Drug & supplement interaction

Greek Sage + tipranavir

tipranavir brand name: Aptivus.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Greek Sage and tipranavir in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for tipranavir states a food rule worth keeping to.

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Interaction report

Greek Sage and tipranavir

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between tipranavir and Greek Sage in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Greek Sage safety at a glance

Greek Sage overall Use caution Likely safe in food and tea amounts, but concentrated extracts and the essential oil need more caution.
Pregnancy Avoid Avoid medicinal or concentrated amounts during pregnancy due to limited safety data.
Breastfeeding Use caution Limited data; avoid concentrated forms and check with your doctor.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining tipranavir and Greek Sage? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for tipranavir

Interactions in our licensed database are recorded against drug classes, not just single drug names. tipranavir is filed under 11 classifications — including protease inhibitors (pis), cytochrome p450 2c19 (cyp2c19) substrates, cytochrome p450 3a4 (cyp3a4) inducers. Greek Sage has documented interactions with 1 drug class — the most serious being hexobarbital (moderate) — and none of tipranavir’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Greek Sage Does Interact With Other Medications

Greek Sage has 1 moderate known drug interaction in our database — tipranavir isn’t one of them. If you take anything else, check it against the full list below.

Moderate 1 No known interaction 2,829 (incl. tipranavir)
Taking anything else?

Check Another of Your Medications Against Greek Sage

Covers the 2,830 medications we’ve checked against Greek Sage. Pick one to open its full report.

What to actually watch for

What tipranavir’s Own FDA Label Lists

This is not an interaction — none of it involves Greek Sage. These are the most notable effects listed in the ADVERSE REACTIONS section of tipranavir’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 5 of them are worth acting on rather than waiting out — marked below.

  • Dehydration Worth acting on
  • Anemia Worth acting on
  • Shortness of breath Worth acting on
  • A low white blood cell count Worth acting on
  • Bleeding or bruising Worth acting on
  • Weight loss
  • Vomiting mentioned in 19.9% of FDA reports for tipranavir
  • Nausea mentioned in 20.5% of FDA reports for tipranavir
  • Numbness or tingling
  • Muscle pain

Showing the 10 most notable of 17 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for tipranavir. Read the label on DailyMed › Where a percentage is shown, it is the share of 1,379 voluntary FDA FAERS reports for tipranavir that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Greek Sage’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Greek Sage side to compare — that is a limit of the record, not a statement that Greek Sage has no side effects.

How to take them

Some tipranavir Products Have a Food Rule — Greek Sage Should Not Break It

At least one FDA label for a product containing tipranavir says to take it with food. If you take Greek Sage on an empty stomach out of habit, keep them separate — and take tipranavir with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two tipranavir products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

( 2.2 ) APTIVUS taken with ritonavir tablets must be taken with meals ( 2.1 ) APTIVUS capsules must be swallowed whole and must not be opened or chewed ( 2.1 ) Children should be assessed for their ability to swallow capsules before prescribing APTIVUS capsules.

From the Dosage and Administration section of the FDA label we read for tipranavir — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With tipranavir

This page covers Greek Sage only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the tipranavir page lists 212 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), 1,3-dmaa (moderate) and Acacia Rigidula (moderate).

By severity: 3 major · 165 moderate · 44 minor.

From our pharmacist’s overview on the tipranavir page

“Keeping tipranavir (Aptivus) at a steady blood level is what keeps HIV suppressed, so this is a supplement list that deserves genuine care, and the three major-rated entries come first. St.”

Reviewed by 2 · Jul 18, 2026

Open the tipranavir interaction page

How much people look this up

Where Greek Sage and tipranavir Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Greek Sage
Steady interest

#816 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication tipranavir
Steady interest

#1,728 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Greek Sage reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Greek Sage and tipranavir records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Greek Sage

What is Greek Sage?

  • Sore throat and mouth irritation
  • Digestive upset
  • Memory and cognition support
  • Antimicrobial purposes
  • Flavoring and aromatherapy

Greek sage (Salvia fruticosa) is a Mediterranean herb traditionally used as a tea and flavoring, and popularly for sore throats and digestion. Solid human research on its health benefits is limited, so most uses are based on tradition or early lab studies. It is generally considered safe in food amounts, but talk to a pharmacist or doctor before using concentrated extracts or essential oils.

Salvia fruticosa · Lamiaceae · Leaves and essential oil · Tea, dried leaf, capsules, essential oil, extracts

An interaction check asks whether these two react with each other — it does not ask whether Greek Sage is a good idea for someone in your situation. Here is what our Greek Sage record says about it on its own.

Greek Sage: dosing

There is no official standardized dose of Greek sage. Traditional use is usually a cup of tea made from a small amount of dried leaf.For capsules, extracts, or essential oil products, follow the directions on the label, since the strength varies a lot between products.

From our Greek Sage monograph — the full record covers uses, side effects and every documented interaction.

Read the full Greek Sage monograph & all interactions
Medication

About Tipranavir

What Is Tipranavir Used For?

Brand name: Aptivus

Aptivus (tipranavir) is used to treat HIV-1 infection in adults and in pediatric patients weighing at least 36 kg (about 79 lbs). It is specifically for people who have already tried other HIV treatments and whose virus has become resistant to more than one protease inhibitor. It is always taken together with a low dose of ritonavir and with other HIV medications.

Aptivus is not recommended for people who have never taken HIV treatment before (treatment-naïve patients). Using tipranavir alongside additional active HIV drugs improves the chances of it working well.

See full Tipranavir drug information
Keep checking

Other Drugs & Greek Sage

Browse every other medication we’ve checked against Greek Sage — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
1Moderate
0Minor
2,828No known interaction
1 Moderate 2,828 No interaction
Moderate

1 interaction

No interaction 2,828 drugs checked — show the list

We also checked Greek Sage against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,828 medications checked with no known interaction — see the full Greek Sage list.

See the full Greek Sage interactions page
See every supplement checked against tipranavir, ranked by severity
Evidence & sources

Greek Sage References

The 1 references that drive our Greek Sage monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Todorov S, Philianos S, Petkov V, et al. Experimental pharmacological study of three species from genus Salvia. Acta Physiol Pharmacol (Bulg) 1984;10:13-20.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Greek Sage and tipranavir Together: Common Questions

Is it safe to take Greek Sage with tipranavir?
We do not list a known interaction between Greek Sage and tipranavir. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Greek Sage and tipranavir at the same time of day?
At least one FDA label for a product containing tipranavir says to take it with food. If you take Greek Sage on an empty stomach out of habit, keep them separate and take tipranavir with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two tipranavir products can differ — so check the directions on your own box. This is about absorption, not an interaction.
How was the Greek Sage and tipranavir combination checked?
Interactions in our licensed database are recorded against drug classes. tipranavir is filed under 11 classifications, and Greek Sage has documented interactions with 1 drug class — none of tipranavir's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Greek Sage interact with any other medications?
Yes. Greek Sage has 1 documented drug interaction in our database — tipranavir is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does tipranavir interact with any supplements?
Yes. tipranavir has documented interactions with 212 supplements in our database — Greek Sage is not one of them. The tipranavir interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Greek Sage monograph Uses, safety profile, and every drug interaction in one place Tipranavir drug information The full plain-English guide to this medication tipranavir supplement interactions Every supplement checked against tipranavir, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About tipranavir and Greek Sage?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.