Drug & supplement interaction

Mindfulness + Metoclopramide Hydrochloride

Metoclopramide Hydrochloride brand name: Gimoti.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Mindfulness and Metoclopramide Hydrochloride in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Mindfulness and Metoclopramide Hydrochloride

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Metoclopramide Hydrochloride and Mindfulness in our sources. This does not guarantee that the combination is completely free of risk — research on Mindfulness alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Mindfulness at all — not against Metoclopramide Hydrochloride, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Mindfulness is a practice rather than something you take. Ask your care team whether the type and intensity you plan to practice are appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Mindfulness safety at a glance

Mindfulness overall Generally safe Mindfulness is generally very safe for most people and has no swallowed dose or chemical risk.
Pregnancy Generally safe Mindfulness practices are generally considered safe during pregnancy and may help with stress.
Breastfeeding Generally safe There is no known risk to breastfeeding from practicing mindfulness.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Metoclopramide Hydrochloride and Mindfulness? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Mindfulness and Metoclopramide Hydrochloride May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so practicing Mindfulness while taking the medicine can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Thoughts of self-harm Worth acting on Additional detail

    Mindfulness

    “Some studies report rare cases of anger, worsening anxiety, and thoughts of self-harm in patients, but these effects could have been caused by the underlying ailment rather than practicing mindfulness.”

    Mindfulness · Natural Medicines adverse-effect record, reported in anxiety.

    3 sources cited
    1. 100273. Hilton L, Hempel S, Ewing BA, et al. Mindfulness Meditation for Chronic Pain: Systematic Review and Meta-analysis. Ann Behav Med. 2017;51(2):199-213. PubMed
    2. 105414. Zgierska AE, Burzinski CA, Mundt MP, et al. Mindfulness-based relapse prevention for alcohol dependence: Findings from a randomized controlled trial. J Subst Abuse Treat. 2019 May;100:8-17. PubMed
    3. 109368. Hoge EA, Bui E, Mete M, Dutton MA, Baker AW, Simon NM. Mindfulness-based stress reduction vs escitalopram for the treatment of adults with anxiety disorders: A randomized clinical trial. JAMA Psychiatry. 2022:e223679. PubMed

    Metoclopramide Hydrochloride

    Listed in the ADVERSE REACTIONS section of the FDA label for Metoclopramide Hydrochloride. Read the label on DailyMed ›

  • Anxiety or restlessness Additional detail

    Mindfulness

    Recorded for Mindfulness in the same Natural Medicines adverse-effect record shown under Thoughts of self-harm above.

    Metoclopramide Hydrochloride

    Listed in the ADVERSE REACTIONS section of the FDA label for Metoclopramide Hydrochloride. Read the label on DailyMed ›

Effects for Metoclopramide Hydrochloride come from the ADVERSE REACTIONS section of its FDA label; effects for Mindfulness come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 76,710 voluntary FDA FAERS reports for Metoclopramide Hydrochloride that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Everything else you take

See Every Supplement That Interacts With Metoclopramide Hydrochloride

This page covers Mindfulness only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Metoclopramide Hydrochloride page lists 135 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major), Kava (major) and L-tryptophan (major).

By severity: 7 major · 114 moderate · 14 minor.

From our pharmacist’s overview on the Metoclopramide Hydrochloride page

“Metoclopramide (Gimoti, also sold as Reglan) calms nausea and speeds a slow stomach by acting on the brain, and that is exactly where most of these 135 supplements and herbs collide with it. This is a list to treat with genuine care.”

Reviewed by 2 · Jul 18, 2026

Open the Metoclopramide Hydrochloride interaction page

How much people look this up

Where Mindfulness and Metoclopramide Hydrochloride Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Mindfulness
Top 25%

#354 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Metoclopramide Hydrochloride
Top half

#784 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Mindfulness reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Mindfulness and Metoclopramide Hydrochloride records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Mind-body practice

About Mindfulness

What is Mindfulness?

