaprevir, Pibrentasvir products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Glecaprevir, Pibrentasvir interact with any supplements?
Yes. Glecaprevir, Pibrentasvir has documented interactions with 144 supplements in our database — Elemi is not one of them. The Glecaprevir, Pibrentasvir interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Elemi monograph Uses, safety profile, and every drug interaction in one place Glecaprevir and Pibrentasvir drug information The full plain-English guide to this medication Glecaprevir, Pibrentasvir supplement interactions Every supplement checked against Glecaprevir, Pibrentasvir, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Glecaprevir, Pibrentasvir and Elemi?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.