Drug & supplement interaction

Lungwort + Nirmatrelvir, Ritonavir

Nirmatrelvir, Ritonavir brand name: Paxlovid.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Lungwort and Nirmatrelvir, Ritonavir in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Lungwort and Nirmatrelvir, Ritonavir

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Nirmatrelvir, Ritonavir and Lungwort in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Lungwort at all — not against Nirmatrelvir, Ritonavir, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Lungwort safety at a glance

Lungwort overall Use caution Generally used in small amounts in tea, but it has not been well studied for safety in modern research.
Pregnancy Avoid Not enough safety data; best avoided during pregnancy.
Breastfeeding Avoid Not enough safety data; best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Nirmatrelvir, Ritonavir and Lungwort? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Nirmatrelvir, Ritonavir’s Own FDA Label Lists

This is not an interaction — none of it involves Lungwort. These are the most notable effects listed in the ADVERSE REACTIONS section of Nirmatrelvir, Ritonavir’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 2 of them are worth acting on rather than waiting out — marked below.

  • A higher chance of infection Worth acting on
  • An allergic reaction Worth acting on
  • A change in taste
  • Diarrhea

From the ADVERSE REACTIONS section of the FDA label for Nirmatrelvir, Ritonavir. Read the label on DailyMed › Lungwort’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Lungwort side to compare — that is a limit of the record, not a statement that Lungwort has no side effects.

Everything else you take

See Every Supplement That Interacts With Nirmatrelvir, Ritonavir

This page covers Lungwort only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Nirmatrelvir, Ritonavir page lists 176 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).

By severity: 6 major · 134 moderate · 36 minor.

From our pharmacist’s overview on the Nirmatrelvir, Ritonavir page

“Paxlovid (nirmatrelvir and ritonavir) deserves genuine care around supplements, mostly because its ritonavir component strongly blocks the liver enzyme CYP3A4. The bulk of this list is made up of ingredients that enzyme normally clears, so their levels can climb unpredictably during the five-day course.”

Reviewed by 2 · Jul 18, 2026

Open the Nirmatrelvir, Ritonavir interaction page

One more smart check

Taking Lungwort as Part of a Dietary Supplement Product? Check It for Interactions

We hold 29 real supplement products containing Lungwort, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Lungwort. Even though Lungwort itself has no known interaction with Nirmatrelvir, Ritonavir, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Lungwort and Nirmatrelvir, Ritonavir Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lungwort
Top half

#645 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Nirmatrelvir, Ritonavir
Top half

#897 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Lungwort is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Lungwort reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Lungwort and Nirmatrelvir, Ritonavir records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Lungwort

What is Lungwort?

  • Coughs and chest congestion
  • Sore throat and hoarseness
  • Bronchitis and respiratory complaints
  • Mild diarrhea
  • Wound and skin care (topical, traditional)

Lungwort (Pulmonaria officinalis) is a traditional European herb long used as a tea for coughs and minor breathing complaints, named for its lung-shaped, spotted leaves. There is very little modern human research to confirm it works, so its use rests mainly on folk tradition. Talk to a pharmacist or doctor before using it, especially during pregnancy or breastfeeding.

Pulmonaria officinalis · Boraginaceae · Leaves and flowering aerial parts (above-ground parts) · Tea (dried herb), tincture, capsules, liquid extract

An interaction check asks whether these two react with each other — it does not ask whether Lungwort is a good idea for someone in your situation. Here is what our Lungwort record says about it on its own.

Lungwort: dosing

There is no standardized, well-established dose for lungwort. Traditional use involves brewing the dried herb as a tea, but the strength of products varies widely.If you choose to use it, follow the directions on the product label and do not exceed them. Avoid long-term daily use.

From our Lungwort monograph — the full record covers uses, side effects and every documented interaction.

Read the full Lungwort monograph & all interactions
Medication

About Nirmatrelvir and Ritonavir

What Is Nirmatrelvir and Ritonavir Used For?

Brand name: Paxlovid

Paxlovid is approved to treat mild-to-moderate COVID-19 in adults who are at high risk of progressing to severe disease — meaning hospitalization or death. It is intended for people who already have symptoms and a confirmed COVID-19 diagnosis.

Paxlovid is not approved to prevent COVID-19 before or after exposure. It is a treatment, not a preventive medication.

See full Nirmatrelvir and Ritonavir drug information
Keep checking

Other Drugs & Lungwort

Browse every other medication we’ve checked against Lungwort — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Lungwort against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Lungwort list.

See the full Lungwort interactions page
See every supplement checked against Nirmatrelvir, Ritonavir, ranked by severity
Evidence & sources

Lungwort References

The 1 sources that drive our Lungwort monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Lungwort is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Pyrrolizidine Alkaloids — NIH LiverTox Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Lungwort and Nirmatrelvir, Ritonavir Together: Common Questions

Is it safe to take Lungwort with Nirmatrelvir, Ritonavir?
We do not list a known interaction between Lungwort and Nirmatrelvir, Ritonavir. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Nirmatrelvir, Ritonavir interact with any supplements?
Yes. Nirmatrelvir, Ritonavir has documented interactions with 176 supplements in our database — Lungwort is not one of them. The Nirmatrelvir, Ritonavir interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Lungwort monograph Uses, safety profile, and every drug interaction in one place Nirmatrelvir and Ritonavir drug information The full plain-English guide to this medication Nirmatrelvir, Ritonavir supplement interactions Every supplement checked against Nirmatrelvir, Ritonavir, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Nirmatrelvir, Ritonavir and Lungwort?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.