Drug & supplement interaction

Javanese Turmeric + Naloxone

Naloxone brand names: Narcan, Zimhi, Rivive.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Javanese Turmeric and Naloxone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

Know someone taking this? Share
Interaction report

Javanese Turmeric and Naloxone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Naloxone and Javanese Turmeric in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Javanese Turmeric safety at a glance

Javanese Turmeric overall Use caution Generally well tolerated in food-like amounts, but human safety data for concentrated supplements are limited.
Pregnancy Avoid Not enough safety data, so it is best avoided during pregnancy.
Breastfeeding Avoid Safety while breastfeeding is unknown, so avoiding it is the safer choice.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Naloxone and Javanese Turmeric? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Naloxone

Interactions in our licensed database are recorded against drug classes, not just single drug names. Naloxone is filed under a single classification. Javanese Turmeric has documented interactions with 1 drug class — the most serious being warfarin (coumadin) (moderate) — and none of Naloxone’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Javanese Turmeric Does Interact With Other Medications

Javanese Turmeric has 2 moderate known drug interactions in our database — Naloxone isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Javanese Turmeric

Covers the 2,830 medications we’ve checked against Javanese Turmeric. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Javanese Turmeric and Naloxone May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Nausea Additional detail

    Javanese Turmeric

    “Orally, Javanese turmeric can cause gastric irritation and nausea when used in large amounts or for prolonged periods of time (2,8).”

    Javanese Turmeric · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    2 sources cited
    1. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
    2. 8. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.

    Naloxone

    Listed in the ADVERSE REACTIONS section of the FDA label for Naloxone. Read the label on DailyMed ›

Reported for Javanese Turmeric but not commonly for Naloxone: stomach upset.

Effects for Naloxone come from the ADVERSE REACTIONS section of its FDA label; effects for Javanese Turmeric come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Everything else you take

See Every Supplement That Interacts With Naloxone

This page covers Javanese Turmeric only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Naloxone page lists 3 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (moderate), Gamma Butyrolactone (gbl) (moderate) and Gamma-hydroxybutyrate (ghb) (moderate).

By severity: 3 moderate.

From our pharmacist’s overview on the Naloxone page

“The list of supplements that interact with naloxone, the emergency spray or injection (Narcan, Zimhi, Rivive) that reverses opioid overdoses, is short and unusual. All three entries are forms of the same substance: gamma-hydroxybutyrate (GHB) and two chemicals the body converts into it, GBL and 1,4-butanediol.”

Reviewed by 2 · Jul 18, 2026

Open the Naloxone interaction page

One more smart check

Taking Javanese Turmeric as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Javanese Turmeric, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Javanese Turmeric. Even though Javanese Turmeric itself has no known interaction with Naloxone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Javanese Turmeric and Naloxone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Javanese Turmeric
Steady interest

#1,327 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Naloxone
Top 25%

#457 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Javanese Turmeric reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Javanese Turmeric and Naloxone records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Javanese Turmeric

What is Javanese Turmeric?

  • Digestive upset and bloating
  • Liver and gallbladder support
  • Loss of appetite
  • Joint and inflammation complaints
  • General wellness tonic

Javanese turmeric (Curcuma zanthorrhiza), known in Indonesia as temulawak, is a ginger-family root traditionally used for digestive and liver complaints. Early lab and animal studies are interesting, but strong human evidence is limited, so it should be viewed as a traditional remedy rather than a proven treatment. Talk to a pharmacist or doctor before using it, especially if you have a health condition or take medications.

Curcuma zanthorrhiza · Zingiberaceae · Rhizome (root) · Capsules, tablets, powder, dried root, tea, liquid extracts

An interaction check asks whether these two react with each other — it does not ask whether Javanese Turmeric is a good idea for someone in your situation. Here is what our Javanese Turmeric record says about it on its own.

Javanese Turmeric: dosing

There is no well-established standardized dose for Javanese turmeric. Products vary widely in strength and form, and the active compounds are absorbed differently from one preparation to another.The safest approach is to follow the directions on the product label and not exceed the recommended amount.

From our Javanese Turmeric monograph — the full record covers uses, side effects and every documented interaction.

Read the full Javanese Turmeric monograph & all interactions
Medication

About Naloxone Injection

What Is Naloxone Injection Used For?

Brand names: Narcan, Zimhi, Rivive

Naloxone Hydrochloride injection is used for the emergency treatment of known or suspected opioid overdose — reversing dangerous slowing of breathing and loss of consciousness caused by opioids. It is also approved for use in pediatric patients of all ages.

Naloxone Hydrochloride injection is additionally indicated specifically for military personnel and chemical incident responders: for emergency treatment of patients 12 and older where high-potency opioids such as fentanyl analogues have been used as a chemical weapon, and for temporary protection against breathing and nervous system depression when entering an area contaminated with such opioids. Zimhi (naloxone HCl) is a pre-filled, single-dose injectable product approved for intramuscular or subcutaneous use in known or suspected opioid overdose.

See full Naloxone Injection drug information
Keep checking

Other Drugs & Javanese Turmeric

Browse every other medication we’ve checked against Javanese Turmeric — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
2Moderate
0Minor
2,827No known interaction
Moderate

2 interactions

No interaction 2,827 drugs checked — show the list
Evidence & sources

Javanese Turmeric References

The 3 references that drive our Javanese Turmeric monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
  3. Rusdiana T, Mardhiani YD, Putriana NA, et al. The influence of Javanese turmeric (Curcuma xanthorrhiza) on the pharmacokinetics of warfarin in rats with single and multiple-dose studies. Pharm Biol. 2021;59(1):639-646.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Javanese Turmeric and Naloxone Together: Common Questions

Is it safe to take Javanese Turmeric with Naloxone?
We do not list a known interaction between Javanese Turmeric and Naloxone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Javanese Turmeric and Naloxone have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Javanese Turmeric and Naloxone combination checked?
Interactions in our licensed database are recorded against drug classes. Naloxone is filed under 1 classification, and Javanese Turmeric has documented interactions with 1 drug class — none of Naloxone's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Javanese Turmeric interact with any other medications?
Yes. Javanese Turmeric has 2 documented drug interactions in our database — Naloxone is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Naloxone interact with any supplements?
Yes. Naloxone has documented interactions with 3 supplements in our database — Javanese Turmeric is not one of them. The Naloxone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Naloxone and Javanese Turmeric?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.