  • Stress reduction
  • Anxiety and depression
  • Chronic pain
  • Sleep problems
  • Improving focus and emotional well-being

Mindfulness is a mind-body practice—not a pill or herb—that involves paying attention to the present moment without judgment. Research suggests it can modestly help with stress, anxiety, depression, and chronic pain for many people, and it is generally very safe. It is best used alongside, not in place of, care from your doctor or pharmacist.

Not applicable (mind-body practice) · Guided meditation, breathing exercises, body scans, mindfulness-based stress reduction (MBSR) and mindfulness-based cognitive therapy (MBCT) programs, apps, classes

An interaction check asks whether these two react with each other — it does not ask whether Mindfulness is a good idea for someone in your situation. Here is what our Mindfulness record says about it on its own.

Mindfulness: dosing

There is no standardized "dose" for mindfulness. Many structured programs, such as MBSR, run for about eight weeks with daily home practice, but you do not need a formal program to benefit.A common starting point is a few minutes of practice per day, gradually building up as it feels comfortable. Even short, regular sessions can help.

From our Mindfulness monograph — the full record covers uses, side effects and every documented interaction.

Read the full Mindfulness monograph & all interactions
Medication

About Metoclopramide Nasal Spray

What Is Metoclopramide Nasal Spray Used For?

Brand name: Gimoti

Gimoti (metoclopramide nasal spray) is approved for adults with acute and recurrent diabetic gastroparesis — a condition where diabetes damages the nerves controlling stomach emptying, causing nausea, vomiting, and bloating. It works to relieve those symptoms by helping the stomach empty more normally.

Gimoti is not recommended for children, or for adults with moderate to severe kidney or liver disease. It is also not recommended for adults taking strong CYP2D6 inhibitor medications (certain antidepressants and other drugs that slow how the body breaks down metoclopramide).

Most-Reported Side Effects for Metoclopramide Hydrochloride

From FAERS, the FDA’s public side-effect reporting system (76,710 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Tardive dyskinesia 16,218 reports
Extrapyramidal disorder 12,921 reports
Nervous system disorder 7,526 reports
Dystonia 7,115 reports
Nausea 6,495 reports
See full Metoclopramide Nasal Spray drug information
Keep checking

Other Drugs & Mindfulness

Browse every other medication we’ve checked against Mindfulness — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Mindfulness against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Mindfulness list.

See the full Mindfulness interactions page
See every supplement checked against Metoclopramide Hydrochloride, ranked by severity
Evidence & sources

Mindfulness References

The 3 references that drive our Mindfulness monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Hilton L, Hempel S, Ewing BA, et al. Mindfulness Meditation for Chronic Pain: Systematic Review and Meta-analysis. Ann Behav Med. 2017;51(2):199-213. PubMed
  2. Zgierska AE, Burzinski CA, Mundt MP, et al. Mindfulness-based relapse prevention for alcohol dependence: Findings from a randomized controlled trial. J Subst Abuse Treat. 2019 May;100:8-17. PubMed
  3. Hoge EA, Bui E, Mete M, Dutton MA, Baker AW, Simon NM. Mindfulness-based stress reduction vs escitalopram for the treatment of adults with anxiety disorders: A randomized clinical trial. JAMA Psychiatry. 2022:e223679. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Practicing Mindfulness While Taking Metoclopramide Hydrochloride: Common Questions

Is it safe to practice Mindfulness while taking Metoclopramide Hydrochloride?
We do not list a known interaction between Mindfulness and Metoclopramide Hydrochloride. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Mindfulness and Metoclopramide Hydrochloride have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Metoclopramide Hydrochloride interact with any supplements?
Yes. Metoclopramide Hydrochloride has documented interactions with 135 supplements in our database — Mindfulness is not one of them. The Metoclopramide Hydrochloride interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Mindfulness monograph Uses, safety profile, and every drug interaction in one place Metoclopramide Nasal Spray drug information The full plain-English guide to this medication Metoclopramide Hydrochloride supplement interactions Every supplement checked against Metoclopramide Hydrochloride, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Metoclopramide Hydrochloride and Mindfulness?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.