Drug & supplement interaction

Halodrol-50 + Tirbanibulin

Tirbanibulin brand name: Klisyri.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Halodrol-50 and Tirbanibulin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Halodrol-50 and Tirbanibulin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tirbanibulin and Halodrol-50 in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Halodrol-50 at all — not against Tirbanibulin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Halodrol-50 safety at a glance

Halodrol-50 overall Avoid It is a designer anabolic-type supplement linked to liver and hormonal harm, and some versions were banned.
Pregnancy Possibly Unsafe When used orally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, hair loss,... Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, hair loss,... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tirbanibulin and Halodrol-50? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Tirbanibulin’s Own FDA Label Lists

This is not an interaction — none of it involves Halodrol-50. These are the most notable effects listed in the ADVERSE REACTIONS section of Tirbanibulin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both.

  • Itching
  • Swelling

From the ADVERSE REACTIONS section of the FDA label for Tirbanibulin. Read the label on DailyMed › Halodrol-50’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Halodrol-50 side to compare — that is a limit of the record, not a statement that Halodrol-50 has no side effects.

Special populations

Halodrol-50 in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous. Avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Tirbanibulin

This page covers Halodrol-50 only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tirbanibulin page lists 3 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).

By severity: 2 moderate · 1 minor.

From our pharmacist’s overview on the Tirbanibulin page

“Topical DMSO is the one to know about if you use tirbanibulin (Klisyri), the ointment prescribed for actinic keratosis on the skin. DMSO can drive other topical drugs deeper through the skin, which could amplify both the medication's effect and its irritation right where it's applied.”

Reviewed by 2 · Jul 18, 2026

Open the Tirbanibulin interaction page

How much people look this up

Where Halodrol-50 and Tirbanibulin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Halodrol-50
Top half

#665 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tirbanibulin
Steady interest

#1,921 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Halodrol-50 reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Halodrol-50 and Tirbanibulin records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Halodrol-50

What is Halodrol-50?

  • Building muscle mass
  • Increasing strength
  • Bodybuilding and athletic performance
  • Body recomposition

Halodrol-50 is a brand-name 'prohormone' designer supplement, not an herb, that was marketed to build muscle and strength. Older versions contained synthetic anabolic steroid-like compounds that were later banned in the United States, and these substances carry real risks of liver injury and hormone disruption. Because product formulas have changed over time and ingredients can be unpredictable, we recommend avoiding it and talking with your pharmacist or doctor before using any prohormone product.

Not applicable (synthetic compound) · Tablets, capsules

An interaction check asks whether these two react with each other — it does not ask whether Halodrol-50 is a good idea for someone in your situation. Here is what our Halodrol-50 record says about it on its own.

Halodrol-50: dosing

There is no established safe or standardized dose for Halodrol-50, and we do not recommend using it.

From our Halodrol-50 monograph — the full record covers uses, side effects and every documented interaction.

Read the full Halodrol-50 monograph & all interactions
Medication

About Tirbanibulin Topical

What Is Tirbanibulin Topical Used For?

Brand name: Klisyri

Klisyri (tirbanibulin 1% ointment) is applied directly to the skin to treat actinic keratosis — rough, scaly patches caused by years of sun damage that can sometimes turn into skin cancer if left untreated. It is approved for use on the face or balding scalp in adults.

Klisyri is applied to the entire affected treatment area (up to a 100 cm² patch) rather than to individual spots, an approach called field treatment.

See full Tirbanibulin Topical drug information
Keep checking

Other Drugs & Halodrol-50

Browse every other medication we’ve checked against Halodrol-50 — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Halodrol-50 against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Halodrol-50 list.

See the full Halodrol-50 interactions page
See every supplement checked against Tirbanibulin, ranked by severity
Evidence & sources

Halodrol-50 References

The 1 references that drive our Halodrol-50 monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Halodrol-50 and Tirbanibulin Together: Common Questions

Is it safe to take Halodrol-50 with Tirbanibulin?
We do not list a known interaction between Halodrol-50 and Tirbanibulin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Tirbanibulin interact with any supplements?
Yes. Tirbanibulin has documented interactions with 3 supplements in our database — Halodrol-50 is not one of them. The Tirbanibulin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Halodrol-50 monograph Uses, safety profile, and every drug interaction in one place Tirbanibulin Topical drug information The full plain-English guide to this medication Tirbanibulin supplement interactions Every supplement checked against Tirbanibulin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Tirbanibulin and Halodrol-50?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.