Drug & supplement interaction

Elemi + Mirtazapine

Mirtazapine brand name: Remeron.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Elemi and Mirtazapine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Elemi and Mirtazapine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Mirtazapine and Elemi in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Elemi at all — not against Mirtazapine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Elemi safety at a glance

Elemi overall Use caution Generally used topically or aromatically with dilution; ingesting the essential oil is not considered safe.
Pregnancy Avoid Not enough safety data, so avoid during pregnancy.
Breastfeeding Avoid Not enough safety data, so avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Mirtazapine and Elemi? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Mirtazapine’s Own FDA Label Lists

This is not an interaction — none of it involves Elemi. These are the most notable effects listed in the ADVERSE REACTIONS section of Mirtazapine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Mania or an unusually elevated mood Worth acting on
  • A change in thyroid levels Worth acting on
  • Dependence or withdrawal symptoms Worth acting on
  • Serotonin syndrome Worth acting on
  • Thoughts of self-harm Worth acting on
  • Hearing loss Worth acting on
  • A bowel blockage Worth acting on
  • Bone thinning Worth acting on
  • Pain or burning when passing urine Worth acting on
  • Severe muscle breakdown Worth acting on

Showing the 10 most notable of 81 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Mirtazapine. Read the label on DailyMed › Elemi’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Elemi side to compare — that is a limit of the record, not a statement that Elemi has no side effects.

From our Q&A

Questions About Elemi or Mirtazapine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Elemi or Mirtazapine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Mirtazapine

This page covers Elemi only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Mirtazapine page lists 212 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), Lithium (major), St. John's Wort (major) and 1,3-dmaa (moderate).

By severity: 4 major · 162 moderate · 46 minor.

From our pharmacist’s overview on the Mirtazapine page

“Depression and poor sleep tend to travel together, which is why people on mirtazapine (Remeron) so often eye herbal mood and sleep remedies, and that overlap is exactly where this list demands real care. Four of the 212 ingredients on file carry a major rating.”

Reviewed by 2 · Jul 18, 2026

Open the Mirtazapine interaction page

One more smart check

Taking Elemi as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Elemi, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Elemi. Even though Elemi itself has no known interaction with Mirtazapine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Elemi and Mirtazapine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Elemi
Steady interest

#1,043 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Mirtazapine
Top 25%

#300 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Elemi is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Elemi reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Elemi and Mirtazapine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Elemi

What is Elemi?

  • Skin care and wound soothing
  • Aromatherapy for relaxation
  • Cough and chest congestion
  • Muscle and joint discomfort
  • Antimicrobial use (topical)

Elemi is a fragrant tree resin from the Philippines, used mainly as an essential oil in aromatherapy and topical skin and balm products. Solid human evidence for any health benefit is lacking, and like other essential oils it should never be swallowed and should be diluted before skin use. Talk to a pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have sensitive skin.

Canarium luzonicum · Burseraceae · Oleoresin (gum resin) and the essential oil distilled from it · Essential oil, resin, and ingredient in salves, balms, and incense

An interaction check asks whether these two react with each other — it does not ask whether Elemi is a good idea for someone in your situation. Here is what our Elemi record says about it on its own.

Elemi: dosing

There is no established or standardized dose for elemi. For aromatherapy and topical use, the right amount depends on the product and how it is blended. Essential oils are typically diluted to a low percentage in a carrier oil before being applied to skin.Follow the directions on the specific product label, and do not assume more is better.

From our Elemi monograph — the full record covers uses, side effects and every documented interaction.

Read the full Elemi monograph & all interactions
Medication

About Mirtazapine

What Is Mirtazapine Used For?

Brand name: Remeron

Mirtazapine is used to treat major depressive disorder (MDD), commonly called clinical depression. The mirtazapine tablet and orally disintegrating tablet labels, including Remeron and RemeronSolTab, state use in adults.

In studies, it worked in six-week trials, and one trial showed the benefit lasted for up to 40 weeks in people who had already responded. Doctors should periodically re-check whether longer-term use is still helping.

See full Mirtazapine drug information
Keep checking

Other Drugs & Elemi

Browse every other medication we’ve checked against Elemi — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Elemi References

The 1 sources that drive our Elemi monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Elemi is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Aromatherapy — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Elemi and Mirtazapine Together: Common Questions

Is it safe to take Elemi with Mirtazapine?
We do not list a known interaction between Elemi and Mirtazapine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Mirtazapine interact with any supplements?
Yes. Mirtazapine has documented interactions with 212 supplements in our database — Elemi is not one of them. The Mirtazapine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Mirtazapine and Elemi?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.