Hibiscus Sabdariffa - Topotecan Interaction
Herbal: Hibiscus Sabdariffa
Also Known As: Hibiscus sabdariffa, Agua de Jamaica, Ambashthaki, Bissap, Erragogu, Flor de Jamaica, Florida cranberry, Gongura, Groseille de Guinée, Guinea Sorrel, Hibisco, Hibiscus Calyx, Jamaica Sorrel, Karkade, Karkadé, Kenaf, Lo Shen, Oseille de Guinée, Oseille Rouge
Drug: Topotecan
Brand names:
Hycamtin
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 25, 2025
Interaction Details
There were no interactions found between Topotecan and Hibiscus Sabdariffa. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Hibiscus Sabdariffa Overview
Hibiscus sabdariffa, also known as roselle or red sorrel, is a plant that belongs to the Malvaceae family and is native to several tropical regions of the world, including Africa, Asia, and the Caribbean. It is a perennial plant that has large flowers and a tart, cranberry-like flavor. It is a popular ingredient in beverages and is rich in antioxidants, vitamins and minerals, including vitamin C, calcium, and iron. Hibiscus sabdariffa is used in traditional medicine and is claimed to have a number of potential health benefits, including reducing blood pressure, improving digestion, and relieving stress and anxiety. It has also been used for improving liver health as well as a fever-reducer.
Topotecan Overview
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Topotecan is used to treat small cell lung cancer (a type of cancer that begins in the lungs) that was successfully treated with a different chemotherapy medication but has returned no sooner than 45 days after the last dose of the first chemotherapy medication was taken. Topotecan is in a class of medications called topoisomerase I inhibitors. It works by killing cancer cells.
Hibiscus Sabdariffa - More Interactions
Hibiscus Sabdariffa interacts with 1058 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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