Drug & supplement interaction

European Chestnut + Auranofin

Auranofin brand name: Ridaura.

No Known Interaction
The bottom line No known interaction

We found no known interaction between European Chestnut and Auranofin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

European Chestnut and Auranofin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Auranofin and European Chestnut in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for European Chestnut at all — not against Auranofin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

European Chestnut safety at a glance

European Chestnut overall Use caution The nut is a common food, but concentrated leaf or bark extracts have not been well studied for safety.
Pregnancy Avoid There is not enough safety information, so medicinal use during pregnancy is best avoided.
Breastfeeding Avoid Safety during breastfeeding is unknown, so medicinal use is best avoided.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Auranofin and European Chestnut? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Auranofin’s Own FDA Label Lists

This is not an interaction — none of it involves European Chestnut. These are the most notable effects listed in the ADVERSE REACTIONS section of Auranofin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Trouble swallowing Worth acting on
  • Bleeding in the gut Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • A low platelet count Worth acting on
  • Kidney problems Worth acting on
  • Anemia Worth acting on
  • A severe allergic reaction Worth acting on
  • Hives Worth acting on
  • A low white blood cell count Worth acting on
  • Liver problems Worth acting on

Showing the 10 most notable of 26 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Auranofin. Read the label on DailyMed › European Chestnut’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no European Chestnut side to compare — that is a limit of the record, not a statement that European Chestnut has no side effects.

Everything else you take

See Every Supplement That Interacts With Auranofin

This page covers European Chestnut only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Auranofin page lists 37 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Alfalfa (moderate), Angelica Archangelica (moderate), Arrach (moderate) and Bergamot (moderate).

By severity: 1 major · 26 moderate · 10 minor.

From our pharmacist’s overview on the Auranofin page

“Auranofin (Ridaura) is a gold compound taken by mouth for rheumatoid arthritis, and its interaction list deserves real respect rather than a quick skim. Two patterns run through nearly everything on it.”

Reviewed by 2 · Jul 18, 2026

Open the Auranofin interaction page

How much people look this up

Where European Chestnut and Auranofin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement European Chestnut
Steady interest

#1,167 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Auranofin
Steady interest

#2,612 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every European Chestnut reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The European Chestnut and Auranofin records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About European Chestnut

What is European Chestnut?

  • Coughs and respiratory irritation
  • Diarrhea and digestive upset
  • Sore throat
  • Wound and skin care
  • General antioxidant support

European Chestnut is a tree whose leaves and nuts have a long history of use for coughs, diarrhea, and skin care, mostly in traditional folk medicine. High-quality human studies are lacking, so its benefits remain unproven, and it should be used cautiously and discussed with a pharmacist or doctor.

Castanea sativa · Fagaceae · Leaves, nuts (seeds), bark, and flowers · Tea, liquid extract, capsules, honey, and topical preparations

An interaction check asks whether these two react with each other — it does not ask whether European Chestnut is a good idea for someone in your situation. Here is what our European Chestnut record says about it on its own.

European Chestnut: dosing

There is no standardized or well-established medicinal dose for European Chestnut. Products vary widely in strength and in which part of the plant they use.If you choose to use a chestnut product, follow the directions on the label and do not exceed the recommended amount.

From our European Chestnut monograph — the full record covers uses, side effects and every documented interaction.

Read the full European Chestnut monograph & all interactions
Medication

About Auranofin

What Is Auranofin Used For?

Brand name: Ridaura

Auranofin capsules — sold as both Ridaura and Auranofin — are used to manage active rheumatoid arthritis in adults. Specifically, they're for people whose arthritis hasn't improved enough with full doses of nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen, or who couldn't tolerate those medicines.

It works best alongside a full treatment program — not as a stand-alone fix. It's important to know that it doesn't work quickly: you may not notice improvement for three to six months, and it cannot reverse joint or bone damage that has already occurred.

See full Auranofin drug information
Keep checking

Other Drugs & European Chestnut

Browse every other medication we’ve checked against European Chestnut — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

European Chestnut References

The 1 references that drive our European Chestnut monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking European Chestnut and Auranofin Together: Common Questions

Is it safe to take European Chestnut with Auranofin?
We do not list a known interaction between European Chestnut and Auranofin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Auranofin interact with any supplements?
Yes. Auranofin has documented interactions with 37 supplements in our database — European Chestnut is not one of them. The Auranofin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Auranofin and European Chestnut?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.