Drug & supplement interaction

Myrcia + Ingenol Mebutate

Ingenol Mebutate brand name: Picato.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Myrcia and Ingenol Mebutate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Myrcia and Ingenol Mebutate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ingenol Mebutate and Myrcia in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Myrcia safety at a glance

Myrcia overall Not established Human safety data are very limited, so caution is advised.
Pregnancy Avoid There is not enough safety information, so avoid use during pregnancy.
Breastfeeding Avoid Safety while breastfeeding is unknown, so it is best avoided.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ingenol Mebutate and Myrcia? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Ingenol Mebutate

Interactions in our licensed database are recorded against drug classes, not just single drug names. Ingenol Mebutate is filed under a single classification — topical drugs. Myrcia has documented interactions with 1 drug class — the most serious being levothyroxine (synthroid, others) (moderate) — and none of Ingenol Mebutate’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Myrcia Does Interact With Other Medications

Myrcia has 3 moderate known drug interactions in our database — Ingenol Mebutate isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Myrcia

Covers the 2,830 medications we’ve checked against Myrcia. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Ingenol Mebutate

This page covers Myrcia only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ingenol Mebutate page lists 3 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).

By severity: 2 moderate · 1 minor.

From our pharmacist’s overview on the Ingenol Mebutate page

“Ingenol mebutate (Picato) is a gel applied to the skin for actinic keratosis, the rough precancerous patches caused by sun damage, and it is deliberately harsh, producing redness, flaking, and stinging as part of how it works. The few supplement interactions on record are all skin-level ones.”

Reviewed by 2 · Jul 18, 2026

Open the Ingenol Mebutate interaction page

How much people look this up

Where Myrcia and Ingenol Mebutate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Myrcia
Steady interest

#1,376 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ingenol Mebutate
Steady interest

#2,280 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Myrcia reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Myrcia and Ingenol Mebutate records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Myrcia

What is Myrcia?

  • Blood sugar support
  • Digestive upset and diarrhea
  • Mild urinary complaints
  • Astringent for the gut
  • Traditional 'pedra-hume-caa' folk remedy

Myrcia is a group of tropical shrubs and trees in the myrtle family, used in South American folk medicine—often as a tea—mainly for blood sugar and digestive complaints. Human evidence is very limited, so it should not replace proven treatments. Talk with your pharmacist or doctor before using it, especially if you have diabetes or take other medicines.

Myrtaceae · Leaves (and sometimes bark) · Tea, dried leaf, capsules, liquid extracts

An interaction check asks whether these two react with each other — it does not ask whether Myrcia is a good idea for someone in your situation. Here is what our Myrcia record says about it on its own.

Myrcia: dosing

There is no established standardized dose for Myrcia. Traditional use is usually as a tea made from the dried leaves, but amounts vary widely and are not backed by clinical research.If you choose to try a commercial product, follow the directions on the label and do not exceed them.

From our Myrcia monograph — the full record covers uses, side effects and every documented interaction.

Read the full Myrcia monograph & all interactions
Medication

About Ingenol Mebutate Topical

What Is Ingenol Mebutate Topical Used For?

Brand name: Picato

  • Ingenol mebutate gel is used to treat actinic keratosis (flat, scaly growths on the skin caused by too much sun exposure). Ingenol mebutate is in a class of medications called cytotoxic agents. It works by killing fast-growing cells such as the abnormal cells associated with actinic keratoses.

See full Ingenol Mebutate Topical drug information
Keep checking

Other Drugs & Myrcia

Browse every other medication we’ve checked against Myrcia — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
3Moderate
0Minor
2,826No known interaction
Moderate

3 interactions

No interaction 2,826 drugs checked — show the list
Evidence & sources

Myrcia References

The 2 references that drive our Myrcia monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Russo EM, Reichelt AA, De Sa JR, et al. Clinical trial of Myrcia uniflora and Bauhinia forficata leaf extracts in normal and diabetic patients. Braz J Med Biol Res 1990;23(1):11-20.
  2. Ferreira AC, Neto JC, da Silva AC, et al. Inhibition of thyroid peroxidase by Myrcia uniflora flavonoids. Chem Res Toxicol 2006;19(3):351-55.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Myrcia and Ingenol Mebutate Together: Common Questions

Is it safe to take Myrcia with Ingenol Mebutate?
We do not list a known interaction between Myrcia and Ingenol Mebutate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Myrcia and Ingenol Mebutate combination checked?
Interactions in our licensed database are recorded against drug classes. Ingenol Mebutate is filed under 1 classification, and Myrcia has documented interactions with 1 drug class — none of Ingenol Mebutate's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Myrcia interact with any other medications?
Yes. Myrcia has 3 documented drug interactions in our database — Ingenol Mebutate is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Ingenol Mebutate interact with any supplements?
Yes. Ingenol Mebutate has documented interactions with 3 supplements in our database — Myrcia is not one of them. The Ingenol Mebutate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Ingenol Mebutate and Myrcia?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.