Drug & supplement interaction

Lady's Bedstraw + Febuxostat

Febuxostat brand name: Uloric.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Lady's Bedstraw and Febuxostat in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Lady's Bedstraw and Febuxostat

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Febuxostat and Lady's Bedstraw in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Lady's Bedstraw at all — not against Febuxostat, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Lady's Bedstraw safety at a glance

Lady's Bedstraw overall Use caution Generally considered mild in food-like amounts, but human safety data are very limited.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Febuxostat and Lady's Bedstraw? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Febuxostat’s Own FDA Label Lists

This is not an interaction — none of it involves Lady's Bedstraw. These are the most notable effects listed in the ADVERSE REACTIONS section of Febuxostat’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Kidney stones Worth acting on
  • Hearing loss Worth acting on
  • A stroke or mini-stroke Worth acting on
  • Severe muscle breakdown Worth acting on
  • Dehydration Worth acting on
  • Bleeding in the gut Worth acting on
  • Unsteadiness Worth acting on
  • Low potassium Worth acting on
  • A slow heartbeat Worth acting on
  • Pancreatitis Worth acting on

Showing the 10 most notable of 72 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Febuxostat. Read the label on DailyMed › Where a percentage is shown, it is the share of 16,669 voluntary FDA FAERS reports for Febuxostat that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Lady's Bedstraw’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Lady's Bedstraw side to compare — that is a limit of the record, not a statement that Lady's Bedstraw has no side effects.

Everything else you take

See Every Supplement That Interacts With Febuxostat

This page covers Lady's Bedstraw only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Febuxostat page lists 56 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Siberian Cocklebur (major), Wine (major) and Ashwagandha (moderate).

By severity: 4 major · 43 moderate · 9 minor.

From our pharmacist’s overview on the Febuxostat page

“Febuxostat (Uloric) lowers uric acid to prevent gout attacks, and because the drug itself can stress the liver, its list of 56 interacting supplements deserves real vigilance rather than a quick skim. Thirty-eight of those entries have their own record of liver harm, stacking pressure on the same organ, and two of the four major-rated…”

Reviewed by 2 · Jul 18, 2026

Open the Febuxostat interaction page

How much people look this up

Where Lady's Bedstraw and Febuxostat Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lady's Bedstraw
Steady interest

#1,396 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Febuxostat
Top half

#770 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Lady's Bedstraw is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Lady's Bedstraw reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Lady's Bedstraw and Febuxostat records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Lady's Bedstraw

What is Lady's Bedstraw?

Lady's Bedstraw
  • Urinary and mild diuretic support
  • Skin complaints (topical)
  • Mild calming/sleep support
  • Digestive upset
  • Wound and inflammation soothing

Lady's bedstraw is a traditional European herb taken mostly as a tea for urinary, skin, and mild calming purposes. High-quality human research is lacking, so its benefits are not well proven, and you should talk with a pharmacist or doctor before using it—especially during pregnancy or breastfeeding.

Galium verum · Rubiaceae · Aerial parts (flowering tops, leaves, and stems) · Tea, infusion, tincture, dried herb, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Lady's Bedstraw is a good idea for someone in your situation. Here is what our Lady's Bedstraw record says about it on its own.

Lady's Bedstraw: dosing

There is no established or standardized dose for lady's bedstraw. Traditional use involves a tea made from the dried aerial parts, but exact safe and effective amounts have not been determined by research.If you choose to use a commercial product, follow the directions on the label and do not exceed them.

From our Lady's Bedstraw monograph — the full record covers uses, side effects and every documented interaction.

Read the full Lady's Bedstraw monograph & all interactions
Medication

About Febuxostat

What Is Febuxostat Used For?

Brand name: Uloric

Febuxostat (available as tablets and a dissolving oral film) is used to chronically manage hyperuricemia — high uric acid levels in the blood — in adults with gout. It is specifically for people who have not responded adequately to the highest tolerated dose of allopurinol, who cannot tolerate allopurinol, or for whom allopurinol is not appropriate.

Important limitation: febuxostat is not recommended for people who have high uric acid but no gout symptoms (asymptomatic hyperuricemia). It is also not recommended for patients whose high uric acid is caused by other conditions such as cancer treatment or Lesch-Nyhan syndrome.

Most-Reported Side Effects for Febuxostat

From FAERS, the FDA’s public side-effect reporting system (16,669 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Diarrhea 881 reports
Acute kidney injury 857 reports
Nausea 857 reports
Rash 800 reports
Gout 699 reports
See full Febuxostat drug information
Keep checking

Other Drugs & Lady's Bedstraw

Browse every other medication we’ve checked against Lady's Bedstraw — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Lady's Bedstraw References

The 2 sources that drive our Lady's Bedstraw monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Lady's Bedstraw is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH National Center for Complementary and Integrative Health (NCCIH) Source
  2. Herbs and Supplements — MedlinePlus (U.S. National Library of Medicine) Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Lady's Bedstraw and Febuxostat Together: Common Questions

Is it safe to take Lady's Bedstraw with Febuxostat?
We do not list a known interaction between Lady's Bedstraw and Febuxostat. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Febuxostat interact with any supplements?
Yes. Febuxostat has documented interactions with 56 supplements in our database — Lady's Bedstraw is not one of them. The Febuxostat interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Febuxostat and Lady's Bedstraw?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.