Drug & supplement interaction

Krebiozen + Trametinib

Trametinib brand name: Mekinist.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 27, 2026
The bottom line No known interaction

We found no known interaction between Krebiozen and Trametinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Trametinib states a food rule worth keeping to.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Krebiozen and Trametinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Trametinib and Krebiozen in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Krebiozen at all — not against Trametinib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Krebiozen safety at a glance

Krebiozen overall Avoid Krebiozen was discredited as an ineffective and potentially fraudulent product and is not legally available.
Pregnancy Avoid Avoid entirely; it has no proven safety or benefit for anyone, including during pregnancy.
Breastfeeding Avoid Avoid entirely; it has no proven safety or benefit while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Trametinib and Krebiozen? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Trametinib’s Own FDA Label Lists

This is not an interaction — none of it involves Krebiozen. These are the most notable effects listed in the ADVERSE REACTIONS section of Trametinib’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • A stroke or mini-stroke Worth acting on
  • Severe muscle breakdown Worth acting on
  • Dehydration Worth acting on
  • Bleeding in the gut Worth acting on
  • Low sodium Worth acting on
  • Low potassium Worth acting on
  • A slow heartbeat Worth acting on
  • Heart failure Worth acting on
  • High blood sugar Worth acting on
  • Fainting Worth acting on

Showing the 10 most notable of 58 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Trametinib. Read the label on DailyMed › Where a percentage is shown, it is the share of 23,697 voluntary FDA FAERS reports for Trametinib that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Krebiozen’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Krebiozen side to compare — that is a limit of the record, not a statement that Krebiozen has no side effects.

How to take them

Some Trametinib Products Have a Food Rule — Krebiozen Should Not Break It

At least one FDA label for a product containing Trametinib says to take it on an empty stomach. Most supplements — Krebiozen included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Trametinib on its own and move Krebiozen to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Trametinib products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

MEKINIST Tablets Take MEKINIST tablets on an empty stomach (at least 1 hour before or 2 hours after a meal) [see Clinical Pharmacology (12.3)] .

From the Dosage and Administration section of the FDA label we read for Trametinib — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Trametinib

This page covers Krebiozen only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Trametinib page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

Open the Trametinib interaction page

How much people look this up

Where Krebiozen and Trametinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Krebiozen
Steady interest

#1,341 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Trametinib
Steady interest

#1,427 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources.
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Krebiozen and Trametinib records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Krebiozen

What is Krebiozen?

  • Promoted as a cancer treatment (unproven)

Krebiozen was a so-called "cancer cure" promoted in the 1950s and 1960s that was never proven to work and was discredited by U.S. government investigations. It is not a dietary supplement or herb, it is not available legally, and you should not seek it out as a treatment for any condition.

Originally claimed to be derived from horse blood serum (not a plant) · Historically sold as an injectable liquid

An interaction check asks whether these two react with each other — it does not ask whether Krebiozen is a good idea for someone in your situation. Here is what our Krebiozen record says about it on its own.

Krebiozen: dosing

There is no legitimate, established dose for Krebiozen because it is not an approved or recommended treatment. It is not a product you should obtain or use.If you come across something being sold today under the name Krebiozen or marketed as a similar "secret" cancer cure, do not use it.

From our Krebiozen monograph — the full record covers uses, side effects and every documented interaction.

Read the full Krebiozen monograph & all interactions
Medication

About Trametinib

What Is Trametinib Used For?

Brand name: Mekinist

Mekinist is used to treat cancers that have a BRAF V600E or V600K mutation — a specific genetic change that tells cancer cells to grow out of control. It can be used alone or, more often, paired with another targeted medicine called dabrafenib.

On its own, Mekinist treats certain patients with unresectable (cannot be surgically removed) or metastatic (spread to other parts of the body) melanoma who have not previously received a BRAF inhibitor. In combination with dabrafenib, Mekinist is used for metastatic or surgically treated melanoma, metastatic non-small cell lung cancer (NSCLC), locally advanced or metastatic anaplastic thyroid cancer (ATC), certain other BRAF V600E-positive solid tumors in adults and children 1 year and older, and low-grade glioma (a type of brain tumor) in children 1 year and older. A BRAF mutation must be confirmed by an FDA-approved test before starting treatment.

Most-Reported Side Effects for Trametinib

From FAERS, the FDA’s public side-effect reporting system (24,023 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fever 4,068 reports
Malignant neoplasm progression 2,040 reports
Rash 1,736 reports
Fatigue 1,516 reports
Nausea 1,496 reports
See full Trametinib drug information
Keep checking

Other Drugs & Krebiozen

Browse every other medication we’ve checked against Krebiozen — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Krebiozen against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Krebiozen list.

See the full Krebiozen interactions page
See every supplement checked against Trametinib, ranked by severity
Sources

Sources & How We Checked

We checked Krebiozen against Trametinib in the Natural Medicines interaction database and found no documented interaction on file. The medication overview comes from MedlinePlus, and supplement label details from the NIH Dietary Supplement Label Database.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Krebiozen monograph › Uses, safety, and every drug interaction in one place Trametinib supplement interactions › Every supplement checked against Trametinib, ranked by severity Trametinib drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Krebiozen and Trametinib Together: Common Questions

Is it safe to take Krebiozen with Trametinib?
We do not list a known interaction between Krebiozen and Trametinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Krebiozen and Trametinib at the same time of day?
At least one FDA label for a product containing Trametinib says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Trametinib on its own and move Krebiozen to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
Does Trametinib interact with any supplements?
Yes. Trametinib has documented interactions with 17 supplements in our database — Krebiozen is not one of them. The Trametinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Trametinib and Krebiozen?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.